Search

Your search keyword '"Pavel Kalinin"' showing total 18 results
Start Over Author "Pavel Kalinin" Publisher bioscientifica
18 results on '"Pavel Kalinin"'

7. Restoration of fertility in a woman with giant prolactinoma in response to cabergoline treatment

Author

Pavel Kalinin, Boris A. Kadashev, L I Astaf'eva, S A Agadzhanian, Galina A. Melnichenko, and Yuliya Sidneva

Subjects
medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, media_common.quotation_subject, 030209 endocrinology & metabolism, lcsh:Diseases of the endocrine glands. Clinical endocrinology, 03 medical and health sciences, 0302 clinical medicine, Cabergoline, Internal Medicine, medicine, Menstrual cycle, Prolactinoma, media_common, Pregnancy, Vacuum aspiration, lcsh:RC648-665, Obstetrics, business.industry, Hyperprolactinaemia, medicine.disease, 030220 oncology & carcinogenesis, Menarche, Gestation, business, medicine.drug
Abstract

Summary A 32-year-old woman presented with primary amenorrhoea, prolactin (PRL) level of 154 150 mIU/L and was diagnosed with a giant pituitary adenoma measuring maximum 6.2 cm. Cabergoline (CAB) treatment at a dose of 0.5 mg/week was prescribed to the patient. The treatment decreased the tumour size after 3 months (MRI scans of the brain) and brought back to normal the level of the PRL (345 mIU/L) after 6 months of CAB treatment. After 7 months of CAB treatment, menarche was achieved, and after 12 months, the patient became pregnant. She discontinued taking CAB at 4-week gestation. The pregnancy resulted in a missed miscarriage at 6–7 weeks; an abortion was conducted by the vacuum aspiration method. The MRI scans of the brain did not show any tumour enlargement. After 18 months from the start of the treatment the patient got pregnant for the second time. At 25-week gestation an MRI scan of the brain was conducted which did not show any increase in the tumour size. At 38 weeks the patient delivered a healthy full-term girl via C-section. The patient chose not to breastfeed and resumed CAB therapy after the delivery. During the treatment, the PRL level returned to the normal range and the menstrual cycle was restored. After 3 years the patient got pregnant for the third time. The patient did not receive CAB during the pregnancies; the examination did not show any tumour enlargement. Further MRI scans did not show any tumour growth. CAB therapy was effective in normalization of the PRL level, tumour shrinkage, menarche and pregnancy-induction which led to the birth of healthy children in a woman with primary amenorrhoea and a giant prolactinoma invading the skull base bones. Learning points: Giant prolactinomas are very rarely found in women. Cabergoline therapy can be effective in the normalization of the PRL level, tumour shrinkage, menarche induction in a woman with primary amenorrhoea, and giant prolactinoma. Cabergoline therapy can be effective in pregnancy induction which leads to the birth of children in a woman with giant prolactinoma. Cabergoline discontinuation did not trigger tumour enlargement during pregnancy.

Published
2019

10. The assessment of octreotide suppression test, ihc- and mr-structure, mr-signal of gh-producing pituitary adenoma for determining the prognosis of disease and management

Author

A.A. Kozhevnikov, L. V. Shishkina, Lyudmila Astafina, D L Rotin, Alexander Ambrosimov, Alena Malysheva, Vyacheslav Pronin, Alexander Vorontsov, Yury Poteshkin, Andrei Grigoriev, Tatiana Y. Demidova, Eugeny Pronin, Ivan Godkov, Elena Belysheva, Vilen Azizyan, Kristina Zherebchikova, and Pavel Kalinin

Subjects
Pathology, medicine.medical_specialty, business.industry, Pituitary adenoma, Medicine, Octreotide, Immunohistochemistry, Disease, business, medicine.disease, Signal, medicine.drug
Published
2019

12. A differentiated approach to the treatment of pituitary apoplexy

Author

Oleg Sharipov, D. V. Fomichev, Maxim Kutin, Pavel Kalinin, and Lyudmila Astafieva

Subjects
Pathology, medicine.medical_specialty, business.industry, medicine, Pituitary apoplexy, Neurology (clinical), business, medicine.disease
Published
2018

15. Combined treatment of craniopharyngiomas

Author

Yrii Trunin, Liudmila Astafyeva, Nadezhda Mazerkina, Nataliya Serova, Yuliya Sidneva, Boris A. Kadashev, Aleksander Konovalov, Dmitriy Fomichev, Maxim Kutin, and Pavel Kalinin

Subjects
medicine.medical_specialty, Combined treatment, medicine, Radiology
Published
2018

16. Cabergoline - therapy for 121 giant invasive prolactinomas

Author

Irina Klochkova, Oleg Sharipov, Liudmila Astafyeva, Boris A. Kadashev, Yuliya Sidneva, Dmitriy Fomichev, Pavel Kalinin, and Maxim Kutin

Subjects
medicine.medical_specialty, business.industry, Cabergoline, medicine, Urology, business, medicine.drug
Published
2018

18. The hyponatremia in neurosurgical patients

Author

Liudmila Astaf'eva, Maxim Kutin, Yuliya Sidneva, and Pavel Kalinin

Subjects
business.industry, Anesthesia, medicine, Hyponatremia, medicine.disease, business
Published
2017

Catalog

Books, media, physical & digital resources
See catalog results