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Your search keyword '"Schmeler, Kathleen"' showing total 28 results
Start Over Author "Schmeler, Kathleen" Publisher bmj
28 results on '"Schmeler, Kathleen"'

2. ConCerv: a prospective trial of conservative surgery for low-risk early-stage cervical cancer

Author

Schmeler, Kathleen M, primary, Pareja, Rene, additional, Lopez Blanco, Aldo, additional, Humberto Fregnani, Jose, additional, Lopes, Andre, additional, Perrotta, Myriam, additional, Tsunoda, Audrey T, additional, Cantú-de-León, David F, additional, Ramondetta, Lois M, additional, Manchana, Tarinee, additional, Crotzer, David R, additional, McNally, Orla M, additional, Riege, Martin, additional, Scambia, Giovanni, additional, Carvajal, Juan Manuel, additional, Di Guilmi, Julian, additional, Rendon, Gabriel J, additional, Ramalingam, Preetha, additional, Fellman, Bryan M, additional, Coleman, Robert L, additional, Frumovitz, Michael, additional, and Ramirez, Pedro T, additional

Published
2021
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6. The Capulana study: a prospective evaluation of cervical cancer screening using human papillomavirus testing in Mozambique

Author

Salcedo, Mila P, primary, Oliveira, Cristina, additional, Andrade, Viviane, additional, Mariano, Arlete A N, additional, Changule, Dércia, additional, Rangeiro, Ricardina, additional, Monteiro, Eliane C S, additional, Baker, Ellen, additional, Phoolcharoen, Natacha, additional, Varon, Melissa L, additional, Thomas, Joseph P, additional, Castle, Philip E, additional, Fregnani, Jose Humberto T G, additional, Schmeler, Kathleen M, additional, and Lorenzoni, Cesaltina, additional

Published
2020
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7. Tumor microbial diversity and compositional differences among women in Botswana with high-grade cervical dysplasia and cervical cancer

Author

Sims, Travis T, primary, Biegert, Greyson W G, additional, Ramogola-Masire, Doreen, additional, Ngoni, Kebatshabile, additional, Solley, Travis, additional, Ning, Matthew S, additional, El Alam, Molly B, additional, Mezzari, Melissa, additional, Petrosino, Joseph, additional, Zetola, Nicola M, additional, Schmeler, Kathleen M, additional, Colbert, Lauren E, additional, Klopp, Ann H, additional, and Grover, Surbhi, additional

Published
2020
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9. Telementoring in gynecologic oncology training: changing lives in Mozambique

Author

Moretti-Marques, Renato, primary, Salcedo, Mila Pontremoli, additional, Callegaro Filho, Donato, additional, Lopes, Andre, additional, Vieira, Marcelo, additional, Fontes Cintra, Geórgia, additional, Ribeiro, Magda, additional, Changule, Dércia, additional, Daud, Siro, additional, Rangeiro, Ricardina, additional, Baker, Ellen, additional, Lorenzoni, Cesaltina, additional, Fregnani, Jose Humberto Tavares Guerreiro, additional, and Schmeler, Kathleen M, additional

Published
2019
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13. Proceedings From the 1st International Conference "Current Concepts and Controversies in Gynecologic and Urologic Oncology"

Author

Matylevich, Olga, primary, Mavrichev, Sergey, additional, Pletnev, Andrei, additional, Evmenenko, Alesya, additional, Shevchuk, Aleksey, additional, Suslova, Valentina, additional, Taranenko, Sergey, additional, Dolomanova, Elena, additional, Rovsky, Dmitry, additional, Portyanko, Anna, additional, Brown, Jubilee, additional, Naumann, Robert Wendel, additional, Schmeler, Kathleen, additional, Plotkin, Anna, additional, Michaelson, Sophia, additional, Eiken, Mary, additional, Trimble, Edward, additional, and Randall, Thomas, additional

Published
2018
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14. Sister Society Meeting on Global Education Development and Collaboration: Meeting Report

Author

Chuang, Linus T., primary, Randall, Thomas C., additional, Denny, Lynette, additional, Johnston, Carolyn M., additional, Schmeler, Kathleen M., additional, Covens, Allan L., additional, Cibula, David, additional, Bookman, Michael A., additional, Rawal, Sudhir, additional, DePetrillo, Denny, additional, Nam, Joo-Hyun, additional, Goodman, Annekathryn, additional, Naik, Raj, additional, Manchanda, Ranjit, additional, Gaffney, David K., additional, Small, William, additional, Creutzberg, Carien, additional, Rattray, Carole, additional, Kesic, Vesna, additional, Paraja, René, additional, Eiken, Mary, additional, Belleson, Kristin, additional, Coleman, Robert L., additional, Barakat, Richard R., additional, Trimble, Edward L., additional, and Quinn, Michael, additional

Published
2016
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15. Carcinoma of the Bartholin Gland: A Review of 33 Cases

Author

Bhalwal, Asha B., primary, Nick, Alpa M., additional, dos Reis, Ricardo, additional, Chen, Chun-Ling, additional, Munsell, Mark F., additional, Ramalingam, Preetha, additional, Salcedo, Mila Pontremoli, additional, Ramirez, Pedro T., additional, Sood, Anil K., additional, and Schmeler, Kathleen M., additional

Published
2016
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18. Improved Compliance With Venous Thromboembolism Pharmacologic Prophylaxis for Patients With Gynecologic Malignancies Hospitalized for Nonsurgical Indications Did Not Reduce Venous Thromboembolism Incidence

Author

Prescott, Lauren S., primary, Kidin, Lisa M., additional, Downs, Rebecca L., additional, Cleveland, David J., additional, Wilson, Ginger L., additional, Munsell, Mark F., additional, DeJesus, Alma Y., additional, Cain, Katherine E., additional, Ramirez, Pedro T., additional, Kroll, Michael H., additional, Levenback, Charles F., additional, and Schmeler, Kathleen M., additional

Published
2015
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22. Scaling cervical cancer screening in Mozambique: analysis of loop electrosurgical excision procedure (LEEP) specimens.

Author

Chambule S, Rangeiro R, Batman S, Lathrop E, Osman N, Neves A, Mariano AAN, Nkundabatware JC, Carrilho C, Monteiro ECS, Paulo Mugolo R, Thomas JP, Carns J, Andrade V, Atif H, Baker E, Fellman BM, Richards-Kortum R, Schmeler KM, Lorenzoni C, and Salcedo MP

Subjects
Humans, Female, Mozambique, Adult, Middle Aged, Uterine Cervical Dysplasia surgery, Uterine Cervical Dysplasia pathology, Uterine Cervical Dysplasia diagnosis, Margins of Excision, Uterine Cervical Neoplasms surgery, Uterine Cervical Neoplasms pathology, Uterine Cervical Neoplasms diagnosis, Electrosurgery methods, Early Detection of Cancer methods
Abstract

Objectives: As cervical cancer screening programs are implemented and expanded, an increasing number of women require loop electrosurgical excision procedure (LEEP) for treatment of pre-invasive cervical disease. Our objective was to describe the pathological results of LEEP specimens performed as part of the MULHER study and identify factors associated with positive LEEP margins., Methods: The MULHER study enrolled 9014 women who underwent HPV testing followed by visual assessment for treatment (VAT) using visual inspection with acetic acid (VIA) and thermal ablation for those with positive results. Participants with lesions ineligible for ablation underwent LEEP. Pathology reports were reviewed for specimen size/volume, number of fragments, pathological diagnosis and margin status. Multivariable regression analysis was performed to identify variables associated with positive LEEP margins., Results: 169 participants underwent LEEP. The median age was 38 years (range 30-49). 65.1% were women living with HIV. Pathological diagnosis was available for 154 patients and included cancer (n=6, 3.9%); cervical intraepithelial neoplasia (CIN) 2/3 (n=75, 48.7%); CIN 1 (n=67, 43.5%); and normal/benign findings (n=6,3.9%). 31.8% of LEEP specimens were removed in more than one fragment. The mean specimen volume was 2.9 cm 3 (range 0.2-15.0). LEEP margin status was available for 130 patients. Positive margins (ectocervical/endocervical only, or both) were noted in 76 (58.5%) patients and associated with HIV+status (p=0.0499) and a diagnosis of CIN 2 or worse (p=0.0197). There were no associations between margin status and age, number of fragments or specimen volume., Conclusion: Our results showed a high number of LEEP specimens with positive margins. Additional evaluation is needed to better understand the characteristics of precancerous cervical lesions in this high-risk population. As cervical cancer screening programs are scaled in Mozambique and other lower-resource countries, there is a need to train providers to perform high-quality LEEP and for accurate and timely pathological interpretation., Competing Interests: Competing interests: None declared., (© IGCS and ESGO 2024. No commercial re-use. See rights and permissions. Published by BMJ.)

Published
2024
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23. The International Gynecologic Cancer Society Preinvasive Certificate Program: building a skilled workforce for the detection and treatment of cervical pre-cancer.

Author

Haney K, Ismail-Pratt I, Ng JS, Schmeler KM, and Salcedo MP

Subjects
Female, Humans, Workforce, Uterine Cervical Neoplasms diagnosis, Uterine Cervical Neoplasms therapy, Genital Neoplasms, Female diagnosis, Genital Neoplasms, Female therapy
Abstract

Competing Interests: Competing interests: None declared.

Published
2024
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24. The Mulher Study: cervical cancer screening with primary HPV testing in Mozambique.

Author

Salcedo MP, Lathrop E, Osman N, Neves A, Rangeiro R, Mariano AAN, Nkundabatware JC, Tivir G, Carrilho C, Monteiro ECS, Burny R, Thomas JP, Carns J, Andrade V, Mavume C, Paulo Mugolo R, Atif H, Hoover H, Chivambo E, Chissano M, Oliveira C, Milan J, Varon ML, Fellman BM, Baker E, Jeronimo J, Castle PE, Richards-Kortum R, Schmeler KM, and Lorenzoni C

Subjects
Female, Humans, Adult, Middle Aged, Early Detection of Cancer methods, Mozambique epidemiology, Papillomaviridae, Mass Screening methods, Uterine Cervical Neoplasms diagnosis, Uterine Cervical Neoplasms surgery, Uterine Cervical Neoplasms prevention & control, Papillomavirus Infections diagnosis, HIV Infections diagnosis, Uterine Cervical Dysplasia
Abstract

Objective: To evaluate cervical cancer screening with primary human papillomavirus (HPV) testing in Mozambique, a country with one of the highest burdens of cervical cancer globally., Methods: Women aged 30-49 years were prospectively enrolled and offered primary HPV testing using either self-collected or provider-collected specimens. Patients who tested positive for HPV underwent visual assessment for treatment using visual inspection with acetic acid to determine eligibility for thermal ablation. If ineligible, they were referred for excision with a loop electrosurgical excision procedure, for cold knife conization, or for cervical biopsy if malignancy was suspected., Results: Between January 2020 and January 2023, 9014 patients underwent cervical cancer screening. Median age was 37 years (range 30-49) and 4122 women (45.7%) were patients living with HIV. Most (n=8792, 97.5%) chose self-collection. The HPV positivity rate was 31.1% overall and 39.5% among patients living with HIV. Of the 2805 HPV-positive patients, 2588 (92.3%) returned for all steps of their diagnostic work-up and treatment, including ablation (n=2383, 92.1%), loop electrosurgical excision procedure (n=169, 6.5%), and cold knife conization (n=5, 0.2%). Thirty-one patients (1.2%) were diagnosed with cancer and referred to gynecologic oncology., Conclusion: It is feasible to perform cervical cancer screening with primary HPV testing and follow-up in low-resource settings. Participants preferred self-collection, and the majority of screen-positive patients completed all steps of their diagnostic work-up and treatment. Our findings provide important information for further implementation and scale-up of cervical cancer screening and treatment services as part of the WHO global strategy for the elimination of cervical cancer., Competing Interests: Competing interests: Cepheid loaned the study team GeneXpert machines for the project and provided the HPV testing cartridges at a reduced rate. The authors declare no competing interests., (© IGCS and ESGO 2023. No commercial re-use. See rights and permissions. Published by BMJ.)

Published
2023
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27. Telementoring in gynecologic oncology training: changing lives in Mozambique.

Author

Moretti-Marques R, Salcedo MP, Callegaro Filho D, Lopes A, Vieira M, Fontes Cintra G, Ribeiro M, Changule D, Daud S, Rangeiro R, Baker E, Lorenzoni C, Fregnani JHTG, and Schmeler KM

Subjects
Female, Genital Neoplasms, Female, Humans, Mozambique, Education, Medical, Continuing methods, Gynecology education, Mentoring methods, Surgical Oncology education, Telemedicine methods, Uterine Cervical Neoplasms surgery
Abstract

Competing Interests: Competing interests: None declared.

Published
2020
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28. Limited utility of magnetic resonance imaging in determining the primary site of disease in patients with inconclusive endometrial biopsy.

Author

Ramirez PT, Frumovitz M, Milam MR, Deavers M, dos Reis R, Iyer RB, Bhosale P, and Schmeler KM

Subjects
Adenocarcinoma diagnostic imaging, Algorithms, Biopsy, Carcinoma, Endometrioid diagnostic imaging, Carcinoma, Endometrioid pathology, Carcinoma, Endometrioid secondary, Diagnostic Techniques, Obstetrical and Gynecological, Endometrial Neoplasms secondary, Endometrial Neoplasms surgery, Female, Humans, Neoplasm Staging, Neoplasms, Unknown Primary pathology, Neoplasms, Unknown Primary surgery, Predictive Value of Tests, Radiography, Reproducibility of Results, Retrospective Studies, Adenocarcinoma pathology, Endometrial Neoplasms diagnostic imaging, Endometrial Neoplasms pathology, Magnetic Resonance Imaging methods, Neoplasms, Unknown Primary diagnostic imaging
Abstract

Objective: To evaluate the utility of preoperative magnetic resonance imaging (MRI) in determining whether primary disease site is cervical or endometrial in patients with inconclusive preoperative endometrial biopsy., Methods: We retrospectively identified all patients who underwent pelvic MRI and who had a preoperative diagnosis of cervical or endometrial cancer at MD Anderson Cancer Center between 1990 and 2006. The subset in which endometrial biopsy did not clarify the primary disease site was analyzed. Magnetic resonance imaging results were compared with postoperative histopathologic findings., Results: A total of 168 patients who underwent MRI who had a preoperative diagnosis of cervical or endometrial cancer were identified. Of these patients, 51 had an inconclusive endometrial biopsy. Magnetic resonance imaging suggested an endometrial primary tumor without cervical invasion in 28 patients, of whom 21 (75%) actually had such a tumor and 7 had an endometrial primary tumor with cervical invasion. Magnetic resonance imaging suggested an endometrial primary tumor with cervical invasion in 3 patients, all of whom had such a tumor. Magnetic resonance imaging suggested a cervical primary tumor in 6 patients, of whom 5 had such a tumor and 1 had an endometrial primary tumor without cervical invasion. Magnetic resonance imaging was inconclusive (did not clarify primary disease site or no lesion visualized) in 14 (27%) of 51 patients, 6 of whom had an endocervical primary tumor or an endometrial tumor with cervical involvement. Overall, preoperative MRI was either inaccurate or unhelpful in 22 (43%) of 51 patients., Conclusion: Preoperative MRI in patients with inconclusive endometrial biopsy is inaccurate or unhelpful in nearly half of patients.

Published
2010
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