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San Diego's clean technology sector is flourishing: From solar power and wind technologies to clean transportation, algae-based industrial chemicals and biofuels, the region is lush with companies that are pushing [...]

Pfenex Inc., a spinoff of Dow Chemical Co., is the latest San Diego biotech to file for an initial public offering. The company is looking to raise $74.8 million as [...]

Ayub Khattak's big idea started with the swine flu. Sneezing, hacking and panicking would-be flu patients were lining up at doctors' offices and emergency departments in 2009, worried they'd caught [...]

Ligand Pharmaceuticals Inc. has forged a creative new licensing deal with a small La Jolla startup--further indication that the once-beleaguered biotech is making a marked turnaround. Ligand (Nasdaq: LGND) has [...]

Venture capital investment in San Diego's life sciences arena is on the upswing, boosted by the lingering positive effects of a bullish biotech market, according to area VCs and a [...]

Michelle Lee left medical school to pursue her passion for nursing, preferring the more intimate contact nurses tend to have with patients over the 'in-and-out' bedside manner she sees as [...]

Lumena Pharmaceuticals Inc. is being snapped up by Irish drugmaker Shire PLC for $260 million, scrapping the San Diego biotech's plan to raise $75 million in an initial public offering. [...]

Well-funded La Jolla drugmaker Ambrx Inc. plans to raise up to $86 million in an initial public offering, hoping to draw in more capital in the midst of an erratic [...]

The recent $48 million investment in Verdezyne Inc. involving a Malaysian corporation drew a couple of high-profile onlookers to the signing that closed the deal. The attendance of President Barack [...]

The wheels are in motion for the first legal marijuana dispensaries to open in San Diego, amid a recent crackdown on illegally operated dispensaries in the region. Nearly 70 applicants [...]

Enrolling the Latino population in the state-run health insurance exchange has long been viewed a linchpin in the success of Covered California--and Obamacare as a whole. Despite initial marketing and [...]

It's hair today that's gone tomorrow with Beauty By Dolly--a wildly popular San Diego salon that specializes in the ancient art of yanking out unwanted facial hairs with a simple [...]

Despite its reportedly promising treatment for liver failure, San Diego-based Vital Therapies Inc. has had a bit of a rough go as it hit the markets. The company raised more [...]

Public companies in San Diego's biotech industry have been on quite the roller coaster, a trend reflected in how that sector is represented in the San Diego Business Journal's new [...]

The Scripps Research Institute has formed a new drug discovery company called Scripps Advance to fast-track the translation of early-stage biomedical research into clinical development and, ultimately, commercialization. The project's [...]

The final surge of Covered California signups ended April 15 with more than 1.4 million enrolled, vastly exceeding initial estimates, despite some confusion in the signup process. However, the number [...]

Biofuels don't hold the same cachet or glamour they once had, but companies like San Diego's Genomatica Inc. are showing that the market opportunity is still there for biorenewable products. [...]

Lauded San Diego philanthropist Malin Burnham has teamed with Tom Gephart, an old-school venture capitalist, to launch a $200 million 'Cross-Border Innovation Fund,' aiming to finance 10 to 20 startups [...]

Sirenas Marine Discovery Inc. is in an enviable position--it's actually turning away investors as it turns to the ocean's depths as a promising source for potential new drugs. The La [...]

AnaptysBio Inc., a player in the hot field of cancer immunotherapy, has attracted $ 17 million up front in a drug development rights deal with Massachusetts-based Tesaro Inc. that could [...]

Chicago private equity firm GTCR is doling out up to $300 million to launch Maravai Life Sciences Inc. in San Diego, tapping the expertise of former Gen-Probe Inc. executives Carl [...]

Shepherding thousands of employees through a high-profile merger is highly daunting, but Mark Stevenson considers himself equal to the task. The veteran biotech executive has, after all, done it before. [...]

San Diego-based Abide Therapeutics Inc. has partnered with biotech titan Celgene Corp. to develop new drugs in inflammation and immunology, receiving $50 million upfront in the deal. Princeton, N.J.-based Celgene [...]

San Diego super scientist J. Craig Venter has launched a new company, Human Longevity Inc., with an ambitious --albeit ambiguous--pursuit: make people live longer. The materials and methods of this [...]

Adamis Pharmaceuticals Corp. stands unique among San Diego's many drugmakers: It's going generic. Headed by biotech vet Dennis Carlo, Adamis (Nasdaq: ADMP) is eschewing the San Diego life science sector's [...]

North County, home to nearly 900,000 and stretching across beach, mountain and desert, is full of contradiction. The region boasts a diverse swath of fast-growing industry clusters--but also has an [...]

San Diego-based Cadence Pharmaceuticals Inc. is being acquired by Irish specialty drug maker Mallinckrodt PLC for $1.3 billion. Mallinckrodt (NYSE: MNK) is paying $14 per share in cash for Cadence [...]

Regulators have deemed DexCom Inc's newest blood sugar monitor safe and accurate for children, opening an underserved--and lucrative--juvenile diabetes market for a company whose stock and revenue have already been [...]

More than 45,000 San Diegans signed up for health insurance via Covered California through the end of December. The vast majority of them qualified for income-based subsidies and chose plans [...]

The woman had extreme stomach pains and was on the verge of passing out. Tri-City Medical Center was a stone's throw away, but she adamantly refused to go there because [...]

What a difference time has made for Illumina Inc. Things seemed dark to some a little more than two years ago when the San Diego-based genome sequencing equipment maker's stock [...]

Accelrys Inc., a San Diego life sciences software company that's built itself on a series of mergers and acquisitions, has itself been acquired by France's Dassault Systemes SA for $750 [...]

Blood banks are bleeding: Donor rates are dropping, and hospitals don't use or need as much blood as they once did. But San Diego Blood Bank's new CEO, David Wellis, [...]

Two leaders of notable San Diego business groups recently resigned to join the private sector--David Gollaher, president and CEO of the California Health Institute, and Holly Smithson, president and chief [...]

Irish pharmaceutical giant Shire PLC is shedding the assets of its unprofitable La Jolla-based Dermagraft business, ending an initially promising but ultimately spastic tenure in the San Diego region. Shire [...]

Receptos Inc. has raked in $117.4 million in a secondary public offering--right on the heels of its initial public offering last May, in which it raised $73 million. The funds [...]

Medistem Inc., a San Diego-based stem cell company that harnesses regenerative cells found in menstrual blood, will be acquired for about $26 million by Intrexon Corp.--a high-profile synthetic biology company [...]

The Affordable Care Act will bring sweeping change to health care in 2014 in San Diego and across the country, as providers and consumers adjust to the new norm of [...]

Lynette Lampton expected health insurance premiums to rise in 2014. She didn't think they'd go up 57 percent. Lampton, the human resources manager of San Diego-based Christian Wheeler Engineering, faced [...]

Advances in medical information technology will help ease mounting health care costs in 2014--and much of the groundwork is being laid in San Diego. Area health systems are beefing up [...]

Volcano Corp. has authorized a $200 million share repurchase program--an initiative in line with advice from an activist investor who is reportedly grooming the company as an acquisition target. In [...]

Palomar Health will be the first in California to join the Mayo Clinic Care Network, a group of about two dozen hospitals that are affiliated with the prestigious Mayo Clinic [...]

2013 SPECIAL COVERAGE YEAR IN REVIEW This has been a banner year for the life sciences initial public offering. Despite a recent downtick in IPO activity, San Diego has been [...]

The city of San Diego has a plan to reduce what it spends for electricity to power its streetlights--and maybe generate revenue in the process. The city is piloting a [...]

British pharmaceutical giant GlaxoSmithKline PLC is expanding its West Coast presence with several key moves in San Diego--and its unique partnership with La Jolla-based Avalon Ventures is front and center. [...]

Irish drugmaker Shire PLC has halted construction of its more than 150,000-square-foot regenerative medicine building in Sorrento Mesa. The new building was meant to house the production of Shire's diabetic [...]

San Diego-based CareFusion Corp. will acquire the Vital Signs division of GE Healthcare for $500 million. The medical device maker plans to increase its respiratory care and anesthesiology business, scale [...]

San Diego-based Zogenix Inc. plans to use most of the proceeds from a recent $60 million public offering to triple its sales force and commercialize its newly approved narcotic painkiller, [...]

San Diego is a beacon nationally for its advances in regenerative medicine and stem cell research, but the field has faltered in its transition from the bench to the bedside. [...]

Santarus Inc., a San Diego maker of diabetes and gastrointestinal drugs, has agreed to be acquired for $2.6 billion by Salix Pharmaceuticals Ltd. Raleigh, N.C.-based Salix will acquire all of [...]