355 results
Search Results
2. Interventions employed to improve intrahospital handover: a systematic review.
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Robertson, Eleanor R., Morgan, Lauren, Bird, Sarah, Catchpole, Ken, and McCulloch, Peter
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ADVERSE health care events ,CINAHL database ,DATABASE evaluation ,EXPERIMENTAL design ,HOSPITAL care ,MEDICAL information storage & retrieval systems ,MEDLINE ,QUALITY assurance ,RESEARCH funding ,TERMS & phrases ,SYSTEMATIC reviews ,EVIDENCE-based medicine ,PROFESSIONAL practice ,PREVENTION - Abstract
Background Modern medical care requires numerous patient handovers/handoffs. Handover error is recognised as a potential hazard in patient care, and the information error rate has been estimated at 13%. While accurate, reliable handover is essential to high quality care, uncertainty exists as to how intrahospital handover can be improved. This systematic review aims to evaluate the effectiveness of interventions aimed at improving the quality and/ or safety of the intrahospital handover process. Methods We searched for articles on handover improvement interventions in EMBASE, MEDLINE, HMIC and CINAHL between January 2002 and July 2012. We considered studies of: staff knowledge and skills, staff behavioural change, process change or patient outcomes. Results 631 potentially relevant papers were identified from which 29 papers were selected for inclusion (two randomised controlled trials and 27 uncontrolled studies). Most studies addressed shift-change handover and used a median of three outcome measures, but there was no outcome measure common to all. Poor study design and inconsistent reporting methods made it difficult to reach definite conclusions. Information transfer was improved in most relevant studies, while clinical outcome improvement was reported in only two of 10 studies. No difference was noted in the likelihood of success across four types of intervention. Conclusions The current literature does not confirm that any methodology reliably improves the outcomes of clinical handover, although information transfer may be increased. Better study designs and consistency of the terminology used to describe handover and its improvement are urgently required. [ABSTRACT FROM AUTHOR]
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- 2014
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3. Impact of elevated fine particulate matter (PM2.5) during landscape fire events on cardiorespiratory hospital admissions in Perth, Western Australia.
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Shirangi, Adeleh, Ting Lin, Yun, Grace, Williamson, Grant J., Franklin, Peter, Le Jian, Reid, Christopher M., and Jianguo Xiao
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CARDIOVASCULAR disease prevention ,RESPIRATORY disease prevention ,POISSON distribution ,WILDFIRES ,PATIENTS ,RESEARCH funding ,HOSPITAL admission & discharge ,HOSPITAL care ,MULTIVARIATE analysis ,ENVIRONMENTAL exposure ,PARTICULATE matter ,SOCIODEMOGRAPHIC factors ,CONFIDENCE intervals - Published
- 2024
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4. Need to systematically identify and mitigate risks upon hospitalisation for patients with chronic health conditions.
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Pronovost, Peter J. and Carrington, Eboné M.
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MEDICAL screening equipment ,RISK assessment ,HOME care services ,HEALTH status indicators ,MEDICAL informatics ,PATIENT safety ,HOSPITAL care ,RISK management in business ,MEDICAL care ,OUTPATIENT medical care ,EVALUATION of medical care ,CHRONIC diseases ,PROFESSIONS ,CONCEPTUAL structures ,ELECTRONIC health records ,QUALITY assurance ,HEALTH care teams ,LEGAL compliance - Published
- 2024
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5. Implications of child poverty reduction targets for public health and health inequalities in England: a modelling study between 2024 and 2033.
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McCabe, Ronan, Pollack, Roxana, Broadbent, Philip, Thomson, Rachel M., Igelström, Erik, Pearce, Anna, Bambra, Clare, Bennett, Davara Lee, Alexandros, Alexiou, Daras, Konstantinos, Robinson, David Taylor, Barr, Benjamin, and Katikireddi, Srinivasa Vittal
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CHILDREN'S health ,ANEMIA ,RESEARCH funding ,INFANT mortality ,HOSPITAL care ,DESCRIPTIVE statistics ,HEALTH equity ,PUBLIC health ,COMPARATIVE studies ,CONFIDENCE intervals ,POVERTY - Published
- 2024
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6. Interventions for smoking cessation in hospitalised patients: a systematic review.
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Munafò, M, Rigotti, N., Lancaster, T., Stead, L., Murphy, M., and Munafò, M
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CIGARETTE smokers ,SMOKING cessation ,HOSPITAL admission & discharge ,SUBSTANCE abuse ,PERSONALITY disorders ,EMPLOYEE assistance programs ,CLINICAL trials ,THERAPEUTIC use of nicotine ,NICOTINIC agonists ,HOSPITAL care ,TREATMENT effectiveness ,ODDS ratio ,THERAPEUTICS - Abstract
Background: An admission to hospital provides an opportunity to help people stop smoking. Individuals may be more open to help at a time of perceived vulnerability, and may find it easier to quit in an environment where smoking is restricted or prohibited. Providing smoking cessation services during hospitalisation may help more people to attempt and sustain an attempt to quit. The purpose of this paper is to systematically review the effectiveness of interventions for smoking cessation in hospitalised patients.Methods: We searched the Cochrane Tobacco Addiction Group register, CINAHL, and the Smoking and Health database for studies of interventions for smoking cessation in hospitalised patients. Randomised and quasi-randomised trials of behavioural, pharmacological, or multi-component interventions to help patients stop smoking conducted with hospitalised patients who were current smokers or recent quitters were included. Studies of patients admitted for psychiatric disorders or substance abuse, those that did not report abstinence rates, and those with follow up of less than 6 months were excluded. Two of the authors extracted data independently for each paper, with assistance from others.Results: Intensive intervention (inpatient contact plus follow up for at least 1 month) was associated with a significantly higher cessation rate compared with controls (Peto odds ratio (OR) 1.82, 95% CI 1.49 to 2.22). Any contact during hospitalisation followed by minimal follow up failed to detect a statistically significant effect on cessation rate, but did not rule out a 30% increase in smoking cessation (Peto OR 1.09, 95% CI 0.91 to 1.31). There was insufficient evidence to judge the effect of interventions delivered only during the hospital stay. Although the interventions increased quit rates irrespective of whether nicotine replacement therapy (NRT) was used, the results for NRT were compatible with other data indicating that it increases quit rates. There was no strong evidence that clinical diagnosis affected the likelihood of quitting.Conclusions: High intensity behavioural interventions that include at least 1 month of follow up contact are effective in promoting smoking cessation in hospitalised patients. [ABSTRACT FROM AUTHOR]- Published
- 2001
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7. Associations between neighbourhood deprivation, ethnicity and maternal health outcomes in England: a nationwide cohort study using routinely collected healthcare data.
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Geddes-Barton, Dorothea, Ramakrishnan, Rema, Knight, Marian, and Goldacre, Raph
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DISEASE risk factors ,MORTALITY risk factors ,RISK assessment ,NATIONAL health services ,MATERNAL health services ,WOMEN ,RESEARCH funding ,SOCIAL determinants of health ,LOGISTIC regression analysis ,HOSPITAL care ,MEDICAL care ,SOCIOECONOMIC factors ,EVALUATION of medical care ,RETROSPECTIVE studies ,PREGNANT women ,DESCRIPTIVE statistics ,LONGITUDINAL method ,ODDS ratio ,HEALTH behavior ,PREGNANCY complications ,HEALTH equity ,EVIDENCE-based medicine ,COMPARATIVE studies ,CONFIDENCE intervals ,NEIGHBORHOOD characteristics ,SOCIAL isolation - Published
- 2024
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8. Examining the hospital costs of children born into relative deprivation in England.
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Dale, Veronica, Gutacker, Nils, Bradshaw, Jonathan, and Bloor, Karen
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NATIONAL health services ,COST effectiveness ,RESEARCH funding ,HOSPITAL care ,RETROSPECTIVE studies ,DESCRIPTIVE statistics ,POPULATION geography ,LONGITUDINAL method ,MEDICAL records ,ACQUISITION of data ,HEALTH equity ,SOCIAL isolation ,HOSPITAL costs ,ECONOMICS - Published
- 2024
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9. Intersectional inequalities in paediatric infectious diseases: a national cohort study in Sweden.
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Videholm, Samuel, Silfverdal, Sven Arne, and Gustafsson, Per E.
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COMMUNICABLE disease epidemiology ,RESEARCH funding ,CHILD health services ,HOSPITAL care ,LOGISTIC regression analysis ,SEX distribution ,SOCIOECONOMIC factors ,RETROSPECTIVE studies ,INFECTION ,INTERSECTIONALITY ,LONGITUDINAL method ,CONCEPTUAL structures ,HEALTH equity ,DISEASE incidence - Published
- 2024
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10. Deprescribing in older adults with polypharmacy.
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Hung, Anna, Yoon Hie Kim, and Pavon, Juliessa M.
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MEDICAL protocols ,DRUG side effects ,FRAIL elderly ,HOSPITAL care ,TEACHING aids ,POLYPHARMACY ,DEPRESCRIBING ,FUNCTIONAL status ,HOSPITAL mortality ,MEDICATION error prevention ,PATIENT care ,DECISION making ,COGNITION disorders ,MEDICAL care costs ,ACCIDENTAL falls ,OLD age - Published
- 2024
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11. New Zealand's Prospective Outcomes of Injury Study-10 years on (POIS-10): descriptive outcomes to 12 years post-injury.
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Derrett, Sarah, Owen, Helen E., Barson, David, Maclennan, Brett, Samaranayaka, Ari, Harcombe, Helen, and Wyeth, Emma H.
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WOUNDS & injuries ,RESEARCH funding ,DISABILITY evaluation ,QUESTIONNAIRES ,HOSPITAL care ,EVALUATION of medical care ,DESCRIPTIVE statistics ,LONGITUDINAL method ,QUALITY of life ,RESEARCH methodology ,COMPARATIVE studies ,PEOPLE with disabilities ,WELL-being - Published
- 2024
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12. Descriptive exploration of overdose codes in hospital and emergency department discharge data to inform development of drug overdose morbidity surveillance indicator definitions in ICD-10-CM.
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Tyndall Snow, Leigh M., Hall, Katelyn E., Custis, Cody, Rosenthal, Allison L., Pasalic, Emilia, Nechuta, Sarah, Davis, James W., Jacquemin, Bretta Jane, Jagroep, Sherani R., Rock, Peter, Contreras, Elyse, Gabella, Barbara A., and James, Katherine A.
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HOSPITALS ,HOSPITAL emergency services ,NOSOLOGY ,DRUG overdose ,RESEARCH methodology ,CROSS-sectional method ,DISEASES ,HOSPITAL care ,DESCRIPTIVE statistics ,EPIDEMIOLOGICAL research - Published
- 2021
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13. Long term outcomes of metabolic/bariatric surgery in adults.
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Courcoulas, Anita P., Daigle, Christopher R., and Arterburn, David E.
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BARIATRIC surgery ,METABOLIC disorders ,RISK assessment ,CONTINUING education units ,LIFESTYLES ,GASTRECTOMY ,CARDIOVASCULAR diseases ,PATIENT safety ,LONG-term health care ,HOSPITAL care ,GLYCEMIC control ,TREATMENT effectiveness ,DECISION making in clinical medicine ,CHRONIC diseases ,TYPE 2 diabetes ,QUALITY of life ,CHILDHOOD obesity ,TUMORS ,COVID-19 ,GASTRIC bypass ,DISEASE risk factors ,ADULTS - Published
- 2024
14. Hospital admissions for acute myocardial infarction before and after implementation of a comprehensive smoke-free policy in Uruguay.
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Sebrié, Ernesto Marcelo, Sandoya, Edgardo, Hyland, Andrew, Bianco, Eduardo, Glantz, Stanton A., and Cummings, K. Michael
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SMOKING laws ,CONFIDENCE intervals ,HOSPITAL care ,MYOCARDIAL infarction ,RESEARCH funding ,SMOKING cessation ,TIME series analysis ,MULTIPLE regression analysis ,DATA analysis software ,DESCRIPTIVE statistics - Abstract
Background Stimulated by the WHO Framework Convention on Tobacco Control, many countries in Latin America adopted comprehensive smoke-free policies. In March 2006, Uruguay became the first Latin American country to adopt 100% smoke-free national legislation, which ended smoking in all indoor public places and workplaces, including restaurants and bars. The objective of this study was to evaluate trends in hospital admissions for cardiovascular disease 2 years before and 2 years after the policy was implemented in Uruguay. Methods Reports of hospital admissions for acute myocardial infarction (AMI) (International Classification of Disease-10 I21) from 37 hospitals (79% of all hospital admissions in the country), representing the period 2 years before and 2 years after the adoption of a nationwide smoke-free policy in Uruguay (between 1 March 2004 and 29 February 2008), were reviewed. A time series analysis was undertaken to compare the average monthly number of events of hospital admission for AMI before and after the smoke-free law. Results A total of 7949 hospital admissions for AMI were identified during the 4-year study period. Two years after the smoke-free policy was enacted, hospital admissions for AMI fell by 22%. The same pattern and roughly the same magnitude of reduction in AMI admissions were observed for patients seen in public and private hospitals, men, women and people aged 40e65 years and older than 65 years. Conclusions The national smoke-free policy implemented in Uruguay in 2006 was associated with a significant reduction in hospital admissions for AMI. [ABSTRACT FROM AUTHOR]
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- 2013
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15. The costs of smoking in Vietnam: the case of inpatient care.
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Ross, Hana, Dang Vu Trung, and Vu Xuan Phu
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EXTERNALITIES ,SMOKING ,HOSPITAL care ,GROSS domestic product - Abstract
Objective: To estimate the social costs of smoking related to inpatient care in Vietnam using 2005 data. Design: The cost of illness as a result of hospitalisation for three major smoking-related diseases combined with the prevalence-based approach to obtain the costs of smoking in Vietnam for inpatient care. Main outcome measure: Smoking-attributable costs of inpatient care for lung cancer, chronic obstructive pulmonary disease (COPD), and ischaemic heart disease. Results: The total cost of inpatient health care caused by smoking in Vietnam reached at least 1 161 829 million Vietnamese dollars ($VN) (or $US77.5 million) in 2005. This represents about 0.22% of Vietnam gross domestic product (GDP) and 4.3% of total healthcare expenditure. The majority of these expenses are related to COPD treatment ($VN1 033 541 million or $US68.9 million per year) followed by lung cancer ($VN78 143 million, or $US5.2 million per year) and ischaemic disease ($VN50 145 million, or $US3.3 million per year). The government directly finances about 51% of these costs. The rest is financed either by households (34%) or by the insurance sector (15%). Conclusions: The social costs of smoking in Vietnam as the percentage of GDP is lower compared to estimates from high-income countries. The true costs would be substantially higher if all smoking-related diseases, outpatient care and mortality-related costs are included. More research is needed to augment the estimates presented in this paper. [ABSTRACT FROM AUTHOR]
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- 2007
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16. Factors affecting the likelihood of reporting road crashes resulting in medical treatment to the police.
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Loo, B. P. Y. and Tsui, K. I.
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TRAFFIC accidents ,POLICE reports ,TRANSPORTATION accidents ,COMMUNICATION in police administration ,HOSPITAL care - Abstract
Objective: This paper aims to determine the percentage of road crashes resulting in injuries requiring hospital care that are reported to the police and to identify factors associated with reporting such crashes to the police. Design: The data of one of two hospitals in the Road Casualty Information System were matched with the police's Traffic Accident Database System. Factors affecting the police-reporting rate were examined at two levels: the different reporting rates among subgroups examined and tested with x
2 tests; and multiple explanatory factors were scrutinised with a logistic regression model to arrive at the odds ratios to reflect the probability of police-reporting among subgroups. Results: The police-reporting rate was estimated to be 57.5-59.9%. In particular, under-reporting among children (reporting rate=33.6%) and cyclists (reporting rate=33.0%) was notable. Discussion: Accurate and reliable road crash data are essential for unveiling the full-scale and nature of the road safety problem. The police crash database needs to be supplemented by other data. In particular, any estimation about the social costs of road crashes must recognise the under-reporting problem. The large number of injuries not reflected in the police crash database represents a major public health issue that should be carefully examined. [ABSTRACT FROM AUTHOR]- Published
- 2007
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17. Hospitalisations from birth to 5 years in a population cohort of Western Australian children with intellectual disability.
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Williams, K., Leonard, H., Tursan d'Espaignet, E., Colvin, L., Slack-Smith, L., and Stanley, F.
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DEVELOPMENTAL disabilities ,HOSPITAL care ,AUTISM ,MEDICAL care ,PEOPLE with intellectual disabilities - Abstract
Aims: To describe the hospitalisation history in the first five years of life for all children born in Western Australia (WA) between 1983 and 1992 and diagnosed with intellectual disability (ID). Methods: Unit record linkage of the WA Midwives Collection, WA Intellectual Disability Database, and the WA Hospital Morbidity Dataset provided the population database of WA born children with and without ID. Affected children were divided into those co-affected with autism spectrum disorders (ASD), and those whose ID had or had no known biomedical cause. Those without a biomedical cause were further subdivided into mild-moderate and severe categories. Results: On average, ID affected children were more likely than non-affected children to be admitted to hospital (RR: 1.64; 95% CI 1.6 to 1.7), on more occasions (5.3 versus 2.2 admissions), for longer (29.6 versus 8.3 days), and for a larger range of clinical diagnoses. The only exception was the group of children co-diagnosed with ASD whose hospitalisation profile resembled more that of non-affected children. Conclusions: This total population study is unique because of the availability of the system of linkable population registers and administrative health databases in WA. The results indicated that this vulnerable population of children with ID has substantial medical needs. This paper points to the need for authorities to develop supportive programmes for this population especially in the current climate of de-medicalisation of ID. More research is not only needed on the welfare of the affected children but also on the impact of the substantial medical and other needs of affected children on the rest of their immediate and extended families. [ABSTRACT FROM AUTHOR]
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- 2005
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18. Exposure-response associations between chronic exposure to fine particulate matter and risks of hospital admission for major cardiovascular diseases: population based cohort study.
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Yaguang Wei, Yijing Feng, Yazdi, Mahdieh Danesh, Kanhua Yin, Castro, Edgar, Shtein, Alexandra, Xinye Qiu, Peralta, Adjani A., Coull, Brent A., Dominici, Francesca, and Schwartz, Joel D.
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PARTICULATE matter ,CARDIOVASCULAR diseases risk factors ,CONFIDENCE intervals ,RISK assessment ,HOSPITAL care ,DESCRIPTIVE statistics ,RESEARCH funding ,ENVIRONMENTAL exposure ,LONGITUDINAL method - Published
- 2024
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19. Association between high-sensitivity cardiac troponin I and fall-related hospitalisation in women aged over 70 years.
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Gebre, Abadi Kahsu, Sim, Marc, Via, Jack Dalla, Smith, Cassandra, Rodriguez, Alexander J., Hodgson, Jonathan M., Bondonno, Catherine P., Wai Lim, Byrnes, Elizabeth, Thompson, Peter R., Prince, Richard L., and Lewis, Joshua R.
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TROPONIN I ,CARDIOVASCULAR diseases ,HOSPITAL care ,MEDICAL sciences - Published
- 2024
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20. Did the Acute Frailty Network improve outcomes for older people living with frailty? A staggered difference-in-difference panel event study.
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Street, Andrew, Maynou, Laia, and Conroy, Simon
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LENGTH of stay in hospitals ,FRAIL elderly ,CONFIDENCE intervals ,PATIENTS ,REGRESSION analysis ,NATIONAL health services ,HOSPITAL admission & discharge ,T-test (Statistics) ,PSYCHOSOCIAL factors ,QUALITY of life ,HOSPITAL care ,RESEARCH funding ,DISCHARGE planning ,LONGITUDINAL method - Abstract
Objectives To evaluate whether the Acute Frailty Network (AFN) was more effective than usual practice in supporting older people living with frailty to return home from hospital sooner and healthier. Design Staggered difference- in- difference panel event study allowing for differential effects across intervention cohorts. Setting All English National Health Service (NHS) acute hospital sites. Participants All 1 410 427 NHS patients aged 75+ with high frailty risk who had an emergency hospital admission to acute, general or geriatric medicine departments between 1 January 2012 and 31 March 2019. Intervention Membership of the AFN, a quality improvement collaborative designed to support acute hospitals in England deliver evidence- based care for older people with frailty. 66 hospital sites joined the AFN in six sequential cohorts, the first starting in January 2015, the sixth in May 2018. Usual care was delivered in the remaining 248 control sites. Main outcome measures Length of hospital stay, in- hospital mortality, institutionalisation, hospital readmission. Results No significant effects of AFN membership were found for any of the four outcomes nor were there significant effects for any individual cohort. Conclusions To realise its aims, the AFN might need to develop better resourced intervention and implementation strategies. [ABSTRACT FROM AUTHOR]
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- 2023
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21. The hospitalisation of death: should more people die at home?
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Bowling, A
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DEATH ,FAMILIES ,HOME nursing ,HOSPITAL care ,HOUSING ,TERMINAL care - Abstract
With the increase in the proportion of hospital deaths there is increasing debate about appropriateness of place of death. Death should be a family affair but is increasingly hidden from public view. In contrast to those who die at home, most of those who die in hospital die alone with no relatives or friends with them. Husbands and wives are less likely to have the opportunity to say 'goodbye' to their dying spouses. As people become less familiar with death they may increasingly assume that the terminally ill are better cared for in hospital. However, this need not be the case. Most people want to die at home, most do not for social rather than medical reasons. It is not the illness itself which leads to hospital admission in many cases but its duration and nature--and the type of burden it places on relatives. Although home care should be encouraged where possible, no amount of exhortation to the family or to the dying person of the advantages of home care can disguise the fact that demand for domiciliary services is greater than is now being provided. The paper is based on one read to a London Medical Group Symposium. [ABSTRACT FROM PUBLISHER]
- Published
- 1983
22. Emergency hospital admissions for respiratory disorders attributable to summer time ozone episodes in Great Britain.
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Stedman, John R., Anderson, H. Ross, Atkinson, Richard W., Maynard, Robert L., Stedman, J R, Anderson, H R, Atkinson, R W, and Maynard, R L
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AIR pollution ,ASTHMA ,COMPARATIVE studies ,ENVIRONMENTAL monitoring ,HOSPITAL care ,RESEARCH methodology ,MEDICAL cooperation ,MEDICAL emergencies ,OZONE ,RESEARCH ,SUNSHINE ,ENVIRONMENTAL exposure ,EVALUATION research ,RELATIVE medical risk - Abstract
Background: There is accumulating evidence from various countries, including the UK, that ground level ozone concentrations are associated with increased daily hospital admissions for respiratory diseases. This paper estimates the impact of ozone episodes on daily hospital admissions for respiratory disease in Great Britain by combining locally based exposure-response relationships with mapped estimates of ozone exposure for the population in the summers of 1993 and 1995.Methods: For the given years the available ozone measurements were used to construct maps of ozone concentrations for each day. The population exposed to a given concentration of ozone on a particular day was calculated from census data using a geographical information system. The additional hospital admissions for respiratory disease were then estimated using a regression coefficient for London.Results: It is estimated that 0.10% (a total of 184) and 0.35% (a total of 643) of hospital admissions for respiratory disorders during the summers of 1993 and 1995, respectively, can be attributed to levels of ozone above 50 ppb (the recommended air quality standard for the UK). A sensitivity analysis for 1995 found that, if no threshold is assumed, the estimate is increased by about twenty fold (6% of admissions attributable).Conclusions: The additional hospital admissions for respiratory disease attributable to ozone are very small in both absolute and relative terms if a threshold of 50 ppb is assumed, but this estimate is very sensitive to threshold assumptions. [ABSTRACT FROM AUTHOR]- Published
- 1997
23. Risk factors for recurrent emergency department visits for asthma.
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Dales, R E, Schweitzer, I, Kerr, P, Gougeon, L, Rivington, R, and Draper, J
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ASTHMA treatment ,PSYCHOLOGY of asthma ,DRUG therapy for asthma ,ADRENOCORTICAL hormones ,DISEASES ,HOSPITAL care ,HOSPITAL emergency services ,LONGITUDINAL method ,MEDICAL care use ,TREATMENT effectiveness ,IMPACT of Event Scale - Abstract
Background: Patients presenting with asthma to emergency departments have lost control of their disease, have significant airways obstruction, and frequently require admission to hospital. Although even one visit is not desirable, there is a more disturbing subgroup who repeatedly visit the emergency department.Methods: To investigate the reasons for multiple emergency visits, a questionnaire was given to 448 consecutive patients presenting to the two largest adult emergency departments in Ottawa, Canada between November 1989 and April 1991. Within this cohort, those who had made at least three visits in the past year were compared with controls (only one visit in the past year).Results: Although inhaled corticosteroid use increased with multiple visits (indicating increased asthma severity), only 60% of those visiting at least three times in the past year were taking inhaled corticosteroids. Chronic undermedication relative to disease severity was apparent among the cases. The number of visits was associated with nocturnal asthma on a regular basis, work and school absenteeism, frequent visits to their regular physician, and frequent admissions to hospital. Visits were not related to psychological health, environmental allergens/irritants, or lack of perceived asthma severity.Conclusions: The recommendations of current asthma guidelines are not reaching these patients. The issue of translating guidelines from paper to practice must be addressed before highly effective medications can have an important impact on the frequency of emergency department visits. [ABSTRACT FROM AUTHOR]- Published
- 1995
24. Asthma hospitalisations and heat exposure in England: a case–crossover study during 2002–2019.
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Konstantinoudis, Garyfallos, Minelli, Cosetta, Yu Lam, Holly Ching, Fuertes, Elaine, Ballester, Joan, Davies, Bethan, Maria Vicedo-Cabrera, Ana, Gasparrini, Antonio, and Blangiardo, Marta
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HEAT stroke ,ASTHMA ,WHEEZE ,HOSPITAL care - Published
- 2023
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25. Nicotine replacement therapy 'gift cards' for hospital inpatients who smoke: a prospective before-and-after controlled pilot evaluation.
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Mullen, Kerri A., Walker, Kathryn L., Noble, Shireen, Pritchard, Gillian, Garg, Aditi, Martin, Natalie, Pipe, Andrew L., and Reid, Robert D.
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PILOT projects ,HOSPITALS ,SMOKING cessation ,GIFT giving ,RESEARCH methodology ,PHARMACOLOGY ,MOTIVATION (Psychology) ,PATIENT satisfaction ,COMPARATIVE studies ,SURVEYS ,NICOTINE replacement therapy ,HOSPITAL care ,RESEARCH funding ,STATISTICAL sampling ,ODDS ratio ,LONGITUDINAL method - Published
- 2023
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26. Antitubercular drug-induced violent suicide of a hospitalised patient.
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Behera, C., Krishna, Karthik, and Singh, H. R.
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DRUG therapy for tuberculosis ,ANTITUBERCULAR agents ,HOSPITAL care ,PSYCHOSES ,SUICIDE ,VIOLENCE - Abstract
We present a case where a young adult male, on treatment for multidrug-resistance tuberculosis (MDR-TB), developed drug-induced psychosis. The psychiatric symptoms were ascribed to the anti-TB drug and were duly withdrawn by the treating doctors and supplemented with other drugs. However, the victim continued to have psychiatric symptoms and committed suicide in the hospital. He ended his life in a violent manner by stabbing and cutting himself with a kitchen knife. The case is briefly reported in this paper with a discussion on anti-TB drug-induced psychiatric effects leading to suicide. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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27. Hospital admissions for acute myocardial infarction before and after implementation of a comprehensive smoke-free policy in Uruguay: experience through 2010.
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Marcelo Sebrié, Ernesto, Sandoya, Edgardo, Bianco, Eduardo, Hyland, Andrew, Cummings, K. Michael, and Glantz, Stanton A.
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MYOCARDIAL infarction ,CORONARY heart disease prevention ,SMOKING laws ,CONFIDENCE intervals ,HOSPITAL care ,RESEARCH funding ,MULTIPLE regression analysis ,RELATIVE medical risk ,HUMAN services programs ,PRE-tests & post-tests ,DATA analysis software ,DESCRIPTIVE statistics - Abstract
Background Comprehensive smoke-free laws have been followed by drops in hospitalisations for acute myocardial infarction (AMI), including in a study with 2 years follow-up for such a law in Uruguay. Methods Multiple linear and negative binomial regressions for AMI admissions (ICD-10 code 121) from 37 hospitals for 2 years before and 4 years after Uruguay implemented a 100% nationwide smoke-free law. Results Based on 11 135 cases, there was a significant drop of −30.9 AMI admissions/month (95% CI −49.8 to −11.8, p=0.002) following implementation of the smoke-free law. The effect of the law did not increase or decrease over time following implementation (p=0.234). This drop represented a 17% drop in AMI admissions following the law (IRR=0.829, 95% CI 0.743 to 0.925, p=0.001). Conclusions Adding two more years of follow-up data confirmed that Uruguay's smoke-free law was followed by a substantial and sustained reduction in AMI hospitalisations. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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28. Mixed-methods study examining family carers' perceptions of the relationship between intrahospital transitions and patient readiness for discharge.
- Author
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Bristol, Alycia A., Elmore, Catherine E., Weiss, Marianne E., Barry, Lisa A., Iacob, Eli, Johnson, Erin P., and Wallace, Andrea S.
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FAMILIES & psychology ,CAREGIVER attitudes ,PATIENT aftercare ,STATISTICS ,RESEARCH methodology ,ONE-way analysis of variance ,INTERVIEWING ,QUANTITATIVE research ,T-test (Statistics) ,PEARSON correlation (Statistics) ,HOSPITAL care ,DESCRIPTIVE statistics ,CHI-squared test ,RESEARCH funding ,DECISION making in clinical medicine ,DATA analysis ,LOGISTIC regression analysis ,DISCHARGE planning - Abstract
Introduction Intrahospital transitions (IHTs) represent movements of patients during hospitalisation. While transitions are often clinically necessary, such as a transfer from the emergency department to an intensive care unit, transitions may disrupt care coordination, such as discharge planning. Family carers often serve as liaisons between the patient and healthcare professionals. However, carers frequently experience exclusion from care planning during IHTs, potentially decreasing their awareness of patients' clinical status, postdischarge needs and carer preparation. The purpose of this study was to explore family carers' perceptions about IHTs, patient and carer ratings of patient discharge readiness and carer self-perception of preparation to engage in at home care. Methods Sequential, explanatory mixed-methods study involving retrospective analysis of hospital inpatients from a parent study (1R01HS026248; PI Wallace) for whom patient and family carer Readiness for Hospital Discharge Scale (RHDS) score frequency of IHTs and patient and caregiver characteristics were available. Maximum variation sampling was used to recruit a subsample of carers with diverse backgrounds and experiences for the participation in semistructured interviews to understand their views of how IHTs influenced preparation for discharge. Results Of discharged patients from July 2020 to April 2021, a total of 268 had completed the RHDS and 23 completed the semistructured interviews. Most patients experienced 0-2 IHTs and reported high levels of discharge readiness. During quantitative analysis, no association was found between IHTs and patients' RHDS scores. However, carers' perceptions of patient discharge readiness were negatively associated with increased IHTs. Moreover, non-spouse carers reported lower RHDS scores than spousal carers. During interviews, carers shared barriers experienced during IHTs and discussed the importance of inclusion during discharge care planning. Conclusions IHTs often represent disruptive events that may influence carers' understanding of patient readiness for discharge to home and, thus, their own preparation for discharge. Further consideration is needed regarding how to support carers during IHT to facilitate high-quality discharge planning. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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29. Hospital admissions linked to SARS-CoV-2 infection in children and adolescents: cohort study of 3.2 million first ascertained infections in England.
- Author
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Wilde, Harrison, Tomlinson, Christopher, Mateen, Bilal A., Selby, David, Kanthimathinathan, Hari Krishnan, Ramnarayan, Padmanabhan, Du Pre, Pascale, Johnson, Mae, Pathan, Nazima, Gonzalez-Izquierdo, Arturo, Lai, Alvina G., Gurdasani, Deepti, Pagel, Christina, Denaxas, Spiros, Vollmer, Sebastian, and Brown, Katherine
- Subjects
CROSS infection prevention ,LENGTH of stay in hospitals ,COVID-19 ,PATIENTS ,PUBLIC health ,HOSPITAL admission & discharge ,HOSPITAL care ,ELECTRONIC health records ,LONGITUDINAL method ,CHILDREN ,ADOLESCENCE - Published
- 2023
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30. How do hospital inpatients conceptualise patient safety? A qualitative interview study using constructivist grounded theory.
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Barrow, Emily, Lear, Rachael A., Morbi, Abigail, Long, Susannah, Darzi, Ara, Mayer, Erik, and Archer, Stephanie
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FRIENDSHIP ,ACADEMIC medical centers ,CAREGIVERS ,GROUNDED theory ,SOCIAL constructionism ,RESEARCH methodology ,MATHEMATICAL models ,CONCEPT mapping ,INTERVIEWING ,CONCEPTUAL structures ,PATIENTS' attitudes ,QUALITATIVE research ,COMPARATIVE studies ,EXPERIENCE ,HOSPITAL care ,THEORY ,RESEARCH funding ,CLUSTER analysis (Statistics) ,FAMILY relations ,PATIENT-professional relations ,THEMATIC analysis ,PATIENT safety ,CONCEPTS - Abstract
Background Efforts to involve patients in patient safety continue to revolve around professionally derived notions of minimising clinical risk, yet evidence suggests that patients hold perspectives on patient safety that are distinct from clinicians and academics. This study aims to understand how hospital inpatients across three different specialties conceptualise patient safety and develop a conceptual model that reflects their perspectives. Methods A qualitative semi- structured interview study was conducted with 24 inpatients across three clinical specialties (medicine for the elderly, elective surgery and maternity) at a large central London teaching hospital. An abbreviated form of constructivist grounded theory was employed to analyse interview transcripts. Constant comparative analysis and memo- writing using the clustering technique were used to develop a model of how patients conceptualise patient safety. Results While some patients described patient safety using terms consistent with clinical/academic definitions, patients predominantly conceptualised patient safety in the context of what made them 'feel safe'. Patients' feelings of safety arose from a range of care experiences involving specific actors: hospital staff, the patient, their friends/family/carers, and the healthcare organisation. Four types of experiences contributed to how patients conceptualise safety: actions observed by patients; actions received by patients; actions performed by patients themselves; and shared actions involving patients and other actors in their care. Conclusions Our findings support the need for a patient safety paradigm that is meaningful to all stakeholders, incorporating what matters to patients to feel safe in hospital. Additional work should explore and test how the proposed conceptual model can be practically applied and implemented to incorporate the patient conceptualisation of patient safety into everyday clinical practice. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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- View/download PDF
31. Predictors and population health outcomes of persistent high GP turnover in English general practices: a retrospective observational study.
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Parisi, Rosa, Yiu- Shing Lau, Bower, Peter, Checkland, Katherine, Rubery, Jill, Sutton, Matt, Giles, Sally J., Esmail, Aneez, Spooner, Sharon, and Kontopantelis, Evangelos
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EVALUATION of medical care ,KEY performance indicators (Management) ,SCIENTIFIC observation ,HEALTH services accessibility ,CONFIDENCE intervals ,FAMILY medicine ,MULTIPLE regression analysis ,RETROSPECTIVE studies ,PATIENT satisfaction ,DISEASES ,LABOR turnover ,RISK assessment ,CONTINUUM of care ,NATIONAL health services ,CLINICAL medicine ,HOSPITAL care ,DESCRIPTIVE statistics ,EMERGENCY medical services ,RESEARCH funding ,POPULATION health ,STATISTICAL models ,MEDICAL appointments ,DATA analysis software ,ODDS ratio - Abstract
Objective English primary care faces significant challenges, including 'persistent high turnover' of general practitioners (GPs) in some partnerships. It is unknown whether there are specific predictors of persistent high turnover and whether it is associated with poorer population health outcomes. Design A retrospective observational study. Methods We linked workforce data on individual GPs to practice- level data from Hospital Episode Statistics and the GP Patient Survey (2007--2019). We classified practices as experiencing persistent high turnover if more than 10% of GPs changed in at least 3 consecutive years. We used multivariable logistic or linear regression models for panel data with random effects to identify practice characteristics that predicted persistent high turnover and associations of practice outcomes (higher emergency hospital use and patient experience of continuity of care, access to care and overall patient satisfaction) with persistent high turnover. Results Each year, 6% of English practices experienced persistent high turnover, with a maximum of 9% (688/7619) in 2014. Larger practices, in more deprived areas and with a higher morbidity burden were more likely to experience persistent high turnover. Persistent high turnover was associated with 1.8 (95% CI 1.5 to 2.1) more emergency hospital attendances per 100 patients, 0.1 (95% CI 0.1 to 0.2) more admissions per 100 patients, 5.2% (95% CI -5.6% to -4.9%) fewer people seeing their preferred doctor, 10.6% (95% CI-11.4% to -9.8%) fewer people reporting obtaining an appointment on the same day and 1.3% (95% CI -1.6% to -1.1%) lower overall satisfaction with the practice. Conclusions Persistent high turnover is independently linked to indicators of poorer service and health outcomes. Although causality needs to be further investigated, strategies and policies may be needed to both reduce high turnover and support practices facing challenges with high GP turnover when it occurs. [ABSTRACT FROM AUTHOR]
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- 2023
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- View/download PDF
32. Risk prediction of covid-19 related death or hospital admission in adults testing positive for SARS-CoV-2 infection during the omicron wave in England (QCOVID4): cohort study.
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Hippisley-Cox, Julia, Khunti, Kamlesh, Sheikh, Aziz, Nguyen-Van-Tam, Jonathan S., and Coupland, Carol A. C.
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PATIENT aftercare ,COVID-19 ,GENETIC mutation ,CONFIDENCE intervals ,COVID-19 vaccines ,CALIBRATION ,IDENTIFICATION ,DIGITAL health ,PATIENTS ,RISK assessment ,TREATMENT effectiveness ,SEX distribution ,HOSPITAL care ,RESEARCH funding ,COVID-19 testing ,ALGORITHMS ,LONGITUDINAL method ,DOSE-response relationship in biochemistry - Published
- 2023
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33. Measles, mumps, and rubella vaccine at age 6 months and hospitalisation for infection before age 12 months: randomised controlled trial.
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Zimakoff, Anne Cathrine, Jensen, Andreas, Vittrup, Dorthe Maria, Hoppe Herlufsen, Emma, Sørensen, Jesper Kiehn, Malon, Michelle, Svensson, Jannet, and Graff Stensballe, Lone
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MEASLES prevention ,RUBELLA ,CONFIDENCE intervals ,IMMUNIZATION of children ,RANDOMIZED controlled trials ,HOSPITAL care ,RESEARCH funding ,BLIND experiment ,DESCRIPTIVE statistics ,MMR vaccines ,MUMPS ,DATA analysis software ,PROPORTIONAL hazards models ,CHILDREN - Published
- 2023
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34. BMA AFFAIRS.
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PATIENTS , *HOSPITAL medical staff , *HOSPITAL care - Abstract
Focuses on issues related to the proposed white paper 'Working for Patients' in Great Britain. Citation of the aims of the paper; Discussion of British Medical Association with the secretary of state and the Department of Health regarding the paper; Opposition of several senior hospital medical staff for the establishment of self-governing hospitals.
- Published
- 1989
35. Effect of a multifaceted antibiotic stewardship intervention to improve antibiotic prescribing for suspected urinary tract infections in frail older adults (ImpresU): pragmatic cluster randomised controlled trial in four European countries.
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Hartman, Esther A. R., de Pol, Alma C. van, Heltveit-Olsen, Silje Rebekka, Lindbæk, Morten, Høye, Sigurd, Lithén, Sara Sofia, Sundvall, Pär-Daniel, Sundvall, Sofia, Arnljots, Egill Snaebjörnsson, Gunnarsson, Ronny, Kowalczyk, Anna, Godycki-Cwirko, Maciek, Platteel, Tamara N., Groen, Wim G., Monnier, Annelie A., Zuithoff, Nicolaas P., Verheij, Theo J. M., and Hertogh, Cees M. P. M.
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ANTIBIOTICS ,ANTIMICROBIAL stewardship ,EVALUATION of human services programs ,URINARY tract infections ,PATIENTS ,INAPPROPRIATE prescribing (Medicine) ,RANDOMIZED controlled trials ,HOSPITAL admission & discharge ,ACTION research ,HOSPITAL care ,RESEARCH funding ,STATISTICAL sampling ,DISEASE complications ,OLD age - Published
- 2023
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36. Primary care-based smoking cessation treatment and subsequent healthcare service utilisation: a matched cohort study of smokers using linked administrative healthcare data.
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Baliunas, Dolly, Selby, Peter, de Oliveira, Claire, Kurdyak, Paul, Rosella, Laura, Zawertailo, Laurie, Longdi Fu, and Sutradhar, Rinku
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SMOKING cessation ,OUTPATIENT medical care ,HOSPITAL emergency services ,EVALUATION of human services programs ,CONFIDENCE intervals ,RETROSPECTIVE studies ,PRIMARY health care ,TREATMENT effectiveness ,MEDICAL care use ,COMPARATIVE studies ,HOSPITAL care ,DESCRIPTIVE statistics ,RESEARCH funding ,ODDS ratio ,LONGITUDINAL method ,COMORBIDITY ,EVALUATION - Published
- 2023
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37. Effect of asthma education on health outcomes in children: a systematic review.
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Wen-Yi Liu, Zhu Liduzi Jiesisibieke, Tao-Hsin Tung, Liu, Wen-Yi, Jiesisibieke, Zhu Liduzi, and Tung, Tao-Hsin
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ASTHMA prevention ,EVALUATION research ,HOSPITAL care ,HOSPITAL emergency services ,META-analysis ,FERRANS & Powers Quality of Life Index ,RESEARCH ,RESEARCH methodology ,COMPARATIVE studies ,IMPACT of Event Scale - Abstract
Background: It remains unknown whether child-oriented asthma education is associated with better health outcomes. This meta-analysis investigated the effects of asthma education on hospitalisation and emergency department and clinic visits.Methods: We searched the Cochrane Library, PubMed and EMBASE for relevant studies from inception to 4 July 2021, and selected studies that reported hospitalisation or emergency department or clinic visits as outcomes. The participants were only children. Two authors independently selected the studies, assessed the quality of the included studies and retrieved the data. A third senior author was engaged to resolve disagreements. Fifteen longitudinal studies were included for the systematic review and meta-analysis. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 was used as the standard of reporting (PRISMA registration ID is 284509).Findings: Compared with the control group, the asthma education group had 54% lower hospitalisation risk (95% CI 0.32 to 0.66), and 31% lower emergency department visit risk (95% CI 0.59 to 0.81). Sensitivity analysis showed that the asthma education group had a reduced clinic visit risk (risk ratio (RR)=0.80, 95% CI 0.67 to 0.97). Subgroup analysis showed that asthma education involving both children and parents/guardians was associated with fewer hospitalisations (RR=0.38, 95% CI 0.24 to 0.59) and emergency department visits (RR=0.69, 95% CI 0.57 to 0.83). Asthma education in hospitals or non-hospitals can reduce the risk of hospitalisation and emergency department visits. However, only education in the hospitals was associated with the reduction of clinical visits (RR=0.45, 95% CI 0.22 to 0.92).Interpretation: Education is effective for controlling asthma, especially for reducing hospitalisation and emergency department and clinic visits. Education involving both children and parents/guardians is more effective than that involving only children. The setting of asthma education does not impact its effect to a large extent. [ABSTRACT FROM AUTHOR]- Published
- 2022
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38. Impact of community asymptomatic rapid antigen testing on covid-19 related hospital admissions: synthetic control study.
- Author
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Xingna Zhang, Barr, Ben, Green, Mark, Hughes, David, Ashton, Matthew, Charalampopoulos, Dimitrios, García-Fiñana, Marta, and Buchan, Iain
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COVID-19 ,SARS-CoV-2 ,CONFIDENCE intervals ,POST-acute COVID-19 syndrome ,PATIENTS ,COMMUNITY health services ,PUBLIC health ,HOSPITAL admission & discharge ,COMPARATIVE studies ,HOSPITAL care ,DESCRIPTIVE statistics ,COVID-19 testing ,SOCIODEMOGRAPHIC factors ,STAY-at-home orders ,ISOLATION (Hospital care) ,PATIENT self-monitoring - Published
- 2022
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39. Ambient heat exposure and COPD hospitalisations in England: a nationwide case-crossover study during 2007-2018.
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Konstantinoudis, Garyfallos, Minelli, Cosetta, Maria Vicedo-Cabrera, Ana, Ballester, Joan, Gasparrini, Antonio, and Blangiardo, Marta
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HOSPITAL statistics ,HEAT stroke ,CHRONIC obstructive pulmonary disease ,HOSPITAL care - Published
- 2022
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40. Comparing antibiotic prescribing between clinicians in UK primary care: an analysis in a cohort study of eight different measures of antibiotic prescribing.
- Author
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Van Staa, Tjeerd, Yan Li, Gold, Natalie, Chadborn, Tim, Welfare, William, Ashcroft, Victoria PalinDarren M., and Bircher, Joanna
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BACTERIAL disease complications ,ANTIBIOTICS ,STATISTICS ,URINARY tract infections ,AGE distribution ,ACQUISITION of data ,RESPIRATORY infections ,PRIMARY health care ,COMPARATIVE studies ,RISK assessment ,SEX distribution ,DRUG prescribing ,MEDICAL records ,DESCRIPTIVE statistics ,MEDICAL referrals ,HOSPITAL care ,RESEARCH funding ,BACTERIAL diseases ,PHYSICIAN practice patterns ,DATA analysis ,DATA analysis software ,STATISTICAL models ,LONGITUDINAL method ,POISSON distribution - Abstract
Background There is a need to reduce antimicrobial uses in humans. Previous studies have found variations in antibiotic (AB) prescribing between practices in primary care. This study assessed variability of AB prescribing between clinicians. Methods Clinical Practice Research Datalink, which collects electronic health records in primary care, was used to select anonymised clinicians providing 500+ consultations during 2012--2017. Eight measures of AB prescribing were assessed, such as overall and incidental AB prescribing, repeat AB courses and extent of risk- based prescribing. Poisson regression models with random effect for clinicians were fitted. Results 6111 clinicians from 466 general practices were included. Considerable variability between individual clinicians was found for most AB measures. For example, the rate of AB prescribing varied between 77.4 and 350.3 per 1000 consultations; percentage of repeat AB courses within 30 days ranged from 13.1% to 34.3%; predicted patient risk of hospital admission for infection- related complications in those prescribed AB ranged from 0.03% to 0.32% (5th and 95th percentiles). The adjusted relative rate between clinicians in rates of AB prescribing was 5.23. Weak correlation coefficients (<0.5) were found between most AB measures. There was considerable variability in case mix seen by clinicians. The largest potential impact to reduce AB prescribing could be around encouraging risk- based prescribing and addressing repeat issues of ABs. Reduction of repeat AB courses to prescribing habit of median clinician would save 21 813 AB prescriptions per 1000 clinicians per year. Conclusions The wide variation seen in all measures of AB prescribing and weak correlation between them suggests that a single AB measure, such as prescribing rate, is not sufficient to underpin the optimisation of AB prescribing. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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41. Embracing carers: when will adult hospitals fully adopt the same practices as children's hospitals?
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Williams, Mark V. and Jing Li
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HOSPITALS ,CAREGIVER attitudes ,EVALUATION of medical care ,LEGAL status of caregivers ,PATIENT participation ,MEDICAL personnel ,PATIENT-centered care ,JOB involvement ,PATIENTS' attitudes ,PATIENTS' families ,FAMILY-centered care ,HOSPITAL care ,DECISION making ,PATIENT care ,DISCHARGE planning - Published
- 2023
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42. The weekend effect: now you see it, now you don't.
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McKee, Martin
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HOSPITAL care ,HOSPITAL admission & discharge ,WORKING hours ,PATIENTS ,PATIENT safety ,SERIAL publications ,TIME ,TREATMENT effectiveness ,STROKE patients - Abstract
The author reflects on the safety of hospitals at weekends in Great Britain. Topics covered include the development of hospital safety policies based on systematic and dispassionate assessment of evidence, the highlights of the article "Biases in detection of apparent 'weekend effect' on outcome with administrative coding data: population based study of stroke" published in the journal "The BMJ" on May 16, 2016, and other research studies relating to the hospital weekend effect.
- Published
- 2016
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43. Google shopping queries for vaping products, JUUL and IQOS during the E- cigarette, or Vaping, product use Associated Lung Injury (EVALI) outbreak.
- Author
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Leas, Eric C., Moy, Natalie H., Nobles, Alicia L., Ayers, John, Shu-Hong Zhu, and Purushothaman, Vidya
- Subjects
E-cigarette or vaping product use-associated lung injuries ,ELECTRONIC cigarettes ,ELECTRONIC commerce ,CONFIDENCE intervals ,LUNG diseases ,SEARCH engines ,SHOPPING ,DESCRIPTIVE statistics ,HOSPITAL care ,SMOKING ,TOBACCO products - Published
- 2022
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44. Clinical prediction models for mortality in patients with covid-19: external validation and individual participant data meta-analysis.
- Author
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de Jong, Valentijn M. T., Rousset, Rebecca Z., Antonio-Villa, Neftali Eduardo, Buenen, Arnoldus G., Van Calster, Ben, Bello-Chavolla, Omar Yaxmehen, Brunskill, Nigel J., Curcin, Vasa, Damen, Johanna A. A., Fernández-Chirino, Luisa, Ferrari, Davide, Free, Robert C., Gupta, Rishi K., Haldar, Pranabashis, Hedberg, Pontus, Korang, Steven Kwasi, Kurstjens, Steef, Kusters, Ron, Major, Rupert W., and Maxwell, Lauren
- Subjects
COVID-19 ,META-analysis ,CONFIDENCE intervals ,TERTIARY care ,HOSPITAL care ,DESCRIPTIVE statistics ,PREDICTION models ,DATA analysis software ,POLYMERASE chain reaction ,SECONDARY care (Medicine) - Published
- 2022
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45. Late clinical presentation of congenital adrenal hyperplasia in older children: findings from national paediatric surveillance.
- Author
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Knowles, Rachel L., Khalid, Javaria M., Oerton, Juliet M., Hindmarsh, Peter C., Kelnar, Christopher J., and Dezateux, Carol
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ADRENOGENITAL syndrome ,JUVENILE diseases ,PEDIATRICS ,HOSPITAL care ,DIAGNOSIS - Abstract
Objectives: To describe the clinical presentation and sequelae, including salt-wasting crises of newlydiagnosed congenital adrenal hyperplasia (CAH) in children aged over 1 year in a contemporary population without screening. To appraise the potential benefit of newborn screening for late-presenting CAH. Design: Active national surveillance undertaken in Great Britain prospectively from 2007-2009 through the British Paediatric Surveillance Unit. Setting: England, Wales and Scotland. Patients Children first presenting aged 1-15 years with clinical features of CAH and elevated 17-hydroxyprogesterone. Results: Fifty-eight children (26 [45%] boys) aged 1-15 years were reported; 50 (86%) had 21-hydroxylase deficiency. Diagnosis was precipitated by secondary sexual characteristics (n=38 [66%]; median age 5.8 [IQR] 4.8, 7.6) years, genital virilisation (8 girls; 3.2 [IQR 1.3, 7.3] years) or an affected sibling (n=8; 10.0 [IQR 7.4, 13.3] years). At least 33 (57%) children had advanced bone age and 13 (30%) were obese (body mass index ≥95th centile). No child had experienced a salt-wasting crisis. Conclusions: In Great Britain, 30 children aged 1-15 years present annually for the first time with CAH. Older children frequently manifest prematurely advanced epiphyseal and pubertal maturation and genital virilisation, which are often irreversible and likely to have long-lasting consequences for adult health and wellbeing. Almost one-third of affected children are obese before commencing steroid therapy. Newborn screening offers the potential to avoid serious clinical manifestations in older children with unrecognised CAH; however, it may also detect some children who would otherwise remain asymptomatic and for whom the benefit from treatment is uncertain. Conclusions: In Great Britain, 30 children aged 1-15 years present annually for the first time with CAH. Older children frequently manifest prematurely advanced epiphyseal and pubertal maturation and genital virilisation, which are often irreversible and likely to have long-lasting consequences for adult health and wellbeing. Almost one-third of affected children are obese before commencing steroid therapy. Newborn screening offers the potential to avoid serious clinical manifestations in older children with unrecognised CAH; however, it may also detect some children who would otherwise remain asymptomatic and for whom the benefit from treatment is uncertain. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
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46. Headache-related health resource utilisation in chronic and episodic migraine across six countries.
- Author
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Sanderson, Joanna C., Devine, Emily B., Lipton, Richard B., Bloudek, Lisa M., Varon, Sepideh F., Blumenfeld, Andrew M., Goadsby, Peter J., Buse, Dawn C., and Sullivan, Sean D.
- Subjects
HEADACHE treatment ,PUBLIC health ,MIGRAINE ,HOSPITAL care ,COMPARATIVE studies - Abstract
Objective: To describe headache-related health resource usage in chronic and episodic migraine across six countries. Methods: A web-based questionnaire eliciting data on several topics, including health resource usage, was administered to panellists with migraine from the USA, Canada, UK, Germany, France and Australia. Respondents were grouped into episodic and chronic migraine, based on reported headache phenotype and headache-day frequency. ORs were calculated, comparing usage in each country to that in the US, controlling for chronic versus episodic migraine and other factors. Results: Relative to the USA, the odds of visiting a provider for headache during the preceding 3 months were significantly higher in all countries, except Germany. Respondents in France were more likely to report having a provider they typically visited for headache-related care. The odds of visiting the emergency department for headache were significantly lower in France, the UK and Germany, and hospitalisation for headache was significantly more frequent in Canada and Australia. Respondents from all countries, except Canada, were more likely to report currently using a prescription-acute treatment, and those from France were more likely to report trying more than three acute treatments. Preventive treatment use did not differ significantly. Conclusions: Headache-related resource usage differed significantly between the USA and other countries. US respondents were generally less likely to report recent provider visits and use of prescription-acute treatments. They were more likely to report emergency department visits than in European countries, but less likely to report hospitalisation than in Canada and Australia. [ABSTRACT FROM AUTHOR]
- Published
- 2013
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47. Action indicators for injury prevention.
- Author
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MacKay, J. Morag, Macpherson, Alison K., Pike, Ian, Vincenten, Joanne, and McClure, Rod
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PREVENTION of injury ,HEALTH outcome assessment ,CHILD welfare ,HOSPITAL care ,PUBLIC health - Abstract
There is considerable confusion about the nature of indicators, their use in the injury field and surprisingly little discussion about these important tools. To date discussions of injury indicators have focused on the content and presentation of health outcome measures and on the dearth of data on exposure measures. Whereas these are valuable measures and assessing the optimal use of available routinely collected data in forming indicators is important, they do not provide sufficient information to support comprehensive prevention efforts, nor do they harness the full potential of indicators as tools to support prevention efforts. This paper provides an overview of the characteristics and uses of indicators for the field of injury prevention in order to make the case for action indicators and provide a framework for their appropriate use. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
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48. Reduction in hospital admissions for acute coronary syndrome after the successful implementation of 100% smoke-free legislation in Argentina: a comparison with partial smoking restrictions.
- Author
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Ferrante, D., Linetzky, B., Virgolini, M., Schoj, V., and Aeplberg, B.
- Subjects
PASSIVE smoking ,SMOKING laws ,ACUTE coronary syndrome ,CHI-squared test ,COMPARATIVE studies ,CONFIDENCE intervals ,HOSPITAL care ,REGRESSION analysis ,TIME series analysis ,MULTIPLE regression analysis ,DISEASE prevalence ,DESCRIPTIVE statistics ,PREVENTION - Abstract
Background: Several studies have shown a decrease in acute coronary syndrome (ACS) admissions after the implementation of 100% smoke-free legislation. However, no studies have been conducted in developing countries. Methods: We conducted a time series analysis of ACS hospital admissions in Santa Fe province and Buenos Aires city, Argentina. In 2006, Santa Fe implemented a 100% smoke-free law and Buenos Aires implemented a partial law with designated smoking areas and exceptions. Age-standardised ACS admissions rates were compared before and after the implementation of the laws in each district. Smoking prevalence, compliance with legislation and exposure to secondhandsmoke (SHS) was also assessed in both districts. Results: In Santa Fe an immediate decrease in ACS admissions was observed after implementation (2.5 admissions per 100 000, p¼0.03; 13% reduction), compared with no change in Buenos Aires city (rate ratio Santa Fe vs Buenos Aires: 0.74, 95% CI 0.63 to 0.86, p#0.001). In Santa Fe, the immediate effect was followed by a persistent decrease in admissions due to ACS (0.26 admissions per 100 000 per month). Smoking prevalence did not change significantly in either district during the same period. In both districts, there was a reduction in self-reported SHS exposure, with a trend towards lower exposure in Santa Fe province. No other comprehensive tobacco control interventions were implemented during the study period. Conclusions: A 100% smoke-free law was more effective than a partial restriction law in reducing ACS admissions. An immediate effect was followed by a sustained decrease in ACS admissions. Smoke-free initiatives can be also effective in decreasing acute coronary events in developing countries. [ABSTRACT FROM AUTHOR]
- Published
- 2012
- Full Text
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49. BReATHE interventions (Beating Regional Asthma Through Health Education)-an innovative approach to children's asthma care in the North East and North Cumbria, UK: an interventional study.
- Author
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Townshend, Jennifer Katherine, Hails, Sally, Levey, Ruth, DeZwart, Patty, McKean, Michael, and Moss, Samantha
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ASTHMA treatment ,HEALTH education ,ASTHMA ,NATIONAL health services ,HOSPITAL care - Abstract
To objective of this project was to reduce unplanned hospital admission rates in children related to asthma to the Newcastle upon Tyne Hospitals National Health Service Trust (NUTH).Multiple educational interventions were introduced both locally and regionally including: a collection of educational materials aimed at young people and families, schools, primary care and secondary care on the website www.beatasthma.co.uk; regional training days; a nurse-led one-stop clinic; a new pathway following an acute attendance to hospital with an asthma attack; a local asthma service and cascade training for schools.The primary outcome measure was reduction in unplanned hospital admission rates in children due to asthma to the NUTH.Results showed that admission rates had been increasing at a sustained rate of approximately 30% each year in the 3 years prior to our intervention. After the Beating Regional Asthma Through Health Education interventions, unplanned admissions to NUTH reduced by 29% and this reduction has been sustained for the last 3 years. This compares with a regional increase of 10% over the same time period.In conclusion, simple but effective educational interventions resulted in a significant and sustained reduction in unplanned asthma admissions to NUTH. Further work is underway to extend the reach of these interventions into primary care and schools. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
50. Occupation and COVID-19 diagnosis, hospitalisation and ICU admission among foreign-born and Swedish-born employees: a register-based study.
- Author
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Nwaru, Chioma Adanma, Santosa, Ailiana, Franzén, Stefan, and Nyberg, Fredrik
- Subjects
EMPLOYEE psychology ,INTENSIVE care units ,IMMIGRANTS ,CONFIDENCE intervals ,OCCUPATIONAL hazards ,HOSPITAL care ,DESCRIPTIVE statistics ,COVID-19 testing - Published
- 2022
- Full Text
- View/download PDF
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