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Your search keyword '"P. F. Fottrell"' showing total 2 results
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2 results on '"P. F. Fottrell"'

1. Intestinal lactase, sucrase and alkaline phosphatase in relation to age, sex and site of intestinal biopsy in 477 irish subjects

Author

P F Fottrell, R Keane, C F McCarthy, J G O'Grady, F M Stevens, J Sheil, B Egan-Mitchell, and B McNicholl

Subjects
Adult, Male, medicine.medical_specialty, Adolescent, Physiology, Biology, Pathology and Forensic Medicine, Lactase activity, Sucrase, Intestinal mucosa, Internal medicine, Intestine, Small, Biopsy, medicine, Humans, Intestinal Mucosa, Young adult, Child, chemistry.chemical_classification, Intestinal lactase, medicine.diagnostic_test, Age Factors, Infant, Articles, General Medicine, Middle Aged, Alkaline Phosphatase, beta-Galactosidase, Galactosidases, Endocrinology, Enzyme, chemistry, Child, Preschool, Alkaline phosphatase, Female, Sex
Abstract

Small intestinal lactase, sucrase and alkaline phosphatase activities were measured in histologically normal peroral intestinal biopsies from 477 individuals. Enzyme activities varied with age, sex, site of biopsy, and were lowest in post-weaning children and highest in young adults. Lactase activity does not decrease with advancing age.

Published
1983

2. The 15 g d-xylose absorption test: its application to the study of coeliac disease

Author

P F Fottrell, C F McCarthy, B McNicholl, F M Stevens, M A Bourke, and D. W. Watt

Subjects
Adult, medicine.medical_specialty, Time Factors, Absorption (skin), Xylose, Gastroenterology, Intestinal absorption, Coeliac disease, Pathology and Forensic Medicine, chemistry.chemical_compound, Intestinal mucosa, Internal medicine, Intestine, Small, medicine, Humans, Intestinal Mucosa, Reproducibility, business.industry, Osmolar Concentration, nutritional and metabolic diseases, General Medicine, medicine.disease, Confidence interval, digestive system diseases, Celiac Disease, Standard error, chemistry, Intestinal Absorption, business, Research Article
Abstract

The absorption of xylose following an oral load of 15 g D-xylose has been studied by serial blood levels in 17 untreated adult coeliac patients, 21 treated coeliac patients, and 30 non-coeliac patients. A statistically significant difference in xylose blood levels was found between untreated coeliac and non-coeliac patients at all the times studied, but a complete separation between these two groups occurred only at the 75 minute stage. The reproducibility of absorption was assessed by repeating the test in 16 subjects. The 95% confidence limits of the standard error of estimate are narrowest at 75 and 90 minutes.

Published
1977

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