1. Rationale and efficacy of interleukin-1 targeting in pediatric Erdheim- Chester disease
- Author
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D. Pariente, Ulrich Meinzer, Isabelle Koné-Paut, Ta Tran, I Jéru, Jean-Claude Lecron, and Adriana Delwail
- Subjects
medicine.medical_specialty ,Pathology ,lcsh:Diseases of the musculoskeletal system ,genetic structures ,business.industry ,lcsh:RJ1-570 ,Interleukin ,lcsh:Pediatrics ,Foamy histiocytes ,Disease ,medicine.disease ,Rheumatology ,Histiocytosis ,Internal medicine ,Poster Presentation ,Pediatrics, Perinatology and Child Health ,Erdheim–Chester disease ,Medicine ,Immunology and Allergy ,Pediatrics, Perinatology, and Child Health ,lcsh:RC925-935 ,business ,Infiltration (medical) - Abstract
Erdheim-Chester disease (ECD) is a rare non-Langerhans systemic histiocytosis of unknown origin. ECD is characterized by bilateral and symmetric sclerosis of the metaphyseal regions of the long bones and infiltration in other organs. Histopathologically, ECD is characterized by a mononuclear infiltrate of foamy histiocytes.
- Published
- 2011