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1. SARS-CoV-2 Seroprevalence in a Rural and Urban Household Cohort during First and Second Waves of Infections, South Africa, July 2020–March 2021

Author

Jackie Kleynhans, Stefano Tempia, Nicole Wolter, Anne von Gottberg, Jinal N. Bhiman, Amelia Buys, Jocelyn Moyes, Meredith L. McMorrow, Kathleen Kahn, F. Xavier Gómez-Olivé, Stephen Tollman, Neil A. Martinson, Floidy Wafawanaka, Limakatso Lebina, Jacques du Toit, Waasila Jassat, Mzimasi Neti, Marieke Brauer, and Cheryl Cohen

Subjects
COVID-19, coronavirus disease, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, coronaviruses, viruses, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections may be underestimated because of limited access to testing. We measured SARS-CoV-2 seroprevalence in South Africa every 2 months during July 2020–March 2021 in randomly selected household cohorts in 2 communities. We compared seroprevalence to reported laboratory-confirmed infections, hospitalizations, and deaths to calculate infection–case, infection–hospitalization, and infection–fatality ratios in 2 waves of infection. Post–second wave seroprevalence ranged from 18% in the rural community children

Published
2021
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