11 results on '"Tani, Pekka"'
Search Results
2. Constrained spherical deconvolution-based tractography and tract-based spatial statistics show abnormal microstructural organization in Asperger syndrome
- Author
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Roine, Ulrika, Salmi, Juha, Roine, Timo, Wendt, Taina Nieminen Von, Leppämäki, Sami, Rintahaka, Pertti, Tani, Pekka, Leemans, A, Sams, Mikko, Roine, Ulrika, Salmi, Juha, Roine, Timo, Wendt, Taina Nieminen Von, Leppämäki, Sami, Rintahaka, Pertti, Tani, Pekka, Leemans, A, and Sams, Mikko
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- 2015
3. Abnormal wiring of the connectome in adults with high-functioning autism spectrum disorder
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Beeldverwerking ISI, Brain, Roine, Ulrika, Roine, Timo, Salmi, Juha, Nieminen-von Wendt, Taina, Tani, Pekka, Leppamaki, Sami, Rintahaka, Pertti, Caeyenberghs, Karen, Leemans, Alexander, Sams, Mikko, Beeldverwerking ISI, Brain, Roine, Ulrika, Roine, Timo, Salmi, Juha, Nieminen-von Wendt, Taina, Tani, Pekka, Leppamaki, Sami, Rintahaka, Pertti, Caeyenberghs, Karen, Leemans, Alexander, and Sams, Mikko
- Published
- 2015
4. Constrained spherical deconvolution-based tractography and tract-based spatial statistics show abnormal microstructural organization in Asperger syndrome
- Author
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Beeldverwerking ISI, Brain, Roine, Ulrika, Salmi, Juha, Roine, Timo, Wendt, Taina Nieminen Von, Leppämäki, Sami, Rintahaka, Pertti, Tani, Pekka, Leemans, A, Sams, Mikko, Beeldverwerking ISI, Brain, Roine, Ulrika, Salmi, Juha, Roine, Timo, Wendt, Taina Nieminen Von, Leppämäki, Sami, Rintahaka, Pertti, Tani, Pekka, Leemans, A, and Sams, Mikko
- Published
- 2015
5. Self-reported psychopathic traits among non-referred Finnish adolescents: psychometric properties of the Youth Psychopathic traits Inventory and the Antisocial Process Screening Device.
- Author
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Oshukova, Svetlana, Kaltiala-Heino, Riittakerttu, Miettunen, Jouko, Marttila, Riikka, Tani, Pekka, Aronen, Eeva T., Marttunen, Mauri, Kaivosoja, Matti, and Lindberg, Nina
- Subjects
ANTISOCIAL personality disorders ,MENTAL health of youth ,PSYCHOMETRICS ,CONFIRMATORY factor analysis ,PRINCIPAL components analysis ,DIAGNOSIS - Abstract
Background: In general psychiatric services, cost-benefit screening instruments for psychopathic traits in adolescents are needed. The aim of the present study was to study the psychometric properties of the Finnish versions of the Youth Psychopathic traits Inventory (YPI) and the Antisocial Process Screening Device (APSD-SR) in community youth. As gender-specific differences exist in psychopathic traits, we analyzed the data separately in girls and boys. Methods: The YPI and the APSD-SR were administered to 372 9th graders (174 boys and 198 girls) with a mean age of 15.06 years (SD 028). Cronbach's alphas were used to study internal consistency. The factor structures of the self-assessments were studied using both Confirmatory Factor Analysis (CFA) and Principal Component Analysis (PCA). Results: In both self-assessments, boys scored significantly higher in the total scores, Interpersonal and Affective dimension scores as well as in most sub-dimensions. In the YPI, the alpha values for total and dimensional scores ranged from 055 to 0.91 in boys and from 0.74 to 0.89 in girls and, in the APSD-SR, respectively, from 038 to 0.78 and from 0.29 to 0.78. In CFA, the three-factor model produced poor fit for both self-assessments. For the ten sub-dimensions of the YPI, the PCA suggested two factors. Extending the model into three components showed sutxiimension loadings according to the original dimensions. For the APSD-SR, the PCA regaled a five-factor structure in the male sample and a six-factor one in the female group. When limiting the model to a three factor-model, we obtained a structure, which resembled the original dimensions. Conclusions: Both the YPI and the APSD-SR are promising tools of screening for psychopathic features in Finnish community youth. The YPI turned out to be slightly better than the APSD-SR in both reliability and factor structure. However, the original three-factor models did not find support Both self-assessments were somewhat weak for tapping the callous-unemotional traits of the psychopathic character, but, again, the YPI worked better than the ASPD-SR Both self-assessments revealed significant gender differences in psychopathic character traits. [ABSTRACT FROM AUTHOR]
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- 2015
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6. Catatonic features in adolescents with schizophrenia with and without a comorbid pervasive developmental disorder.
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Waris, Petra, Lindberg, Nina, Kettunen, Kirsi, Lipsanen, Jari, and Tani, Pekka
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SCHIZOPHRENIA in adolescence ,PERVASIVE child development disorders ,CATATONIA ,AUTISM spectrum disorders ,FACIAL expression - Abstract
Background Catatonia has been associated with both schizophrenia and pervasive developmental disorders. The aim of this study was to evaluate catatonic features among adolescents suffering from schizophrenia. Further, we compared these features between adolescents with a comorbid pervasive developmental disorder and those without one. Finally, we wanted to compare the profile of catatonia-like features of our schizophrenia patients to that described earlier among persons with autism spectrum disorders. Methods The study comprised a consecutive sample of 18 adolescents with schizophrenia (mean age 15.6 years, SD 1.4) and their families. Diagnosis of schizophrenia was assessed with the Schedule for Affective Disorders and Schizophrenia for School-Aged Children - Present and Life-Time (K-SADS-PL) for the DSM-IV. The Diagnostic Interview for Social and Communication Disorders version 11 was used to assess catatonic features. Results All adolescents with schizophrenia had showed some lifetime catatonic features. Approximately 78% of them had already expressed these features before the age of 10. The number of catatonic features before the age of 10 was significantly higher among the adolescents with a comorbid pervasive developmental disorder compared to those without one. The numbers of catatonic features after the age of 10 did not significantly differ between the two groups. Over three-quarters of schizophrenia patients shared four lifetime catatonic features: "lacks facial expression", "odd intonation", "poor eye contact" and "lack of cooperation". Conclusions Adolescent schizophrenia patients with a comorbid pervasive developmental disorder show many catatonic features in childhood whereas those without one seem to develop these features first in adolescence. Catatonic features exhibited by adolescents with schizophrenia resemble those described among persons with pervasive developmental disorders without schizophrenia. [ABSTRACT FROM AUTHOR]
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- 2014
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7. Looking for pyromania: Characteristics of a consecutive sample of Finnish male criminals with histories of recidivist fire-setting between 1973 and 1993.
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Lindberg, Nina, Holi, Matti M., Tani, Pekka, and Virkkunen, Matti
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PYROMANIA ,IMPULSE control disorders ,PATHOLOGICAL psychology ,RECIDIVISTS ,CRIMINAL psychology ,FORENSIC psychiatry - Abstract
Background: As pyromania is a rare diagnosis with questionable validity, we aimed to describe a forensic psychiatric population of arson recidivists. Methods: The medical records as well as the forensic psychiatric examination statements of 90 arson recidivists referred for pretrial psychiatric assessment in Helsinki University Hospital Department of Forensic Psychiatry between 1973 and 1993 were reviewed. Results: The most important diagnostic categories of arson recidivists were personality disorders, psychosis and mental retardation, often with comorbid alcoholism. In all, 68% of arsonists were under alcohol intoxication during the index crime. Psychotic as well as mentally retarded persons with repeated fire-setting behaviour were mostly "pure arsonists"- persons guilty only of arsons during their criminal careers. Arson recidivists with personality disorder, in contrast, often exhibited various types of criminal behaviour and arson appeared to be only one expression of a wide range of criminal activity. Comorbid alcoholism was apparently a more rarely observed phenomenon among pure arsonists than in "nonpure arsonists". We found only three subjects fulfilling the present diagnostic criteria for pyromania. Conclusion: Using the criteria of the DSM-IV-TR, pyromania must be regarded as an extremely rare phenomenon. Especially the question of substance intoxication as an exclusion criterion for pyromania should be reconsidered. [ABSTRACT FROM AUTHOR]
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- 2005
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8. Increased deep sleep in a medication-free, detoxified female offender with schizophrenia, alcoholism and a history of attempted homicide: Case report.
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Lindberg, Nina, Tani, Pekka, Takala, Pirjo, Sailas, Eila, Putkonen, Hanna, Eronen, Markku, and Virkkunen, Matti
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WOMEN criminals , *SCHIZOPHRENIA , *PSYCHOLOGY of alcoholism ,SLEEP & psychology - Abstract
Background: Psychiatric sleep research has attempted to identify diagnostically sensitive and specific sleep patterns associated with particular disorders. Both schizophrenia and alcoholism are typically characterized by a severe sleep disturbance associated with decreased amounts of slow wave sleep, the physiologically significant, refreshing part of the sleep. Antisocial behaviour with severe aggression, on the contrary, has been reported to associate with increased deep sleep reflecting either specific brain pathology or a delay in the normal development of sleep patterns. The authors are not aware of previous sleep studies in patients with both schizophrenia and antisocial personality disorder. Case presentation: The aim of the present case-study was to characterize the sleep architecture of a violent, medication-free and detoxified female offender with schizophrenia, alcoholism and features of antisocial personality disorder using polysomnography. The controls consisted of three healthy, age-matched women with no history of physical violence. The offender's sleep architecture was otherwise very typical for patients with schizophrenia and/or alcoholism, but an extremely high amount of deep sleep was observed in her sleep recording. Conclusions: The finding strengthens the view that severe aggression is related to an abnormal sleep pattern with increased deep sleep. The authors were able to observe this phenomenon in an antisocially behaving, violent female offender with schizophrenia and alcohol dependence, the latter disorders previously reported to be associated with low levels of slow wave sleep. New studies are, however, needed to confirm and explain this preliminary finding. [ABSTRACT FROM AUTHOR]
- Published
- 2004
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9. Insomnia is a frequent finding in adults with Asperger syndrome.
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Tani, Pekka, Lindberg, Nina, Wendt, Taina Nieminen-von, Von Wendt, Lennart, Alanko, Lauri, Appelberg, Björn, and Porkka-Heiskanen, Tarja
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INSOMNIA , *ASPERGER'S syndrome , *AUTISM , *NEUROPSYCHOLOGICAL tests , *PSYCHOLOGY ,SLEEP & psychology - Abstract
Background: Asperger syndrome (AS) is a neurodevelopmental disorder belonging to autism spectrum disorders with prevalence rate of 0,35% in school-age children. It has been most extensively studied in childhood while there is scarcity of reports concerning adulthood of AS subjects despite the lifelong nature of this syndrome. In children with Asperger syndrome the initiation and continuity of sleep is disturbed because of the neuropsychiatric deficits inherent of AS. It is probable that sleep difficulties are present in adulthood as well. Our hypothesis was that adults with AS suffer from difficulty in initiating and maintaining sleep and nonrestorative sleep (insomnia). Methods: 20 AS without medication were compared with 10 healthy controls devoid of neuropsychiatric anamnesis. Clinical examination, blood test battery and head MRI excluded confounding somatic illnesses. Structured psychiatric interview for axis-I and axis-II disorders were given to both groups as well as Beck Depression Inventory and Wechsler adult intelligence scale, revised version. Sleep quality was assessed with sleep questionnaire, sleep diary during 6 consecutive days and description of possible sleep problems by the participants own words was requested. Results: compared with controls and with normative values of good sleep, AS adults had frequent insomnia. In sleep questionnaire 90% (18/20), in sleep diary 75% (15/20) and in free description 85% (17/20) displayed insomnia. There was a substantial psychiatric comorbidity with only 4 AS subject devoid of other axis-I or axis-II disorders besides AS. Also these persons displayed insomnia. It can be noted that the distribution of psychiatric diagnoses in AS subjects was virtually similar to that found among patient with chronic insomnia. Conclusions: the neuropsychiatric deficits inherent of AS predispose both to insomnia and to anxiety and mood disorders. Therefore a careful assessment of sleep quality should be an integral part of the treatment plan in these individuals. Conversely, when assessing adults with chronic insomnia the possibility of autism spectrum disorders as one of the potential causes of this condition should be kept in mind. [ABSTRACT FROM AUTHOR]
- Published
- 2003
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10. Abnormal wiring of the connectome in adults with high-functioning autism spectrum disorder.
- Author
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Roine U, Roine T, Salmi J, Nieminen-von Wendt T, Tani P, Leppämäki S, Rintahaka P, Caeyenberghs K, Leemans A, and Sams M
- Abstract
Background: Recent brain imaging findings suggest that there are widely distributed abnormalities affecting the brain connectivity in individuals with autism spectrum disorder (ASD). Using graph theoretical analysis, it is possible to investigate both global and local properties of brain's wiring diagram, i.e., the connectome., Methods: We acquired diffusion-weighted magnetic resonance imaging data from 14 adult males with high-functioning ASD and 19 age-, gender-, and IQ-matched controls. As with diffusion tensor imaging-based tractography, it is not possible to detect complex (e.g., crossing) fiber configurations, present in 60-90 % of white matter voxels; we performed constrained spherical deconvolution-based whole brain tractography. Unweighted and weighted structural brain networks were then reconstructed from these tractography data and analyzed with graph theoretical measures., Results: In subjects with ASD, global efficiency was significantly decreased both in the unweighted and the weighted networks, normalized characteristic path length was significantly increased in the unweighted networks, and strength was significantly decreased in the weighted networks. In the local analyses, betweenness centrality of the right caudate was significantly increased in the weighted networks, and the strength of the right superior temporal pole was significantly decreased in the unweighted networks in subjects with ASD., Conclusions: Our findings provide new insights into understanding ASD by showing that the integration of structural brain networks is decreased and that there are abnormalities in the connectivity of the right caudate and right superior temporal pole in subjects with ASD.
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- 2015
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11. Constrained spherical deconvolution-based tractography and tract-based spatial statistics show abnormal microstructural organization in Asperger syndrome.
- Author
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Roine U, Salmi J, Roine T, Wendt TN, Leppämäki S, Rintahaka P, Tani P, Leemans A, and Sams M
- Abstract
Background: The aim of this study was to investigate potential differences in neural structure in individuals with Asperger syndrome (AS), high-functioning individuals with autism spectrum disorder (ASD). The main symptoms of AS are severe impairments in social interactions and restricted or repetitive patterns of behaviors, interests or activities., Methods: Diffusion weighted magnetic resonance imaging data were acquired for 14 adult males with AS and 19 age, sex and IQ-matched controls. Voxelwise group differences in fractional anisotropy (FA) were studied with tract-based spatial statistics (TBSS). Based on the results of TBSS, a tract-level comparison was performed with constrained spherical deconvolution (CSD)-based tractography, which is able to detect complex (for example, crossing) fiber configurations. In addition, to investigate the relationship between the microstructural changes and the severity of symptoms, we looked for correlations between FA and the Autism Spectrum Quotient (AQ), Empathy Quotient and Systemizing Quotient., Results: TBSS revealed widely distributed local increases in FA bilaterally in individuals with AS, most prominent in the temporal part of the superior longitudinal fasciculus, corticospinal tract, splenium of corpus callosum, anterior thalamic radiation, inferior fronto-occipital fasciculus (IFO), posterior thalamic radiation, uncinate fasciculus and inferior longitudinal fasciculus (ILF). CSD-based tractography also showed increases in the FA in multiple tracts. However, only the difference in the left ILF was significant after a Bonferroni correction. These results were not explained by the complexity of microstructural organization, measured using the planar diffusion coefficient. In addition, we found a correlation between AQ and FA in the right IFO in the whole group., Conclusions: Our results suggest that there are local and tract-level abnormalities in white matter (WM) microstructure in our homogenous and carefully characterized group of adults with AS, most prominent in the left ILF.
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- 2015
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