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Your search keyword '"Komal Agarwal"' showing total 4 results
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4 results on '"Komal Agarwal"'

2. One-year outcome of intravitreal ziv-aflibercept therapy for non-responsive neovascular age-related macular degeneration

Author

Jay Chhablani, Komal Agarwal, Ahmad M. Mansour, and Imoro Braimah

Subjects
Male, 0301 basic medicine, medicine.medical_specialty, genetic structures, Bevacizumab, Recombinant Fusion Proteins, Angiogenesis Inhibitors, 03 medical and health sciences, Cellular and Molecular Neuroscience, Imaging, Three-Dimensional, 0302 clinical medicine, Ranibizumab, Age related, medicine, Humans, Macula Lutea, Adverse effect, Aged, Retrospective Studies, Aflibercept, Aged, 80 and over, Dose-Response Relationship, Drug, business.industry, Retrospective cohort study, Drug Tolerance, Middle Aged, Macular degeneration, medicine.disease, eye diseases, Sensory Systems, Surgery, Ophthalmology, Receptors, Vascular Endothelial Growth Factor, Treatment Outcome, 030104 developmental biology, Choroidal neovascularization, Intravitreal Injections, Wet Macular Degeneration, 030221 ophthalmology & optometry, Female, sense organs, medicine.symptom, business, Tomography, Optical Coherence, Follow-Up Studies, medicine.drug
Abstract

AimTo evaluate 12-month outcome of intravitreal ziv-aflibercept (IVZ) therapy in eyes with neovascular age-related macular degeneration (nAMD) that are non-responsive to bevacizumab and ranibizumab.MethodsThis retrospective study included 16 eyes (14 patients) with nAMD who were on prior treatment with bevacizumab and ranibizumab and were treated with as-needed IVZ (1.25 mg/0.05 mL) for 12 months. The primary outcome measure was the mean change in best corrected visual acuity (BCVA) and secondary outcome measures included mean change in central macular thickness (CMT), retinal pigment epithelial detachment (RPED) heights, longest treatment free interval, presence of subretinal fluid (SRF) and intraretinal fluid (IRF) and adverse events.ResultsThere was no change in the mean logarithm of minimum angle of resolution (logMAR) BCVA at baseline and following treatment with IVZ therapy (p=0.978). The mean number of IVZ injections during 12 months was 5.9±3.3, and the mean number of antivascular endothelial growth factors (VEGFs) injections prior to switching to IVZ was 8.4±4.7. The mean treatment free interval was longer during IVZ therapy (114.4±67.1 days) compared with 76.3±54.6 days before IVZ therapy (p=0.03). Five (31.25%) eyes had visual gains of at least 0.1 logMAR, 3 (18.75%) eyes had stable BCVA (within 0.1 logMAR) and 8 (50%) eyes had BCVA decline of at least 0.1 logMAR. There was no significant difference in the mean CMT, RPED heights and presence of IRF and SRF at 12 months compared with baseline. No adverse events were noted.ConclusionIVZ increased the treatment free interval in non-responders but no significant change in visual and anatomic outcomes.

Published
2017

3. Severe anaemic retinopathy in primitive neuroectodermal tumour

Author

Abhilasha Arvind Alone and Komal Agarwal

Subjects
medicine.medical_specialty, Visual acuity, Images In…, genetic structures, Fatal Outcome, Ophthalmology, medicine, Humans, Neuroectodermal Tumors, Primitive, Peripheral, Child, Primitive neuroectodermal tumour, Retina, Spinal Neoplasms, Paraneoplastic Syndromes, Ocular, Paediatric oncology, business.industry, Anemia, General Medicine, medicine.disease, eye diseases, Left eye, medicine.anatomical_structure, Female, sense organs, medicine.symptom, business, Retinopathy
Abstract

A 9-year-old girl presented with chief complaints of sudden painless diminution of vision in both eyes 6 days ago. Her visual acuity was PL+PR accurate in the right eye and counting fingers in the left eye. She was a known case of spinal extradural primitive neuroectodermal tumour since 2016. She

Published
2019

4. Rare association of juvenile retinoschisis with retinochoroidal coloboma

Author

Komal Agarwal and Deepika C Parameswarappa

Subjects
Male, Best corrected visual acuity, medicine.medical_specialty, Retina, Images In…, genetic structures, Choroid, Retinoschisis, business.industry, General Medicine, medicine.disease, eye diseases, Coloboma, Young Adult, Left eye, medicine.anatomical_structure, Ophthalmology, medicine, Humans, Maculopathy, sense organs, Juvenile retinoschisis, Retinochoroidal coloboma, business
Abstract

A 20-year-old man presented with history of diminution of vision since 8 years. On examination his best corrected visual acuity was 20/20 in the right eye and 20/200 in the left eye. Anterior segment examination was essentially normal in both eyes. Right eye fundus showed stellate maculopathy with

Published
2019

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