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Start Over Author "Iris Pérez-Nadador" Publisher bmc
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1. Methylation analysis by targeted bisulfite sequencing in large for gestational age (LGA) newborns: the LARGAN cohort

Author

Tamara Carrizosa-Molina, Natalia Casillas-Díaz, Iris Pérez-Nadador, Claudia Vales-Villamarín, Miguel Ángel López-Martínez, Rosa Riveiro-Álvarez, Larry Wilhelm, Rita Cervera-Juanes, Carmen Garcés, Alejandro Lomniczi, and Leandro Soriano-Guillén

Subjects
Epigenome, Markers, Neonatal, Cardiovascular, Kidney, Development, Medicine, Genetics, QH426-470
Abstract

Abstract Background In 1990, David Barker proposed that prenatal nutrition is directly linked to adult cardiovascular disease. Since then, the relationship between adult cardiovascular risk, metabolic syndrome and birth weight has been widely documented. Here, we used the TruSeq Methyl Capture EPIC platform to compare the methylation patterns in cord blood from large for gestational age (LGA) vs adequate for gestational age (AGA) newborns from the LARGAN cohort. Results We found 1672 differentially methylated CpGs (DMCs) with a nominal p

Published
2023
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