1. Treatment targeted at underlying disease versus palliative care in terminally ill patients: a systematic review
- Author
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Tea Reljic, Benjamin Djulbegovic, Farina Klocksieben, and Ambuj Kumar
- Subjects
Adult ,Male ,medicine.medical_specialty ,Palliative care ,Referral ,MEDLINE ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,law ,Internal medicine ,medicine ,Humans ,Terminally Ill ,030212 general & internal medicine ,Adverse effect ,Survival analysis ,Aged ,Randomized Controlled Trials as Topic ,Aged, 80 and over ,Terminal Care ,business.industry ,Research ,Palliative Care ,Cancer ,General Medicine ,Middle Aged ,medicine.disease ,Survival Analysis ,Terminal illness ,Treatment Outcome ,030220 oncology & carcinogenesis ,Physical therapy ,Female ,End of life care ,business ,End-of-life care - Abstract
Objective To assess the efficacy of active treatment targeted at underlying disease (TTD)/potentially curative treatments versus palliative care (PC) in improving overall survival (OS) in terminally ill patients. Design We performed a systematic review and meta-analysis of randomised controlled trials (RCT). Methodological quality of included RCTs was assessed using the Cochrane risk of bias tool. Data sources Medline and Cochrane databases were searched, with no language restriction, from inception to 19 October 2016. Eligibility criteria for selecting studies Any RCT assessing the efficacy of any active TTD versus PC in adult patients with terminal illness with a prognosis of
- Published
- 2017
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