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Your search keyword '"Unal, Elcin"' showing total 4 results
Start Over Author "Unal, Elcin" Publisher cold spring harbor laboratory
4 results on '"Unal, Elcin"'

2. Meiotic Nuclear Pore Complex Remodeling Provides Key Insights into Nuclear Basket Organization

Author

King, Grant A, primary, Wettstein, Rahel, additional, Varberg, Joseph M, additional, Chetlapalli, Keerthana, additional, Walsh, Madison E, additional, Gillet, Ludovic, additional, Hernandez-Armenta, Claudia, additional, Beltrao, Pedro, additional, Aebersold, Ruedi, additional, Jaspersen, Sue L, additional, Matos, Joao, additional, and Unal, Elcin, additional

Published
2022
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3. Gamete Formation Resets the Aging Clock in Yeast

Author

Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT, Unal, Elcin, Amon, Angelika B, Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT, Unal, Elcin, and Amon, Angelika B

Abstract

Gametogenesis is a process whereby a germ cell differentiates into haploid gametes. We found that, in budding yeast, replicatively aged cells remove age-induced cellular damage during gametogenesis. Importantly, gametes of aged cells have the same replicative potential as those derived from young cells, indicating that life span resets during gametogenesis. Here, we explore the potential mechanisms responsible for gametogenesis-induced rejuvenation and discuss putative analogous mechanisms in higher eukaryotes., National Institutes of Health (U.S.) (grant GM62207)

Published
2018

4. Gamete Formation Resets the Aging Clock in Yeast

Author

Elçin Ünal, Angelika Amon, Massachusetts Institute of Technology. Department of Biology, Koch Institute for Integrative Cancer Research at MIT, Unal, Elcin, and Amon, Angelika B

Subjects
Genetics, Time Factors, Life span, Biological clock, Saccharomyces cerevisiae, Biology, biology.organism_classification, Biochemistry, Budding yeast, Yeast, Article, medicine.anatomical_structure, Germ Cells, Biological Clocks, medicine, Ploidy, Molecular Biology, Germ cell, Gametogenesis
Abstract

Gametogenesis is a process whereby a germ cell differentiates into haploid gametes. We found that, in budding yeast, replicatively aged cells remove age-induced cellular damage during gametogenesis. Importantly, gametes of aged cells have the same replicative potential as those derived from young cells, indicating that life span resets during gametogenesis. Here, we explore the potential mechanisms responsible for gametogenesis-induced rejuvenation and discuss putative analogous mechanisms in higher eukaryotes., National Institutes of Health (U.S.) (grant GM62207)

Published
2011

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