1. Outcomes of patients with COVID-19 and coronary artery disease and heart failure: findings from the Philippine CORONA study
- Author
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Adrian I. Espiritu, John Christopher A. Pilapil, Jaime Alfonso M. Aherrera, Marie Charmaine C. Sy, Veeda Michelle M. Anlacan, Emilio Q. III Villanueva, and Roland Dominic G. Jamora
- Subjects
COVID-19 ,Coronary artery disease ,Heart failure ,Mortality ,Respiratory failure ,Intensive care unit admission ,Medicine ,Biology (General) ,QH301-705.5 ,Science (General) ,Q1-390 - Abstract
Abstract Background Patients with coronavirus disease 2019 (COVID-19) and coronary artery disease (CAD) or heart failure (HF) are more likely to have poor outcomes. This study aimed to determine the characteristics and outcomes of COVID-19 patients with CAD/HF across various institutions in the Philippines. Methods We utilized the data from the Philippine CORONA Study and compared the outcomes of admitted COVID-19 patients with CAD/HF versus those without. The Student’s t test, Mann-Whitney U test, binary logistic regression and multivariate regression analysis were utilized. Odds ratios (OR) and Kaplan-Meier curves were generated. Results We included a total of 512 patients with COVID-19 had CAD/HF and 10,369 were without. CAD/HF was significantly associated with COVID severity, all-cause mortality, death from cardiac causes, respiratory failure, and prolonged hospitalization. After adjusting for confounders, the presence of CAD/HF was still associated with death from a cardiac cause (OR 2.22, 95% CI 1.49–3.3, p
- Published
- 2024
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