1. Plasma antioxidant status (selenium, retinol and α-tocopherol) in HIV infection
- Author
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M. F. Dumon, E. Peuchant, C. Hamon, M. Simonoff, C. Conri, B. Leng, Marie-Josée Thomas, M. Clerc, C Sergeant, J. L. Pellegrin, and J. Constans
- Subjects
medicine.medical_specialty ,Antioxidant ,Chemistry ,medicine.medical_treatment ,Human immunodeficiency virus (HIV) ,Retinol ,food and beverages ,chemistry.chemical_element ,medicine.disease ,medicine.disease_cause ,Plasma selenium ,chemistry.chemical_compound ,Endocrinology ,Selenium deficiency ,Internal medicine ,medicine ,CD4 Lymphocyte ,Tocopherol ,Selenium - Abstract
Plasma antioxidant status can be evaluated by selenium, retinol and a-tocopherol. The present study concerns 89 HIV-1 positive patients. The plasma level of selenium was determined by PIXE (proton-induced X-ray emission analysis) and by measurement of levels of vitamins A and E by HPLC. The data were compared to controls; among the HIV-1 patients, significant differences were found for plasma selenium between groups selected on the basis of the CD4 lymphocyte count. Differences were also observed for plasma retinol between the HIV-1 patients and the control subjects. Correlations with other nutritional and immunological parameters were shown.
- Published
- 1994
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