1. Illness Severity in Hospitalized Influenza Patients by Virus Type and Subtype, Spain, 2010-2017.
- Author
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Delgado-Sanz, Concepción, Mazagatos-Ateca, Clara, Oliva, Jesús, Gherasim, Alin, and Larrauri, Amparo
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INFLUENZA , *INFLUENZA A virus , *HOSPITAL patients , *ADULT respiratory distress syndrome , *INTENSIVE care units , *INFLUENZA epidemiology , *AGE distribution , *RETROSPECTIVE studies , *SEVERITY of illness index , *HOSPITAL care , *INFLUENZA A virus, H1N1 subtype , *INFLUENZA A virus, H3N2 subtype , *LONGITUDINAL method ,ADMISSION & discharge - Abstract
We conducted a retrospective cohort study to assess the effect of influenza virus type and subtype on disease severity among hospitalized influenza patients in Spain. We analyzed the cases of 8,985 laboratory-confirmed case-patients hospitalized for severe influenza by using data from a national surveillance system for the period 2010-2017. Hospitalized patients with influenza A(H1N1)pdm09 virus were significantly younger, more frequently had class III obesity, and had a higher risk for pneumonia or acute respiratory distress syndrome than patients infected with influenza A(H3N2) or B (p<0.05). Hospitalized patients with influenza A(H1N1)pdm09 also had a higher risk for intensive care unit admission, death, or both than patients with influenza A(H3N2) or B, independent of other factors. Determining the patterns of influenza-associated severity and how they might differ by virus type and subtype can help guide planning and implementation of adequate control and preventive measures during influenza epidemics. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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