1. 5' nucleotidase activity in the human synovial lining in rheumatoid arthritis
- Author
-
J J Johnstone, J Chayen, and B Henderson
- Subjects
musculoskeletal diseases ,medicine.medical_specialty ,Immunology ,Arthritis ,General Biochemistry, Genetics and Molecular Biology ,5'-nucleotidase ,Arthritis, Rheumatoid ,Rheumatology ,Nucleotidases ,Internal medicine ,Nucleotidase ,medicine ,Humans ,Immunology and Allergy ,skin and connective tissue diseases ,chemistry.chemical_classification ,business.industry ,Synovial Membrane ,medicine.disease ,Molecular biology ,Kinetics ,medicine.anatomical_structure ,Enzyme ,Tissue sections ,Endocrinology ,chemistry ,Rheumatoid arthritis ,Synovial membrane ,business ,Research Article ,Densitometry ,Synovial lining - Abstract
5'-Nucleotidase (EC 3.1.3.5), a plasma membrane-bound enzyme, has been assayed in unfixed tissue sections of human synovium, activity being measured by scanning and integrating microdensitometry. Activity was markedly increased in the lining cells of the rheumatoid synovial membranes.
- Published
- 1980