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A male metal worker, who has never smoked, contracted debilitating dyspnoea in 2003 which then deteriorated until 2007. Spirometry and chest x-rays provided no diagnosis. A 3D-image of the airways was reconstructed from a high-resolution CT (HRCT) in 2007, showing peribronchial air on the right side, mostly along the presegmental airways. After digital subtraction of the image of the peribronchial air, a hole on the cranial side of the right main bronchus was detected. The perforation could be identified at the re-examination of HRCTs in 2007 and 2009, but not in 2010 when it had possibly healed. The occupational exposure of the patient to evaporating chemicals might have contributed to the perforation and hampered its healing. A 3D HRCT reconstruction should be considered to detect bronchial anomalies, including wallperforation, when unexplained dyspnoea or other chest symptoms call for extended investigation. [ABSTRACT FROM AUTHOR]

A male metal worker, who has never smoked, contracted debilitating dyspnoea in 2003 which then deteriorated until 2007. Spirometry and chest x-rays provided no diagnosis. A 3D-image of the airways was reconstructed from a high-resolution CT (HRCT) in 2007, showing peribronchial air on the right side, mostly along the presegmental airways. After digital subtraction of the image of the peribronchial air, a hole on the cranial side of the right main bronchus was detected. The perforation could be identified at the re-examination of HRCTs in 2007 and 2009, but not in 2010 when it had possibly healed. The occupational exposure of the patient to evaporating chemicals might have contributed to the perforation and hampered its healing. A 3D HRCT reconstruction should be considered to detect bronchial anomalies, including wallperforation, when unexplained dyspnoea or other chest symptoms call for extended investigation. [ABSTRACT FROM AUTHOR]

Assesses the risk of cancer development among patients with condylomata acuminata at the Karolinska Hospital in Stockholm, Sweden. Prevalence of malignant tumor; Number of expected national incidence; Absence of significant increase in genital cancer; Occurrence of genitourinary cancers in males.

Examines the effects of imprinting as a mechanism contributing to opiate addiction in adults in Stockholm, Sweden. Rate of mortality associated with opiate addiction; Administration of opiates, barbiturates and nitrous oxide to mothers during labor; Conclusions that imprinting is a causative mechanism for drug addiction.

Investigates the risk of breast cancer after legal abortion during the first trimester in Sweden. Association of abortions to breast cancer; Statistics of women with breast cancer that had undergone abortion; Calculation of the years of women at great risk of breast cancer.

Examines the use of total serum cholesterol concentration in the prediction of mortality from injuries in Varmland, Sweden. Negative relation between cholesterol concentration and mortality from injuries in men; Excess risk in men and women caused by suicide; Relation between serum level concentration and suicide.

Examines the implication of serum sialic acid concentrations for the diagnosis of cardiovascular diseases in Sweden. Influence of smoking on sialic acid concentration; Correlation of age with increase in sialic acid; Differences in the sialic acid concentration of both gender.