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Unlabelled: CODE 75 is a neurorehabilitation department at the General Hospital of Versilia, which specializes in serious acquired cerebral lesions., Objectives: The therapy and the maintenance of oral hygiene in patients with cerebral lesions are critical to the overall success of the rehabilitation therapy. The purpose of our project was to improve patients' quality of life, reducing the quantity of oral bacteria caused by the presence of layers of plaque on the tooth surfaces and in the oral mucosa., Methods: The dental department of Versilia Hospital conducted a 1 year follow-up study to develop specific protocols designed to obtain and improve the maintenance of these patients' oral hygiene. The oral prevention project was directed primarily at the department's medical staff and carers, and focused on improving the information available to the medical team and their direct involvement. A case report is described to show an application of the protocol. Data were recorded before the start of the protocol (T0) and after 1 month (T1)., Results: The analysis of the periodontal parameters shows a difference in values between T0 and T1. In T1 no bleeding on probing was recorded. After the causal therapy, the gingival hypertrophy and oedema disappeared as confirmed by the absence of BOP., Discussions: Results show that teamwork plays a fundamental role in this multi-professional approach for the rehabilitation of patients with acquired cerebral lesions. The success of this protocol depends on the cooperation between personnel with specific skills in the department.