1. Renal shear wave elastography and urinary procollagen type III amino-terminal propeptide (uPIIINP) in feline chronic kidney disease
- Author
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Chutimon Thanaboonnipat, Saikaew Sutayatram, Chollada Buranakarl, and Nan Choisunirachon
- Subjects
Cat ,Chronic kidney disease (CKD) ,Urinary procollagen type III amino-terminal propeptide (uPIIINP) ,Renal fibrosis ,Shear wave elastography (SWE) ,Veterinary medicine ,SF600-1100 - Abstract
Abstract Background Chronic kidney disease (CKD) is one of the most common diseases occurring in cats. It is characterized by renal fibrosis, which is strongly correlated with impairment of renal function. Since renal biopsy is not performed routinely in clinical practice, the non-invasive method of ultrasonographic shear-wave elastography (SWE) was used to determine renal parenchymal stiffness. Currently, urinary procollagen type III amino-terminal propeptide (uPIIINP) is a renal fibrosis biomarker in humans. Moreover, PIIINP is increasingly applied for identification of fibrosis in various organs in animals. Results The Young’s modulus (E) value on SWE, uPIIINP, and renal function were evaluated in 23 CKD cats and 25 healthy cats (HC). The renal cortical E values were significantly higher than those of the renal medulla in both groups (P
- Published
- 2019
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