1. Stromal osseous metaplasia in urothelial carcinoma of the bladder: a rare case report and literature review
- Author
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Joëlle Razafimahefa, Clément Gosset, Pierre Mongiat-Artus, Tsitohery Francine Andriamampionona, and Jérôme Verine
- Subjects
Stromal osseous metaplasia ,Metaplastic bone ,Osteoid ,Urothelial carcinoma ,Bladder ,Alkaline phosphatase ,Pathology ,RB1-214 - Abstract
Abstract Background The bone formation within bladder tumors could be encountered in 3 conditions. These might consist of malignant bone formation in mesenchymal tumors; mixed mesenchymal and epithelial tumors; and epithelial tumors with stromal osseous metaplasia (SOM). This last is relatively rare. According to the English literature, only 12 cases have been reported in primary tumor and 7 in metastatic deposits of bladder primaries. Herein, we presented an additional case. Case presentation An 83-year-old man was admitted 13 years ago for prostatic adenocarcinoma, treated with radical prostatectomy. Biochemical recurrence was detected 2 years after surgery (prostate-specific-antigen (PSA) level: 4.60 ng/mL) and progressively normalized (
- Published
- 2019
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