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Your search keyword '"Kenter, Gemma G"' showing total 21 results
Start Over Author "Kenter, Gemma G" Publisher bmj
21 results on '"Kenter, Gemma G"'

1. Immune landscape in vulvar cancer-draining lymph nodes indicates distinct immune escape mechanisms in support of metastatic spread and growth

Author

Heeren, Anne Marijne, primary, Rotman, Jossie, additional, Samuels, Sanne, additional, Zijlmans, Henry J M A A, additional, Fons, Guus, additional, van de Vijver, Koen K, additional, Bleeker, Maaike C G, additional, Kenter, Gemma G, additional, Jordanova, Ekaterina J, additional, and de Gruijl, Tanja D, additional

Published
2021
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2. HPV-16 E6/E7 DNA tattoo vaccination using genetically optimized vaccines elicit clinical and immunological responses in patients with usual vulvar intraepithelial neoplasia (uVIN): a phase I/II clinical trial

Author

Bakker, Noor Alida Maria, primary, Rotman, Jossie, additional, van Beurden, Marc, additional, Zijlmans, Henry J MAA, additional, van Ruiten, Maartje, additional, Samuels, Sanne, additional, Nuijen, Bastiaan, additional, Beijnen, Jos, additional, De Visser, Karin, additional, Haanen, John, additional, Schumacher, Ton, additional, de Gruijl, Tanja D, additional, Jordanova, Ekaterina S, additional, Kenter, Gemma G, additional, van den Berg, Joost H, additional, and van Trommel, Nienke E, additional

Published
2021
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3. Rationale and study protocol of the Physical Activity and Dietary intervention in women with OVArian cancer (PADOVA) study: a randomised controlled trial to evaluate effectiveness of a tailored exercise and dietary intervention on body composition, physical function and fatigue in women with ovarian cancer undergoing chemotherapy

Author

Stelten, Stephanie, primary, Hoedjes, Meeke, additional, Kenter, Gemma G, additional, Kampman, Ellen, additional, Huijsmans, Rosalie J, additional, van Lonkhuijzen, Luc RCW, additional, and Buffart, LM, additional

Published
2020
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4. Role ofFAM19A4/miR124-2methylation analysis in predicting regression or non-regression of CIN2/3 lesions: a protocol of an observational longitudinal cohort study

Author

Kremer, Wieke W, primary, Berkhof, Johannes, additional, Bleeker, Maaike CG, additional, Heideman, Daniëlle AM, additional, van Trommel, Nienke E, additional, van Baal, Marchien W, additional, Verhoeve, Harold R, additional, Meijer, Chris JLM, additional, and Kenter, Gemma G, additional

Published
2019
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9. A Controlled Study on Vaginal Blood Flow During Sexual Arousal Among Early-Stage Cervical Cancer Survivors Treated With Conventional Radical or Nerve-Sparing Surgery With or Without Radiotherapy

Author

Bakker, Rinske Maria, primary, Pieterse, Quirine D., additional, van Lonkhuijzen, Luc R.C.W., additional, Trimbos, Baptist J.B.M.Z., additional, Creutzberg, Carien L., additional, Kenter, Gemma G., additional, de Kroon, Cor D., additional, and ter Kuile, Moniek M., additional

Published
2017
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10. Long-Term Morbidity and Quality of Life in Cervical Cancer Survivors: A Multicenter Comparison Between Surgery and Radiotherapy as Primary Treatment

Author

Derks, Marloes, primary, van Lonkhuijzen, Luc R.C.W., additional, Bakker, Rinske M., additional, Stiggelbout, Anne M., additional, de Kroon, Cornelis D., additional, Westerveld, Henrike, additional, Roovers, Jan Paul W.R., additional, Kenter, Gemma G., additional, and ter Kuile, Moniek M., additional

Published
2017
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13. Long-term Pelvic Floor Function and Quality of Life After Radical Surgery for Cervical Cancer: A Multicenter Comparison Between Different Techniques for Radical Hysterectomy With Pelvic Lymphadenectomy

Author

Derks, Marloes, primary, van der Velden, Jacobus, additional, Frijstein, Minke M., additional, Vermeer, Willemijn M., additional, Stiggelbout, Anne M., additional, Roovers, Jan Paul W.R., additional, de Kroon, Cornelis D., additional, ter Kuile, Moniek M., additional, and Kenter, Gemma G., additional

Published
2016
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16. Pelvic Lymphadenectomy Improves Survival in Patients With Cervical Cancer With Low-Volume Disease in the Sentinel Node: A Retrospective Multicenter Cohort Study

Author

Zaal, Afra, primary, Zweemer, Ronald P., additional, Zikán, Michal, additional, Dusek, Ladislav, additional, Querleu, Denis, additional, Lécuru, Fabrice, additional, Bats, Anne-Sophie, additional, Jach, Robert, additional, Sevcik, Libor, additional, Graf, Petar, additional, Klát, Jaroslav, additional, Dyduch, Grzegorz, additional, von Mensdorff-Pouilly, Silvia, additional, Kenter, Gemma G., additional, Verheijen, René H.M., additional, and Cibula, David, additional

Published
2014
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20. Effects of a combined exercise and dietary intervention on clinical outcomes in patients with ovarian cancer: the Physical Activity and Dietary intervention in OVArian cancer (PADOVA) randomized controlled trial.

Author

Brouwer CG, Hartman YAW, Stelten S, Kenkhuis MF, van Lonkhuijzen LRCW, Kenter GG, Kos M, van de Ven PM, Driel WJV, Winkels RM, Bekkers RLM, Ottevanger PB, Hoedjes M, and Buffart LM

Abstract

Objective: Chemotherapy treatment modifications can impact survival in patients with ovarian cancer, particularly when the relative dose intensity falls below 85%. Exercise and dietary interventions may benefit treatment tolerability. This study aimed to explore the effects of a combined exercise and dietary intervention on secondary outcomes of the Physical Activity and Dietary intervention in OVArian cancer (PADOVA) trial, specifically relative dose intensity and progression-free survival., Methods: 81 patients with ovarian cancer were randomized into a combined supervised exercise and dietary intervention during (neo)adjuvant chemotherapy or a usual care control group. Relative dose intensity was calculated as the ratio of delivered dose intensity (dose per actual time) to the standard dose for six chemotherapy cycles. The effect on relative dose intensity was analyzed using logistic regression and Bayesian posterior probability of correctly identifying the best study arm. The effect on progression-free survival was examined using Cox regression., Results: The proportion of patients achieving a relative dose intensity ≥85% was 74.4% in the intervention group compared with 61.5% in the control group (OR 2.04, 95% CI 0.75 to 5.84). The Bayesian posterior probability that the intervention group had a higher proportion of patients with a relative dose intensity ≥85% was 88.4%. Intervention effect on progression-free survival was not statistically significant (HR 1.63, 95% CI 0.82 to 3.23). At 18 months, the proportion of patients without disease progression was 73% in the intervention group and 51% in the control group., Conclusion: The proportions of patients with ovarian cancer with a relative dose intensity ≥85% and an 18-month progression-free survival were numerically higher in the intervention group compared with the control group, but these differences were not statistically significant. The higher proportions and the 88.4% probability that intervention is superior to usual care for clinical outcomes support future studies on exercise and dietary interventions with a focus on clinical outcomes as primary endpoints., Trial Registration Number: Registered in the Netherlands Trial Registry (NTR6300)., Competing Interests: Competing interests: None declared., (© IGCS and ESGO 2024. No commercial re-use. See rights and permissions. Published by BMJ.)

Published
2024
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21. The negative predictive value of clinical examination with or without anesthesia versus magnetic resonance imaging for parametrial infiltration in cervical cancer stages IB1 to IIA.

Author

Bleker SM, Bipat S, Spijkerboer AM, van der Velden J, Stoker J, and Kenter GG

Subjects
Adult, Aged, Algorithms, Carcinoma diagnostic imaging, Carcinoma pathology, Cohort Studies, Female, Humans, Middle Aged, Neoplasm Invasiveness, Neoplasm Staging, Predictive Value of Tests, Radiography, Reproducibility of Results, Retrospective Studies, Uterine Cervical Neoplasms diagnostic imaging, Uterine Cervical Neoplasms pathology, Young Adult, Anesthesia methods, Carcinoma diagnosis, Diagnostic Techniques, Obstetrical and Gynecological, Gynecological Examination methods, Magnetic Resonance Imaging methods, Pelvic Floor pathology, Uterine Cervical Neoplasms diagnosis
Abstract

Objective: This study aimed to compare the negative predictive value (NPV) of clinical examination with or without anesthesia and magnetic resonance imaging (MRI) in identifying patients with cervical carcinoma without parametrial infiltration., Methods: This retrospective cohort study was conducted at the Academic Medical Center in Amsterdam. The medical files of 203 patients diagnosed with cervical cancer stages IB1-IIA, who underwent surgical treatment between January 1, 2003, and January 31, 2011, were reviewed. We compared clinical International Federation of Gynecology and Obstetrics staging and MRI during the staging procedure. The results were compared with the parametrial status by surgical-pathological investigation, which was considered to be the reference standard., Results: Based on the surgical-pathological findings, 16.7% of the patients treated surgically had parametrial infiltration. For parametrial infiltration, examination under anesthesia (EUA) had an NPV of 65.3% and MRI of 76.9%, respectively. We found no significant difference between these NPVs., Conclusions: Examination under anesthesia and MRI are equal in identifying cervical cancer patients without parametrial infiltration with a tendency for MRI to perform better than EUA. When outpatient clinical staging is considered inconclusive, pretreatment staging may be limited to MRI. In these cases, EUA seems to have no additional value.

Published
2013
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