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Your search keyword '"do Carmo, Rodrigo Feliciano"' showing total 13 results
Start Over Author "do Carmo, Rodrigo Feliciano" Publisher biomed central
13 results on '"do Carmo, Rodrigo Feliciano"'

8. Arbovirus exposure and subclinical myocardial dysfunction in an Indigenous population in Northeast Brazil: a cross-sectional study.

Author

Nicacio, Jandir Mendonça, de Souza, Carlos Dornels Freire, Khouri, Ricardo, Pereira, Vanessa Cardoso, do Carmo, Rodrigo Feliciano, Patriota, Pedro Vinícius Amorim de Medeiros, Nunes, Sávio Luiz Pereira, de Morais Júnior, Jeová Cordeiro, Barral-Netto, Manoel, Lima, João Augusto Costa, and Armstrong, Anderson da Costa

Subjects
GLOBAL longitudinal strain, INDIGENOUS peoples of South America, INDIGENOUS peoples, MEDICAL sciences, ZIKA virus
Abstract

Background: Human activities, such as urbanization and climate change, have facilitated the spread of arbovirus-carrying vectors, disproportionately affecting vulnerable traditional Indigenous communities. Objective: To explore the relationships between subclinical myocardial dysfunction, assessed by global longitudinal strain (GLS), and comprehensive arbovirus serology in an Indigenous population, while also describing the serological and epidemiological profile of dengue, chikungunya, and Zika viruses. Methods: This ancillary study is part of the first phase (2016–2017) of the Project of Atherosclerosis among Indigenous Populations (PAI), a cross-sectional study involving participants from two Indigenous communities with different degrees of urbanization and a highly urbanized city in Northeast Brazil. We assessed the seroprevalence of dengue, chikungunya, and Zika viruses in the Fulni-ô Indigenous community, the less urbanized and most traditional group. Additionally, we explored the relationship between these viruses and subclinical heart disease, assessed by speckle-tracking echocardiography-derived GLS. Results: One hundred seventy-four participants were included, with a median age of 45.0 years (interquartile range 38.0–55.0). The majority were female (58.6%; n = 102). The prevalence of anti-ZIKV IgG was 95.3%; anti-DENV IgG was 85.8%, and anti-CHIKV IgG was 70.9%. GLS abnormalities were detected in nearly half (48.3%) of the cohort. However, no significant association was found between arbovirus serology and GLS. Conclusions: The findings reveal a high prevalence of positive serology for arboviruses and a significant rate of subclinical cardiac dysfunction. There was no significant association between reduced left ventricular longitudinal strain and positive arbovirus serology, likely due to the limited number of participants with indications of acute contact with the viruses studied. However, the unprecedented and relevant results of this study are noteworthy, as they address critical public health issues, particularly in vulnerable populations. Further research is needed to explore these findings in more depth. [ABSTRACT FROM AUTHOR]

Published
2025
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