1. Lymphadenopathy, elevated liver function tests and weight loss in a 68-year-old man.
- Author
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Krok KL, Torbenson MS, Schulick RD, and Thuluvath PJ
- Subjects
- Aged, Biopsy, Needle, Histiocytosis, Sinus complications, Humans, Immunohistochemistry, Liver Function Tests, Lymphatic Diseases diagnostic imaging, Male, Radiography, Weight Loss, Histiocytosis, Sinus diagnosis, Histiocytosis, Sinus pathology, Lymphatic Diseases etiology
- Abstract
A 68-year-old man presented to the hospital with fevers, weight loss, lymphadenopathy and abnormal liver-associated enzymes. After a thorough workup, a liver biopsy demonstrated histiocytes with phagocytosis of the lymphocytes and a positive immunostain for S-100. The diagnosis of Rosai-Dorfman disease was made. This case report will discuss the patient's presentation as well as the diagnosis and treatment of this rare, non-malignant disorder, which only rarely affects the liver.
- Published
- 2007
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