1. Intraparenchymal metastases as a cause for local recurrence of pancreatic cancer.
- Author
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Kiemen AL, Choi Y, Braxton AM, Almagro Pérez C, Graham S, Grahn MP, Nanda N, Roberts N, Wood L, Wu P, Hruban RH, and Wirtz D
- Subjects
- Humans, Pancreas pathology, Neoplasm Recurrence, Local pathology, Pancreatic Neoplasms, Pancreatic Neoplasms pathology
- Abstract
Using CODA, a technique for three-dimensional reconstruction of large tissues, Kiemen et al. report observation of a microscopic focus of pancreatic cancer found in the vasculature of grossly normal human pancreas tissue resected adjacent to a large tumour. They use TP53 and SMAD4 staining to relate the small focus to the primary tumour. This report describes a represents a probable case of intraparenchymal metastasis of pancreatic cancer, revealing a probable cause of local recurrence., (© 2022 John Wiley & Sons Ltd.)
- Published
- 2023
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