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Your search keyword '"Wu, Honghan"' showing total 8 results
Start Over Author "Wu, Honghan" Publisher biomed central
8 results on '"Wu, Honghan"'

6. Evaluation and improvement of the National Early Warning Score (NEWS2) for COVID-19: a multi-hospital study

Author

Carr, Ewan, Bendayan, Rebecca, Bean, Daniel, Stammers, Matt, Wang, Wenjuan, Zhang, Huayu, Searle, Thomas, Kraljevic, Zeljko, Shek, Anthony, Phan, Hang T. T., Muruet, Walter, Gupta, Rishi K., Shinton, Anthony J., Wyatt, Mike, Shi, Ting, Zhang, Xin, Pickles, Andrew, Stahl, Daniel, Zakeri, Rosita, Noursadeghi, Mahdad, O’Gallagher, Kevin, Rogers, Matt, Folarin, Amos, Karwath, Andreas, Wickstrøm, Kristin E., Köhn-Luque, Alvaro, Slater, Luke, Cardoso, Victor Roth, Bourdeaux, Christopher, Holten, Aleksander Rygh, Ball, Simon, McWilliams, Chris, Roguski, Lukasz, Borca, Florina, Batchelor, James, Amundsen, Erik Koldberg, Wu, Xiaodong, Gkoutos, Georgios V., Sun, Jiaxing, Pinto, Ashwin, Guthrie, Bruce, Breen, Cormac, Douiri, Abdel, Wu, Honghan, Curcin, Vasa, Teo, James T., Shah, Ajay M., and Dobson, Richard J. B.

Published
2021
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8. Developing automated methods for disease subtyping in UK Biobank: an exemplar study on stroke.

Author

Rannikmäe, Kristiina, Wu, Honghan, Tominey, Steven, Whiteley, William, Allen, Naomi, Sudlow, Cathie, and UK Biobank

Subjects
*HEMORRHAGIC stroke, *ISCHEMIC stroke, *NATURAL language processing, *SUBARACHNOID hemorrhage, *PRIMARY care
Abstract

Background: Better phenotyping of routinely collected coded data would be useful for research and health improvement. For example, the precision of coded data for hemorrhagic stroke (intracerebral hemorrhage [ICH] and subarachnoid hemorrhage [SAH]) may be as poor as < 50%. This work aimed to investigate the feasibility and added value of automated methods applied to clinical radiology reports to improve stroke subtyping.Methods: From a sub-population of 17,249 Scottish UK Biobank participants, we ascertained those with an incident stroke code in hospital, death record or primary care administrative data by September 2015, and ≥ 1 clinical brain scan report. We used a combination of natural language processing and clinical knowledge inference on brain scan reports to assign a stroke subtype (ischemic vs ICH vs SAH) for each participant and assessed performance by precision and recall at entity and patient levels.Results: Of 225 participants with an incident stroke code, 207 had a relevant brain scan report and were included in this study. Entity level precision and recall ranged from 78 to 100%. Automated methods showed precision and recall at patient level that were very good for ICH (both 89%), good for SAH (both 82%), but, as expected, lower for ischemic stroke (73%, and 64%, respectively), suggesting coded data remains the preferred method for identifying the latter stroke subtype.Conclusions: Our automated method applied to radiology reports provides a feasible, scalable and accurate solution to improve disease subtyping when used in conjunction with administrative coded health data. Future research should validate these findings in a different population setting. [ABSTRACT FROM AUTHOR]

Published
2021
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