1. SARS-CoV-2 Seroprevalence in a Rural and Urban Household Cohort during First and Second Waves of Infections, South Africa, July 2020–March 2021
- Author
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Stephen Tollman, Limakatso Lebina, Cheryl Cohen, Anne von Gottberg, Mzimasi Neti, Amelia Buys, Kathleen Kahn, Neil A. Martinson, Jinal N. Bhiman, Jocelyn Moyes, Floidy Wafawanaka, Marieke Brauer, Meredith McMorrow, Waasila Jassat, Nicole Wolter, F. Xavier Gómez-Olivé, Jackie Kleynhans, Jacques du Toit, and Stefano Tempia
- Subjects
Adult ,Rural Population ,Microbiology (medical) ,infection–fatality ratio ,2019-20 coronavirus outbreak ,Epidemiology ,coronaviruses ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Infectious and parasitic diseases ,RC109-216 ,Limited access ,respiratory infections ,South Africa ,Seroepidemiologic Studies ,Humans ,Medicine ,Seroprevalence ,viruses ,SARS-CoV-2 Seroprevalence in a Rural and Urban Household Cohort during First and Second Waves of Infections, South Africa, July 2020–March 2021 ,Child ,seroprevalence ,Rural community ,SARS-CoV-2 ,business.industry ,Research ,COVID-19 ,Middle Aged ,Urban community ,zoonoses ,Infectious Diseases ,coronavirus disease ,Cohort ,Age distribution ,infection–hospitalization ratio ,business ,infection–case ratio ,severe acute respiratory syndrome coronavirus 2 ,Demography - Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections may be underestimated because of limited access to testing. We measured SARS-CoV-2 seroprevalence in South Africa every 2 months during July 2020–March 2021 in randomly selected household cohorts in 2 communities. We compared seroprevalence to reported laboratory-confirmed infections, hospitalizations, and deaths to calculate infection–case, infection–hospitalization, and infection–fatality ratios in 2 waves of infection. Post–second wave seroprevalence ranged from 18% in the rural community children
- Published
- 2021
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