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Herbal plants have been the primary source of medicines for humans since ancient times, and currently around eighty per cent of global population depends on traditional medical system. World Health Organization (WHO) has reported that the international market value for herbal products is approximately equivalent to $6.2 billion till the date and is believed to reach up to $5 trillion at the end of 2050. The main objective of the study is to identify the traditional uses of ashwagandha root extracts for health and longevity, keeping focus on pharmaceutical and biochemical scientific evidence to support the validity. National and international journals have been examined for concrete evidence.