1. The assembly of ribosomes in HeLa cell nucleoli.
- Author
-
Lastick SM
- Subjects
- Cell Nucleolus metabolism, Cytoplasm metabolism, Electrophoresis, Polyacrylamide Gel, Humans, Kinetics, RNA, Ribosomal metabolism, HeLa Cells metabolism, Ribosomal Proteins metabolism, Ribosomes metabolism
- Abstract
The order in which ribosomal proteins become associated with nucleolar pre-rRNA was studied by measuring the kinetics of label accumulation in ribosomal proteins isolated from the cytoplasmic ribosomes, as well as by two-dimensional polyacrylamide gel electrophoresis of protein extracted from ribosome precursor particles. Tentative identifications of early-adding and late-adding groups of proteins have been made.
- Published
- 1980
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