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Your search keyword '"Ch. Venkataramana"' showing total 2 results
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2 results on '"Ch. Venkataramana"'

1. Integration of metabolites from meta-analysis with transcriptome reveals enhanced SPHK1 in PDAC with a background of pancreatitis

Author

Vijayasarathy Ketavarapu, Vishnubhotla Ravikanth, Mitnala Sasikala, G. V. Rao, Ch. Venkataramana Devi, Prabhakar Sripadi, Murali Satyanarayana Bethu, Ramars Amanchy, H. V. V. Murthy, Stephen J. Pandol, and D. Nageshwar Reddy

Subjects
Chronic pancreatitis, Pancreatic ductal adenocarcinoma, PDAC with background of CP, SPHK1, Transcriptomics, Metabolomic biomarkers, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Background Pathophysiology of transformation of inflammatory lesions in chronic pancreatitis (CP) to pancreatic ductal adenocarcinoma (PDAC) is not clear. Methods We conducted a systematic review, meta-analysis of circulating metabolites, integrated this data with transcriptome analysis of human pancreatic tissues and validated using immunohistochemistry. Our aim was to establish biomarker signatures for early malignant transformation in patients with underlying CP and identify therapeutic targets. Results Analysis of 19 studies revealed AUC of 0.86 (95% CI 0.81-0.91, P

Published
2022
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2. Correction: Integration of metabolites from meta-analysis with transcriptome reveals enhanced SPHK1 in PDAC with a background of pancreatitis

Author

Vijayasarathy Ketavarapu, Vishnubhotla Ravikanth, Mitnala Sasikala, G. V. Rao, Ch. Venkataramana Devi, Prabhakar Sripadi, Murali Satyanarayana Bethu, Ramars Amanchy, H. V. V. Murthy, Stephen J. Pandol, and D. Nageshwar Reddy

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Published
2022
Full Text
View/download PDF

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