1. No differences in muscle protein synthesis rates following ingestion of wheat protein, milk protein, and their protein blend in healthy, young males
- Author
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Tim Snijders, Lisette C. P. G. M. de Groot, Philippe J. M. Pinckaers, Janneau van Kranenburg, Lex B. Verdijk, Luc J. C. van Loon, Floris K Hendriks, Imre W. K. Kouw, Physiotherapy, Human Physiology and Anatomy, Human Physiology and Sports Physiotherapy Research Group, Humane Biologie, RS: NUTRIM - R3 - Respiratory & Age-related Health, and RS: NUTRIM - R1 - Obesity, diabetes and cardiovascular health
- Subjects
Male ,STIMULATION ,Anabolism ,protein blends ,LEUCINE ,Medicine (miscellaneous) ,Muscle Proteins ,Muscle protein synthesis ,Young healthy males ,Dairy ,Eating ,Young Adult ,Double-Blind Method ,Fractional synthesis rate ,plant based proteins ,Protein biosynthesis ,young healthy males ,Ingestion ,Humans ,Food science ,Muscle, Skeletal ,RESISTANCE EXERCISE ,Young male ,Essential amino acid ,Triticum ,IN-VIVO ,VLAG ,chemistry.chemical_classification ,OLDER ,Nutrition and Dietetics ,Milk protein ,REST ,food and beverages ,Milk Proteins ,Postprandial Period ,Nutritional Biology ,ANABOLISM ,Amino acid ,chemistry ,dairy ,BIOPSY ,fractional synthesis rate ,SKELETAL-MUSCLE ,CASEIN ,Protein blends ,Dietary Proteins ,Myofibril ,muscle protein synthesis ,Plant-based proteins - Abstract
Plant-derived proteins have been suggested to have less anabolic properties when compared with animal-derived proteins. Whether blends of plant- and animal-derived proteins can compensate for their lesser anabolic potential has not been assessed. The present study compares post-prandial muscle protein synthesis rates following the ingestion of milk protein with wheat protein or a blend of wheat plus milk protein in healthy, young males. In a randomised, double-blind, parallel-group design, 36 males (23 (sd 3) years) received a primed continuous L-[ring-13C6]-phenylalanine infusion after which they ingested 30 g milk protein (MILK), 30 g wheat protein (WHEAT) or a 30 g blend combining 15 g wheat plus 15 g milk protein (WHEAT+MILK). Blood and muscle biopsies were collected frequently for 5 h to assess post-prandial plasma amino acid profiles and subsequent myofibrillar protein synthesis rates. Ingestion of protein increased myofibrillar protein synthesis rates in all treatments (P < 0·001). Post-prandial myofibrillar protein synthesis rates did not differ between MILK v. WHEAT (0·053 (sd 0·013) v. 0·056 (sd 0·012) %·h−1, respectively; t test P = 0·56) or between MILK v. WHEAT+MILK (0·053 (sd 0·013) v. 0·059 (sd 0·025) %·h−1, respectively; t test P = 0·46). In conclusion, ingestion of 30 g milk protein, 30 g wheat protein or a blend of 15 g wheat plus 15 g milk protein increases muscle protein synthesis rates in young males. Furthermore, muscle protein synthesis rates following the ingestion of 30 g milk protein do not differ from rates observed after ingesting 30 g wheat protein or a blend with 15 g milk plus 15 g wheat protein in healthy, young males.
- Published
- 2021