Innovation is generally considered to be the antidote to economic stagnation. But while the coupling of ‘responsible' and 'innovation’ has been much discussed, that of 'responsible stagnation' has gone largely unexplored. In this book, we take this concept seriously as a means to question the political economy of science, technology and innovation, both as policy and as process, and the problems which arise from unquestioned emphasis on innovation as the means to increase GDP. The book argues that examining what 'responsible stagnation' might contribute opens new space in the growing global discussion about RI, incorporating innovation in non-market oriented processes, goods and services which have strong societal benefit but do not necessarily contribute to GDP. It examines the conundrum of diminishing productivity returns and increased environmental and social hazards associated with attempts to increase GDP, and how taking a growth-agnostic approach contributes to recalibrating innovation around responsibility as its focal point. Drawing on insights from ecological and steady state economics, Science and Technology Studies, and social innovation across the world, this interdisciplinary group of scholars questions how the growth paradigm shapes and limits the innovation space, and how decoupling innovation from growth points toward myriad possibilities for facilitating human well-being in more environmentally and socially responsible ways.