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Your search keyword '"Hoffman, Peter D."' showing total 1 results
Start Over Author "Hoffman, Peter D." Publisher cold spring harbor laboratory press
1 results on '"Hoffman, Peter D."'

1. Rapid accumulation of mutations during seed-to-seed propagation of mismatch-repair-defective Arabidopsis

Author

Hoffman, Peter D., Leonard, Jeffrey M., Lindberg, Gerrick E., Bollmann, Stephanie R., and Hays, John B.

Subjects
Gene mutations -- Research, Phenotype -- Research, Arabidopsis thaliana -- Genetic aspects, Genetic research, Biological sciences
Abstract

The effects of sustained mutational loading during multigenerational propagations, appearance of apparent single- and perhaps multiple-locus phenotypes and an overall trend toward decreased fitness are demonstrated. Analyses of insertion /deletion mutation at six repeat-sequence loci showed each Atmsh2-1 line to have evolved its own fingerprint the results of as many as 10 microsatellite mutations in a single line.

Published
2004

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