1. Natriuretic peptides and heart failure
- Author
-
Peter Mossop, Craig S. McLachlan, and Haidong Yu
- Subjects
medicine.medical_specialty ,medicine.drug_class ,Sensitivity and Specificity ,Ventricular Dysfunction, Left ,Reference Values ,Reference level ,Internal medicine ,Natriuretic Peptide, Brain ,Natriuretic peptide ,Medicine ,Humans ,Letters ,Heart Failure ,Likelihood Functions ,business.industry ,Bayes Theorem ,General Medicine ,medicine.disease ,Prognosis ,Peptide Fragments ,Dyspnea ,Treatment Outcome ,ROC Curve ,Heart failure ,Cardiology ,business ,Atrial Natriuretic Factor ,Biomarkers - Abstract
The natriuretic peptides are a family of related hormones that play a crucial role in cardiovascular homeostasis. They have recently emerged as potentially important clinical markers in heart failure. Recent data have suggested an important role for these markers in establishing the diagnosis of heart failure in patients with unexplained dyspnea in both acute care and ambulatory settings. Other clinical uses of the natriuretic peptides, such as screening for asymptomatic ventricular dysfunction, establishing prognosis or guiding titration of drug therapy, are under investigation but have not yet sufficiently been validated for widespread clinical use.
- Published
- 2007