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Pit cave 6 on Pointe Gros Rempart (Baie-Mahault, La Désirade, French West Indies) is a stratified fossil-bearing site. While the archaeological material and faunal remains from the oldest assemblage demonstrate it to have formed during the Amerindian period, the second assemblage dates to the first one-hundred years of the island's colonial period (mid-18th to mid-19th centuries). Faunal analysis revealed the presence of 4 now locally extinct or extinct species, three of which have never before been documented on La Désirade ( Ameiva sp., Leiocephalus cf. cuneus and Alsophis sp.). Changing faunal spectrums (invertebrates and vertebrates) due to environmental destabilisation combined with aspects of the island's colonial economy demonstrate habitat degradation and over-grazing to be the principal causes of extinctions and or extirpations. [ABSTRACT FROM AUTHOR]