1. Characterization of 3 Megabase-Sized Circular Replicons fromVibrio cholerae
- Author
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Siriporn Chantaroj, Mathukorn Na-Ubol, Warawan Wongboot, Amonrattana Roobthaisong, Shigeyuki Hamada, Kazuhisa Okada, Fumito Maruyama, Ichiro Nakagawa, and Wirongrong Natakuathung
- Subjects
Microbiology (medical) ,Characterization of 3 Megabase-Sized Circular Replicons from Vibrio cholerae ,Letter ,Epidemiology ,lcsh:Medicine ,cholera ,Virulence ,medicine.disease_cause ,lcsh:Infectious and parasitic diseases ,Microbiology ,medicine ,lcsh:RC109-216 ,Replicon ,Letters to the Editor ,bacteria ,Vibrio cholerae ,replicons ,Gene ,Genetics ,Base Composition ,biology ,Circular bacterial chromosome ,lcsh:R ,Chromosome ,Molecular Sequence Annotation ,Sequence Analysis, DNA ,Thailand ,biology.organism_classification ,Vibrio ,virulence ,Infectious Diseases ,Genes, Bacterial ,lipids (amino acids, peptides, and proteins) ,Bacteria - Abstract
To the Editor: Prokaryotes typically have a single circular chromosome. However, some bacteria have >1 chromosome. Vibrio bacteria, for example, have 2 circular chromosomes: 1 (Ch1) and 2 (Ch2) (1–3). Most recognizable genes responsible for essential cell functions and pathogenicity are located on Ch1. Ch2 is also thought to encode some genes essential for normal cell function and those associated with virulence. Both chromosomes are controlled coordinately in their replication and segregation (4). Evidence suggests that Ch2 was originally a mega-plasmid captured by an ancestral Vibrio species (2,5). We report the characterization of recent isolates of V. cholerae O1 from Thailand that carry a novel gigantic replicon (Rep.3) in addition to Ch1 and Ch2.
- Published
- 2015
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