1. Mixed-methods, descriptive and observational cohort study examining feeding and growth patterns among low birthweight infants in India, Malawi and Tanzania: the LIFE study protocol
- Author
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Jnanindra Nath Behera, Danielle E. Tuller, Lauren Spigel, Christopher Duggan, Emily Benotti, Krysten North, Stephanie L. Martin, Latha G Shamanur, Tisungane Mvalo, Sanghamitra Panda, Sujata Misra, Natalie Henrich, Rodrick Kisenge, Leena Das, Kate Miller, Kiersten Israel-Ballard, Melda Phiri, Linda S. Adair, Melissa F Young, Sarah Somji, Kimberly L Mansen, Friday Saidi, Eliza Fishman, Sunil S Vernekar, Laura Subramanian, Megan Marx Delaney, Katelyn Fleming, Linda Vesel, Nahya Salim, Anne C C Lee, Roopa M. Bellad, Karim Manji, Gowdar Guruprasad, Shivaprasad S. Goudar, Irving F. Hoffman, Christopher R. Sudfeld, Sangappa M. Dhaded, Bethany A. Caruso, and Katherine Semrau
- Subjects
Malawi ,medicine.medical_specialty ,Global Health ,Tanzania ,neonatology ,Cohort Studies ,Environmental health ,Epidemiology ,medicine ,Birth Weight ,Humans ,Neonatology ,Child ,nutrition & dietetics ,biology ,business.industry ,Public health ,Mortality rate ,public health ,Infant, Newborn ,Infant ,General Medicine ,Infant, Low Birth Weight ,biology.organism_classification ,Child development ,Observational Studies as Topic ,Medicine ,Female ,epidemiology ,business ,qualitative research ,Qualitative research ,Cohort study - Abstract
IntroductionEnding preventable deaths of newborns and children under 5 will not be possible without evidence-based strategies addressing the health and care of low birthweight (LBW, Methods and analysisLIFE is a formative, multisite, observational cohort study involving 12 study facilities in India, Malawi and Tanzania, and using a convergent parallel, mixed-methods design. We assess feeding patterns, growth indicators, morbidity, mortality, child development and health system inputs that facilitate or hinder care and survival of LBW infants.Ethics and disseminationThis study was approved by 11 ethics committees in India, Malawi, Tanzania and the USA. The results will be disseminated through peer-reviewed publications and presentations targeting the global and local research, clinical, programme implementation and policy communities.Trial registration numbersNCT04002908and CTRI/2019/02/017475.
- Published
- 2021