1. Maripa Virus RNA Load and Antibody Response in Hantavirus Pulmonary Syndrome, French Guiana
- Author
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Anne Lavergne, Hatem Kallel, Séverine Matheus, Claire Mayence, Dominique Rousset, Vincent Lacoste, Stéphanie Houcke, Benoit de Thoisy, Bhety Labeau, David Moua, Alexandre Roux, Damien Donato, Didier Hommel, Laetitia Bremand, Institut Pasteur de la Guyane, Réseau International des Instituts Pasteur (RIIP), Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], Laboratoire des Interactions Virus-Hôtes [Cayenne, Guyane Française], Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), This study was supported in part by the Centre National de Référence des Hantavirus Laboratoire Associé financed by the Institut Pasteur de la Guyane and Santé Publique France (Saint-Maurice, France). This study benefited from the RESERVOIRS program, which is supported by the European Regional Development Fund and Fonds Européen de Developpement Régional, and received assistance from Région Guyane and Direction Régionale pour la Recherche et la Technologie and Investissement d’Avenir grants managed by the Agence Nationale de la Recherche (CEBA ANR-10-LABEX-25-01)., We thank Sandrine Fernandes-Pellerin and Nathalie Jolly for their helpful expertise on ethics issues relevant to this study. In addition, we acknowledge Thierry Carage for his assistance., ANR-10-LABX-0025,CEBA,CEnter of the study of Biodiversity in Amazonia(2010), and ANR-10-LABX-25-01/10-LABX-0025,CEBA,CEnter of the study of Biodiversity in Amazonia(2010)
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Male ,0301 basic medicine ,Orthohantavirus ,Epidemiology ,viruses ,lcsh:Medicine ,hantavirus ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,MESH: Hantavirus Pulmonary Syndrome/mortality ,Medicine ,MESH: Hantavirus / immunology ,MESH: Aged ,[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases ,MESH: Middle Aged ,biology ,MESH: RNA, Viral/blood ,Dispatch ,MESH: Hantavirus/immunology ,MESH: Hantavirus Pulmonary Syndrome/diagnosis ,Middle Aged ,Viral Load ,MESH: Hantavirus Pulmonary Syndrome / virology ,French Guiana ,3. Good health ,[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology ,Infectious Diseases ,[SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology ,arboviruses ,[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology ,RNA, Viral ,Maripa virus ,MESH: RNA, Viral / blood ,Antibody ,MESH: Viral Load ,Viral load ,Maripa Virus RNA Load and Antibody Response in Hantavirus Pulmonary Syndrome, French Guiana ,Adult ,Microbiology (medical) ,MESH: Hantavirus Pulmonary Syndrome / diagnosis ,hantavirus pulmonary syndrome ,MESH: Hantavirus/isolation & purification ,Virus ,lcsh:Infectious and parasitic diseases ,Diagnosis, Differential ,03 medical and health sciences ,Immune system ,MESH: Diagnosis, Differential ,MESH: Hantavirus Pulmonary Syndrome / mortality ,MESH: French Guiana ,MESH: Hantavirus / isolation & purification ,Humans ,lcsh:RC109-216 ,MESH: Hantavirus Pulmonary Syndrome/virology ,Aged ,Hantavirus ,Hantavirus pulmonary syndrome ,MESH: Humans ,business.industry ,lcsh:R ,RNA ,MESH: Adult ,antibody response ,Virology ,MESH: Male ,030104 developmental biology ,Antibody response ,biology.protein ,business - Abstract
International audience; We report viral RNA loads and antibody responses in 6 severe human cases of Maripa virus infection (2 favorable outcomes) and monitored both measures during the 6-week course of disease in 1 nonfatal case. Further research is needed to determine prevalence of this virus and its effect on other hantaviruses.
- Published
- 2018
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