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An 82-year-old man presented with a two-week history of increasing shortness of breath and exercise intolerance. His medical history included chronic obstructive pulmonary disease, hypertension and chronic kidney disease. He had undergone left nephrectomy and splenectomy for abdominal trauma and had

A 53-year-old man with a history of alcohol abuse was brought in by ambulance. He had been found on a park bench, after lying there for about eight hours. The temperature outside was 15°C. Initial assessment showed that the patient had an irregular heart rate of 30 beats/min, respiration rate of 14

We commend Fralick and colleagues for their article on drug interactions with rivaroxaban.[1][1] All novel oral anticoagulants (NOACs) were introduced as at least noninferior (in some cases superior) to warfarin. In addition to high efficacy, NOACs were reported to have a better safety profile with

I would like to commend Kelsall’s[1][1] initiative to disseminate knowledge on rare diseases. The initiative will certainly help identify, stimulate, coordinate and support research, which could benefit patients who have any one of the nearly 6800 known rare diseases. I would like to draw

A 74-year-old man, a current smoker, presented with shortness of breath and a dry cough. He had a history of ventricular tachyarrhythmia treated with amiodarone (200 mg/d for 6 years), a previous myocardial infarction and coronary artery bypass surgery. On examination, bilateral crackles could be

Brook’s idea for creating an acronym[1][1] for Bosner and colleagues’ prediction rule[2][2] is commendable. It would certainly facilitate the use of the score in daily clinical practice. But perhaps the acronym would be easier to remember if it was associated with the cardiovascular system —