1. Clinical and pathological study of asymptomatic HBsAg carriers in Chile
- Author
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M. Gonzalez-Ceron, Ángel Cañete Ruiz, R Katz, S Donoso, M Velasco, and C de la Fuente
- Subjects
Adult ,Male ,medicine.medical_specialty ,Alcoholic liver disease ,Cirrhosis ,Adolescent ,medicine.disease_cause ,Gastroenterology ,Liver Function Tests ,Internal medicine ,Humans ,Medicine ,Chile ,Hepatitis B virus ,Hepatitis ,Hepatitis B Surface Antigens ,medicine.diagnostic_test ,business.industry ,Middle Aged ,Hepatitis B ,Prognosis ,medicine.disease ,Liver ,Liver biopsy ,Carrier State ,Immunology ,Female ,Liver function ,business ,Liver function tests ,Research Article - Abstract
A clinical, biochemical, and pathological study was performed in 38 chronic HBsAg carriers. The study group is a part of 393 carriers found among 117 705 voluntary blood donors at the National Blood Bank, Hospital del Salvador, Santiago, Chile. None of the 38 carriers had a past history of illicit drug abuse, hepatitis, or work involving a high risk of hepatitis B virus infection. Ten individuals had a normal liver biopsy, 17 reactive non-specific hepatitis, one fatty changes, four chr onic persistent hepatitis, one aggressive hepatitis, two post-necrotic cirrhosis, and three alcoholic cirrhosis. There was not a close correlation between liver function test and liver histology. The most significant laboratory finding was the postivity of alpha fetoprotein in two cases. During the follow-up the two alpha fetoprotein patients presented a hepatocarcinoma 12 and 14 months after admission to the study.
- Published
- 1978
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