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Your search keyword '"Silva, Sara"' showing total 16 results
Start Over Author "Silva, Sara" Publisher biomed central
16 results on '"Silva, Sara"'

1. Identifying biologically implausible values in big longitudinal data: an example applied to child growth data from the Brazilian food and nutrition surveillance system

Author

de Mello e Silva, Juliana Freitas, de Jesus Silva, Natanael, Carrilho, Thaís Rangel Bousquet, Jesus Pinto, Elizabete de, Rocha, Aline Santos, Pedroso, Jéssica, Silva, Sara Araújo, Spaniol, Ana Maria, da Costa Santin de Andrade, Rafaella, Bortolini, Gisele Ane, Paixão, Enny, Kac, Gilberto, de Cássia Ribeiro-Silva, Rita, and Barreto, Maurício L.

Published
2024
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5. Correction to: Assessing genotype-phenotype associations in three dorsal colour morphs in the meadow spittlebug Philaenus spumarius (L.) (Hemiptera: Aphrophoridae) using genomic and transcriptomic resources

Author

Rodrigues, Ana S. B., Silva, Sara E., Pina-Martins, Francisco, Loureiro, João, Castro, Mariana, Gharbi, Karim, Johnson, Kevin P., Dietrich, Christopher H., Borges, Paulo A. V., Quartau, José A., Jiggins, Chris D., Paulo, Octávio S., and Seabra, Sofia G.

Published
2020
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7. Infection of Anopheles aquasalis from symptomatic and asymptomatic Plasmodium vivax infections in Manaus, western Brazilian Amazon

Author

Martins-Campos, Keillen M., Kuehn, Andrea, Almeida, Anne, Duarte, Ana Paula M., Sampaio, Vanderson S., Rodriguez, Íria C., da Silva, Sara G. M., Ríos-Velásquez, Claudia María, Lima, José Bento Pereira, Pimenta, Paulo Filemon Paolucci, Bassat, Quique, Müller, Ivo, Lacerda, Marcus, Monteiro, Wuelton M., and Barbosa Guerra, Maria das Graças V.

Published
2018
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9. Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease

Author

Mishra, Neha, Aden, Konrad, Sørensen, Signe B, Overgaard, Silja H, Schulte, Berenice, Nikolaus, Susanna, Rey, Guillaume, Gasparoni, Gilles, Lyons, Paul A, Schultze, Joachim L, Walter, Jörn, Andersen, Vibeke, Blase, Johanna I, Consortium, SYSCID, Dermitzakis, Emmanouil T, Schreiber, Stefan, Rosenstiel, Philip, Banos, Aggelos, Bertsias, George, Beyer, Marc-Daniel, Boumpas, Dimitrios, Finckh, Axel, Franke, Andre, Baran, Nathan, Georges, Michel, Gu, Wei, Häsler, Robert, Jawhara, Mohamad, Kenyon, Amy, Kratsch, Christina, Krause, Roland, Lauc, Gordan, Mangino, Massimo, Natoli, Gioacchino, Bordoni, Dora, Ostaszewski, Marek, Pezer, Marija, Raes, Jeroen, Rahmouni, Souad, Ramos-Pamplona, Marilou, Reiz, Benedikt, Rosati, Elisa, Sanoudou, Despina, Satagopam, Venkata, Schneider, Reinhard, Tran, Florian, Schulte-Schrepping, Jonas, Sidiropoulos, Prodromos, Smith, Kenneth G C, Spector, Timothy, Vandeputte, Doris, Vieira-Silva, Sara, Vojta, Aleksandar, Warnat-Herresthal, Stefanie, Zoldoš, Vlatka, Conrad, Claudio, Avalos, Diana, Jaeckel, Charlot, and Scherer, Michael

Subjects
Tumor Necrosis Factor-alpha, genetics [Inflammatory Bowel Diseases], Intestinal inflammation, Therapy response, Biomarker, Biologics, Inflammatory Bowel Diseases, Personalized medicine, Infliximab, drug therapy [Inflammatory Bowel Diseases], therapeutic use [Interferons], Genetics, therapeutic use [Infliximab], Molecular Medicine, Humans, RNA, Tumor Necrosis Factor Inhibitors, ddc:610, Prospective Studies, Interferons, Molecular Biology, Genetics (clinical), Biomarkers
Abstract

Background and aims Treatment with tumor necrosis factor α (TNFα) antagonists in IBD patients suffers from primary non-response rates of up to 40%. Biomarkers for early prediction of therapy success are missing. We investigated the dynamics of gene expression and DNA methylation in blood samples of IBD patients treated with the TNF antagonist infliximab and analyzed the predictive potential regarding therapy outcome. Methods We performed a longitudinal, blood-based multi-omics study in two prospective IBD patient cohorts receiving first-time infliximab therapy (discovery: 14 patients, replication: 23 patients). Samples were collected at up to 7 time points (from baseline to 14 weeks after therapy induction). RNA-sequencing and genome-wide DNA methylation data were analyzed and correlated with clinical remission at week 14 as a primary endpoint. Results We found no consistent ex ante predictive signature across the two cohorts. Longitudinally upregulated transcripts in the non-remitter group comprised TH2- and eosinophil-related genes including ALOX15, FCER1A, and OLIG2. Network construction identified transcript modules that were coherently expressed at baseline and in non-remitting patients but were disrupted at early time points in remitting patients. These modules reflected processes such as interferon signaling, erythropoiesis, and platelet aggregation. DNA methylation analysis identified remission-specific temporal changes, which partially overlapped with transcriptomic signals. Machine learning approaches identified features from differentially expressed genes cis-linked to DNA methylation changes at week 2 as a robust predictor of therapy outcome at week 14, which was validated in a publicly available dataset of 20 infliximab-treated CD patients. Conclusions Integrative multi-omics analysis reveals early shifts of gene expression and DNA methylation as predictors for efficient response to anti-TNF treatment. Lack of such signatures might be used to identify patients with IBD unlikely to benefit from TNF antagonists at an early time point.

Published
2022

10. Assessing genotype-phenotype associations in three dorsal colour morphs in the meadow spittlebug Philaenus spumarius (L.) (Hemiptera: Aphrophoridae) using genomic and transcriptomic resources

Author

Rodrigues, Ana S. B., Silva, Sara E., Pina-Martins, Francisco, Loureiro, João, Castro, Mariana, Gharbi, Karim, Johnson, Kevin P., Dietrich, Christopher H., Borges, Paulo A. V., Quartau, José A., Jiggins, Chris D., Paulo, Octávio S., and Seabra, Sofia G.

Published
2016
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11. The cholesterol 24-hydroxylase activates autophagy and decreases mutant huntingtin build-up in a neuroblastoma culture model of Huntington's disease.

Author

Nóbrega, Clévio, Conceição, André, Costa, Rafael G., Koppenol, Rebekah, Sequeira, Raquel L., Nunes, Ricardo, Carmo-Silva, Sara, Marcelo, Adriana, Matos, Carlos A., Betuing, Sandrine, Caboche, Jocelyne, Cartier, Nathalie, and Alves, Sandro

Subjects
HUNTINGTIN protein, HUNTINGTON disease, CHOLESTEROL hydroxylase, HYDROXYCHOLESTEROLS, MUTANT proteins, CHOLESTEROL metabolism, ENZYME metabolism
Abstract

Objective: Compromised brain cholesterol turnover and altered regulation of brain cholesterol metabolism have been allied with some neurodegenerative diseases, including Huntington's disease (HD). Following our previous studies in HD, in this study we aim to investigate in vitro in a neuroblastoma cellular model of HD, the effect of CYP46A1 overexpression, an essential enzyme in cholesterol metabolism, on huntingtin aggregation and levels. Results: We found that CYP46A1 reduces the quantity and size of mutant huntingtin aggregates in cells, as well as the levels of mutant huntingtin protein. Additionally, our results suggest that the observed beneficial effects of CYP46A1 in HD cells are linked to the activation of autophagy. Taken together, our results further demonstrate that CYP46A1 is a pertinent target to counteract HD progression. [ABSTRACT FROM AUTHOR]

Published
2020
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12. Proceedings of the 3rd IPLeiria's International Health Congress: Leiria, Portugal. 6-7 May 2016

Author

Tomás, Catarina Cardoso, Oliveira, Emanuel, Sousa, D., Uba-Chupel, M., Furtado, G., Rocha, C., Teixeira, A., Ferreira, P., Alves, Celeste, Gisin, Stefan, Catarino, Elisabete, Carvalho, Nelma, Coucelo, Tiago, Bonfim, Luís, Silva, Carina, Franco, Débora, González, Jesús Alcoba, Jardim, Helena G., Silva, Rita, Baixinho, Cristina L., Presado, Mª Helena, Marques, Mª Fátima, Cardoso, Mário E., Cunha, Marina, Mendes, Joana, Xavier, Ana, Galhardo, Ana, Couto, Margarida, Frade, João G., Nunes, Carla, Mesquita, João R., Nascimento, Maria S., Gonçalves, Guilherme, Castro, Conceição, Mártires, Alice, Monteiro, Mª João, Rainho, Conceição, Caballero, Francisco P., Monago, Fatima M., Guerrero, Jose T., Monago, Rocio M., Trigo, Africa P., Gutierrez, Milagros L., Milanés, Gemma M., Reina, Mercedes G., Villanueva, Ana G., Piñero, Ana S., Aliseda, Isabel R., Ramirez, Francisco B., Ribeiro, Andrea, Quelhas, Ana, Manso, Conceição, Santos, Rafael B., Jimenez, Nuria R., Nuñez, Cristina G., Gomez, Inmaculada R., Fernandez, Mª Jose L., Marquez, Laura A., Moreno, Ana L., Huertas, Mª Jesus Tena, Seabra, Daniel, Salvador, Mª Céu, Braga, Luciene, Parreira, Pedro, Salgueiro-Oliveira, Anabela, Arreguy-Sena, Cristina, Oliveira, Bibiana F., Henriques, Mª Adriana, Santos, Joana, Lebre, Sara, Marques, Alda, Festas, Clarinda, Rodrigues, Sandra, Lumini, José, Figueiredo, Ana G., Hernandez-Martinez, Francisco J., Campi, Liliana, Quintana-Montesdeoca, Mª Pino, Jimenez-Diaz, Juan F., Rodriguez-De-Vera, Bienvenida C., Parente, Alexandra, Mata, Mª Augusta, Pereira, Ana Mª, Fernandes, Adília, Brás, Manuel, Pinto, Mª Rosário, Basto, Marta L., Rei, Ana C., Mónico, Lisete M., Sousa, Gilberta, Morna, Clementina, Freitas, Otília, Freitas, Gregório, Jardim, Ana, Vasconcelos, Rita, Horta, Lina G., Rosa, Roger S., Kranz, Luís F., Nugem, Rita C., Siqueira, Mariana S., Bordin, Ronaldo, Kniess, Rosiane, Lacerda, Josimari T., Guedes, Joana, Machado, Idalina, Almeida, Sidalina, Zilhão, Adriano, Alves, Helder, Ribeiro, Óscar, Amaral, Ana P., Santos, Ana, Monteiro, Joana, Rocha, Mª Clara, Cruz, Rui, Lourenço, Marina, Antunes, Sandra, Mendonça, Verónica, Andrade, Isabel, Osório, Nádia, Valado, Ana, Caseiro, Armando, Gabriel, António, Martins, Anabela C., Mendes, Fernando, Cabral, Lídia, Ferreira, Manuela, Gonçalves, Amadeu, Luz, Tatiana D., Luz, Leonardo, Martins, Raul, Morgado, Alice, Vale-Dias, Maria L., Porta-Nova, Rui, Fleig, Tânia C., Reuter, Éboni M., Froemming, Miriam B., Guerreiro, Sabrina L., Carvalho, Lisiane L., Guedelha, Daniel, Coelho, P., Pereira, A., Calha, António, Cordeiro, Raul, Gonçalves, Ana, Certo, Ana, Galvão, Ana, Welter, Aline, Pereira, Elayne, Ribeiro, Sandra, Kretzer, Marcia, Jiménez-Díaz, Juan-Fernando, Jiménez-Rodríguez, Carla, Hernández-Martínez, Francisco-José, Rodríguez-De-Vera, Bienvenida-Del-Carmen, Marques-Rodrigues, Alexandre, Coelho, Patrícia, Bernardes, Tiago, Pereira, Alexandre, Sousa, Patrícia, Filho, João G., Nazario, Nazare, Amaral, Odete, Garrido, António, Veiga, Nélio, Pedro, Ana R., Pereira, Carlos, Almeia, António, Fernandes, Helder M., Vasconcelos, Carlos, Sousa, Nelson, Reis, Victor M., Monteiro, M. João, Mendes, Romeu, Pinto, Isabel C., Pires, Tânia, Gama, João, Preto, Vera, Silva, Norberto, Magalhães, Carlos, Martins, Matilde, Duarte, Mafalda, Paúl, Constança, Martín, Ignácio, Pinheiro, Arminda A., Xavier, Sandra, Azevedo, Julieta, Bento, Elisabete, Marques, Cristiana, Marques, Mariana, Macedo, António, Pereira, Ana T., Almeida, José P., Almeida, António, Alves, Josiane, Saavedra, Francisco, Maia, Ana S., Oliveira, Michelle T., Sousa, Anderson R., Ferreira, Paulo P., Lopes, Luci S., Santiago, Eujcely C., Monteiro, Sílvia, Jesus, Ângelo, Colaço, Armanda, Carvalho, António, Silva, Rita P., Cruz, Agostinho, Ferreira, Ana, Marques, Catarina, Figueiredo, João P., Paixão, Susana, Lopes, Carla, Moreira, Fernando, Ribeiro, Diana, Fernandes, Telma, Amado, Diogo, Leal, Jéssica, Azevedo, Marcelo, Ramalho, Sónia, Mangas, Catarina, Ribeiro, Jaime, Gonçalves, Rita, Nunes, Amélia F, Tuna, Ana R., Martins, Carlos R., Forte, Henriqueta D., Costa, Cláudia, Tenedório, José A., Santana, Paula, Andrade, J.A., Pinto, J.L., Campofiorito, C., Nunes, S., Carmo, A., Kaliniczenco, A., Alves, B., Mendes, F., Jesus, C., Fonseca, F., Gehrke, F., Albuquerque, Carlos, Batista, Rita, Cunha, Madalena, Madureira, António, Ribeiro, Olivério, Martins, Rosa, Madeira, Teresa, Peixoto-Plácido, Catarina, Santos, Nuno, Santos, Osvaldo, Bergland, Astrid, Bye, Asta, Alarcão, Violeta, Goulão, Beatriz, Mendonça, Nuno, Nicola, Paulo, Clara, João G., Gomes, João, Querido, Ana, Tomás, Catarina, Carvalho, Daniel, Cordeiro, Marina, Rosa, Marlene C., Brandão, Daniela, Araújo, Lia, Minghelli, Beatriz, Richaud, Sylvina, Mendes, Ana L., Marta-Simões, Joana, Trindade, Inês A., Ferreira, Cláudia, Carvalho, Teresa, Pinto-Gouveia, José, Fernandes, Morgana C., Medeiros, Anabela, Pimentel, Rafaela, Fernandes, Andreia, Mendonça, Carlos, Andrade, Susana, Menezes, Ruth L., Bravo, Rafael, Miranda, Marta, Ugartemendia, Lierni, Tena, José Mª, Pérez-Caballero, Francisco L., Fuentes-Broto, Lorena, Rodríguez, Ana B., Carmen, Barriga, Carneiro, M.A., Domingues, J.N., Paixão, S., Figueiredo, J., Nascimento, V.B., Mendes, F, Azzalis, L., Martins, Ana R., Nunes, Amélia, Jorge, Arminda, Amorim, Ana, Silva, André, Martinho, Liliana, Monteiro, Luís, Silva, Rafael, Coelho, Carina, Coelho, Inês, Correia, André, Rodrigues, Diana, Marante, Nídia, Silva, Pedro, Carvalho, Sara, Araujo, André Rts, Ribeiro, Maximiano, Coutinho, Paula, Ventura, Sandra, Roque, Fátima, Calvo, Cristina, Reses, Manoela, Conde, Jorge, Figueiredo, João, Silva, David, Seiça, Luís, Soares, Raquel, Mourão, Ricardo, Kraus, Teresa, Abreu, Ana C., Padilha, José M., Alves, Júlia M., Sousa, Paulino, Oliveira, Manuel, Sousa, Joana, Novais, Sónia, Mendes, Felismina, Pinto, Joana, Cruz, Joana, Duarte, Hugo, Dixe, Maria Dos Anjos, Sousa, Pedro, Cruz, Inês, Bastos, Fernanda, Pereira, Filipe, Carvalho, Francisco L., Oliveira, Teresa T., Raposo, Vítor R., Ribeiro, José C., Barroso, Isabel, Rodrigues, Vítor, Neves, Carmo, Oliveira, Teresa C., Oliveira, Bárbara, Morais, Mª Carminda, Baylina, Pilar, Rodrigues, Rogério, Azeredo, Zaida, Vicente, Corália, Dias, Hélia, Sim-Sim, Margarida, Castilho, Amélia, Melo, Rosa, Graveto, João, Gomes, José, Vaquinhas, Marina, Carvalho, Carla, Mónico, Lisete, Brito, Nuno, Sarroeira, Cassilda, Amendoeira, José, Cunha, Fátima, Cândido, Anabela, Fernandes, Patrícia, Silva, Helena R., Silva, Elsa, Lapa, Leila, Antunes, Cristina, Gomes, Mª José, Escanciano, Susana R., Freitas, Maria, Marôco, João, Fernandes, Ana R., Cabral, Cremilde, Alves, Samuel, Ferreira, António, Príncipe, Fernanda, Seppänen, Ulla-Maija, Ferreira, Margarida, Carvalhais, Maribel, Silva, Marilene, Silva, Joana, Neves, Jéssica, Costa, Diana, Santos, Bruno, Duarte, Soraia, Marques, Sílvia, Mendes, Isabel, Louro, Clarisse, Menino, Eva, Dixe, Maria, Dias, Sara S., Valim, Frederico C., Costa, Joyce O., Bernardes, Lúcia G., Prebianchi, Helena, Rosa, Marlene Cristina, Gonçalves, Narcisa, Martins, Maria M., Kurcgant, Paulina, Vieira, André, Bento, Sandrina, Deodato, Sérgio, Rabiais, Isabel, Reis, Laura, Torres, Ana, Soares, Sérgio, Graça, Pedro, Leitão, Céu, Abreu, Renato, Bellém, Fernando, Almeida, Ana, Ribeiro-Varandas, Edna, Tavares, Ana, Henriques, Carolina, Jordão, Célia, Neco, Sofia, Morais, Carminda, Ferreira, Pedro, Silva, Carla R., Brito, Alice, Silva, Antónia, Postolache, Gabriela, Oliveira, Raul, Moreira, Isabel, Pedro, Luísa, Vicente, Sónia, Domingos, Samuel, Postolache, Octavian, Silva, Darlen, Schneider, Dulcineia, Marques, Fátima M., Pinto, Carlos, Vicente, Sara, Breda, São João, Gomes, José H., Salgueiro, Anabela, Duarte, Nuno, Lopes, José C., Nunes, Hélder, Braga, Luciene M., Araújo, Beatriz, Alves, José M., Sousa, Ana S., Ferrito, Cândida, Ferreira, Pedro L., Rodrigues, Alexandre, Oliveira, Isabel, Martins, Cristina, Macedo, Ana P., Araújo, Odete, Augusto, Cláudia, Braga, Fátima, Gomes, Lisa, Silva, Maria A., Rosário, Rafaela, Pimenta, Luís, Carreira, Diana, Teles, Patrícia, Barros, Teresa, Jácome, Cristina, Capelas, Sylvie, Hall, Andreia, Alves, Dina, Lousada, Marisa, Loureiro, Mª Helena, Camarneiro, Ana, Silva, Margarida, Mendes, Aida, Pedreiro, Ana, G. Silva, Anne, Coelho, Elza S., Melo, Flávio, Ribeiro, Fernando, Torres, Rui, Costa, Rui, Pinho, Tânia, Cruz, Bárbara, Carreiras, Diogo, Ventura, Maria, Cruz, x, Brooks, Dina, Pinto, M Rosário, Lima-Basto, Marta, Neves, Miguel, Bizarro, Carla, Margarida, Couto, Amorim, Ana P., Silva, Eduardo, Cruz, Susana, Valente, Jorge, Guerrero, José T., Gonzalez, Estefania P., Monago, Fátima M., Ugalde, Lierni U., Vélez, Marta M., Tena, Maria J., Becerra, Isabel A., Agudelo, Mª Elizabeth, Acedo, Guadalupe, Bajo, Roberto, Malheiro, Isabel, Gaspar, Filomena, Barros, Luísa, Furtado, Guilherme, Uba-Chupel, Mateus, Rama, Luís, Braga, Margarida, Ferreira, José P., Teixeira, Ana Mª, Cruz, João, Barbosa, Tiago, Simões, Ângela, Coelho, Luís, Martinez-Hernandez, Francisco, Rodriguez-De-Vera, Bienvenida, Rodrigues, Alexandrina, Ramalho, André, Petrica, João, Mendes, Pedro, Serrano, João, Santo, Inês, Rosado, António, Mendonça, Paula, Freitas, Kátia, Ferreira, Dora, Brito, António, Fernandes, Renato, Gomes, Sofia, Pinho, Cláudia, Oliveira, Rita, Oliveira, Ana I., Casimiro, Ana P., Martins, Patrícia, Silva, Iryna, Evangelista, Diana, Leitão, Catarina, Velosa, Fábia, Carecho, Nélio, Dixe, Anjos, Catarino, Helena, Soares, Fátima, Gama, Ester, Gordo, Clementina, Moreira, Eliana, Midões, Cristiana, Santos, Marlene, Machado, Sara, Oliveira, Vânia P., Marques, Rita, Charepe, Zaida, Antunes, Ana, Santos, Sofia, Marques, Silvana F., CaroMinghelli, Eulália, Luís, Mª José, Brandão, Teresa, Marinho, Daniel, Monteiro, Diogo, Paulo, Rui, Monteiro, Lina, Ramalho, Fátima, Santos-Rocha, Rita, Morgado, Sónia, Bento, Teresa, Silva, Isabel, Azevedo, Tatiana, Soares, Salete, Pisco, Jacinta, Olszewer, Efrain O., Oliveira, Sebastião T., Santos, Erica, Maia, Carla, Mendes, Maria F., Oliveira, Rita F., Barreira, Eduarda, Pereira, Ana, Vaz, Josiana A., Novo, André, Silva, Luís D., Maia, Bruno, Ferreira, Eduardo, Pires, Filipa, Andrade, Renato, Camarinha, Luís, César, Ana F., Poço, Mariana, Ventura, David, Loura, Raquel, Gomes, Pedro, Gomes, Catarina, Silva, Cláudia, Melo, Elsa, Lindo, João, Domingos, Joana, Mendes, Zaida, Poeta, Susana, Carvalho, Tiago, Dixe, Mª Anjos, Garcia, Inês, Meneses, Rui, Afonso, Carlos, Faria, Luís, Seixas, Adérito, Granjo, Paulo, Gomes, José C., Souza, Nelba R., Furtado, Guilherme E., Rocha, Saulo V., Silva, Paula, Carvalho, Joana, Morais, Marina Ana, Lebre, Paula, Alencar, Liana, Cardoso, Ilda, Daniel, Fernanda, Luz, Tatiana, Ramos, Maurício R., Medeiros, Dayse C., Carmo, Bruno M., Seabra, André, Padez, Cristina, Silva, Manuel C., Rodrigues, António, Coelho, Alexandre, Caminha, Madson, Matheus, Filipe, Mendes, Elenice, Correia, Jony, Rodriguez-De-Vera, Bienvendida C., Jimenez-Rodriguez, Carla, Armas-Gonzalez, Yadira, Rodrigues, Cátia, Pedroso, Rosa, Apolinário-Hagen, Jennifer, Vehreschild, Viktor, Veloso, Milene, Magalhães, Celina, Cabral, Isabel, Ferraz, Maira, Nave, Filipe, Costa, Emília, Matos, Filomena, Pacheco, José, Dias, António, Duarte, João, Silva, Daniel, Alferes, Valentim R., Brêda, Mª São João, Parreira, Pedro M., Pimenta, Rui, Boavida, José, Silva, Catarina, Ribeiro, Maria, Viega-Branco, Maria, Pereira, Filomena, Almeida, Fabrícia M., Estevez, Gustavo L., Kretzer, Marcia R., João, Paulo V., Nogueira, Paulo, Novais, Sandra, Carneiro, Lara, Mota, Maria, Santiago, Luiz, Fontes-Ribeiro, Carlos, Coutinho, André P., Neto, João S., Vasconcelos, Lélia R., Dantas, Estélio, Dinis, Alexandra, Carvalho, Sérgio, Castilho, Paula, Sarreira-Santos, Alexandra, Figueiredo, Amélia, Medeiros-Garcia, Lurdes, Seabra, Paulo, Rodrigues, Rosa, Fernandes, Paula O., Santiago, Conceição, Figueiredo, Mª Henriqueta, Guimarães, Teresa, Coelho, André, Graça, Anabela, Silva, Ana M., Fonseca, Ana R., Vale-Dias, Luz, Minas, Bárbara, Franco-Borges, Graciete, Simões, Cristina, Serra, Ana, Matos, Maria, Jesus, Luís, Tavares, Ana S., Varandas, Edna, Miranda, Cristiana, Guimarães, Pedro, Gonçalves, Rodrigo, San-Martin, Elisabete A., Goulart, Cássia L., Schneiders, Paloma B., Miranda, Natacha F., Silva, Andrea G., Topa, Joana, Nogueira, Conceição, Neves, Sofia, Ventura, Rita, Nazaré, Cristina, Freitas, Alberto, Mercê, Cristiana, Branco, Marco, Almeida, Pedro, Nascimento, Daniela, Pereira, Juliana, Catela, David, Rafael, Helga, Reis, Alcinda C., Mendes, Ana, Valente, Ana R., Sousa, Diana, Baltazar, Ana L., Oliveira, Ana, Aparício, José, Neves, Joana, Ayoub, Rodrigo, Sousa, Luís, Marques-Vieira, Cristina, Severino, Sandy, José, Helena, Cadorio, Inês, Andrade, Diogo, Domingues, Cátia, Schukg, Susann, Abrantes, Ana M., Gonçalves, Ana C., Sales, Tiago, Teixo, Ricardo, Estrela, Jéssica, Laranjo, Mafalda, Casalta-Lopes, João, Rocha, Clara, Simões, Paulo C., Sarmento-Ribeiro, Ana B., Botelho, Mª Filomena, Rosa, Manuel S., Fonseca, Virgínia, Colaço, Diogo, Neves, Vanessa, Jesus, Carlos, Hesse, Camilla, Svensson, Lola, Siba, Wafa A., Pereira, Cristina, Tomaz, Jorge, Duarte, Diana, Lopes, Nuno V., Fonseca-Pinto, Rui, Brandão, Piedade, Martins, Laura, Cardoso, Margarida, Morais, Nuno, Alves, Nuno, Faria, Paula, Mateus, Artur, Morouço, Pedro, Ferreira, Nelson, Cardoso, Andreia, Lopes, Albino, Soares, Valter, Dias, Tiago, Vardasca, Ricardo, Gabriel, Joaquim, Paredes, Hugo, Reis, Arsénio, Marinho, Sara, Filipe, Vítor, Lains, Jorge, Barroso, João, Da Motta, Carolina, Carvalho, Célia B., Peixoto, Ermelindo, Gomes, Ana A., Costa, Vanessa, Couto, Diana, Marques, Daniel R., Leitão, José A., Tavares, José, Azevedo, Maria H., Silva, Carlos F., Freitas, João, Garcia-Gordillo, Miguel A., Collado-Mateo, Daniel, Chen, Gang, Iezzi, Angelo, Sala, José A., Parraça, José A., Gusi, Narcis, Sousa, Jani, Jardim, Jacinto, Pereira, Anabela, Simões, Sónia, Sardo, Pedro, Guedes, Jenifer, Machado, Paulo, Benevides, Joana, Sousa, Marina, Cabral, Joana, Carvalho, Rosa, Alves, Juliana, Azevedo, Mª Helena, Silva, Carlos, Lee, Huei D., Spolaôr, Newton, Oliva, Jefferson T., Chung, Wu F., Bairros, Keila, Silva, Cláudia D., Souza, Clóvis A., Schroeder, Silvana S., Araújo, Elsa, Monteiro, Helena, Costa, Ricardo, Torgal, Jorge, Henriques, Carolina G., Santos, Luísa, Caceiro, Elisa F., Ramalho, Sónia A., Afreixo, Vera, Santos, João, Mota, Priscilla, Pimentel, Francisco, Caldeira, Suzana N., Ribeiro, Lígia C., Aquino, Priscila S., Ribeiro, Samila G., Pinheiro, Ana B., Lessa, Paula A., Oliveira, Mirna F., Brito, Luísa S., Pinto, Ítalo N., Furtado, Alessandra S., Castro, Régia B., Aquino, Caroline Q., Martins, Eveliny S., Pinheiro, Ana B, Oliveira, Lara L., Pinheiro, Patrícia C., Sousa, Caroline R., Freitas, Vívien A., Silva, Tatiane M., Lima, Adman S., Andrade, Karizia V., Oliveira, Camila A., Vidal, Eglidia F., Ganho-Ávila, Ana, Moura-Ramos, Mariana, Gonçalves, Óscar, Almeida, Jorge, Silva, Armando, Brito, Irma, Amado, João, Rodrigo, António, Gomes, Fernando, Luís, Sara, Cavalheiro, Luís, Gonçalves, Rui, Lopes, Rui S., Fiorin, Bruno H., Santos, Marina S., Oliveira, Edmar S., Moreira, Rita L., Oliveira, Elizabete A., Filho, Braulio L., Palmeira, Lara, Garcia, Teresa, Cardoso, Sara, Oliveira, Sara, Campos, Mariana, Gaudêncio, Iris, Martins, Fernando, Ferreira, Lino, Lopes, Nuno, Marques, Ana R., Carvalho, Rui, Costa, Pablo O., Silva, Maiza M., Alvarenga-Martins, Nathália, Pinto, Paulo F., Oliveira, Denize C., Parreira, Pedro D., Gomes, Antônio T., Lage, Isabel, Cabrita, José, Teixeira, Laetitia, Silva, Sara, Cordeiro, Eugénio, Pimentel, João, Ferro-Lebres, Vera, Souza, Juliana A., Tavares, Mariline, Passadouro, Rui, Peralta, Teresa, Ferreira, Carlos, Lourenço, Georgina, Honório, Samuel, Simões, Alexandra, Carvalho, Lucinda, Figueiredo, Daniela, Valente, Carolina, Ribas, Patrícia, Brandão, Frederico, Sousa, Cesar, Mendes, Francisco, Fernandes, Rosina, Martins, Emília, Magalhães, Cátia, Araújo, Patrícia, Grande, Carla, Vieitez, Juan G., Bianchini, Bruna, Costa, Tânia, Almeida, Armando, Baffour, Gabriel, Laranjeira, Carlos, Guerra, Magda, Barbeiro, Ana P., Ferreira, Regina, Lopes, Sara, Nunes, Liliana, Martins, Julian, Magajewski, Flávio, Soares, Célia, Marques, António, Batista, Marco, Castuera, Ruth J., Mesquita, Helena, Faustino, António, Santos, Jorge, Vizzotto, Betina P., Frigo, Leticia, Pivetta, Hedioneia F., Sardo, Dolores, Abreu, Wilson, Figueiredo, Mª Céu, Jimenez-Castuera, Ruth, Silveira, Paulo, Oliveira, Catarina, Rodriguez, Cláudia K., Kretzer, Márcia R., Nazário, Nazaré O., Cruz, Pedro, Vaz, Daniela C., Ruben, Rui B., Avelelas, Francisco, Silva, Susana, Campos, Mª Jorge, Almeida, Maria, Gonçalves, Liliana, Antunes, Lígia, Simões, João, Cardoso, Susana, Loureiro, Isabel, Santos, Flávia, Alves, Gilberto, Soar, Cláudia, Marsi, Teresa O., Silva, Ernestina, Pedrosa, Dora, Leça, Andrea, Gomes, Maria, Fernandes, Paula, Noné, Ana, Combadão, Jaime, Ramalhete, Cátia, Figueiredo, Paulo, Caeiro, Patrícia, Fontana, Karine C., Machado, Patrícia O., Borges, Raphaelle, Barbosa, Flávio, Sá, Dayse, Brunhoso, Germana, Aparício, Graça, Carvalho, Amâncio, Garcia, Ana P., Santos, Adriana, Brás, Carina, Carvalho, Inês, Batalha, Joana, Glória, Margarida, Bexiga, Filipa, Paraíso, Nilson, Lima, Cristóvão F., Dias, Alberto P., Espada, Mário, Marques, Mário, Veiga-Branco, Mª, Lima, Vera, Cruz, Graça, Barreiros, Luísa, Duarte, Catarina, Lima, Teresa Maneca, Medina, María S., Blanco, Valeriana G., Lopes, Elisa, Virgolino, Ana, Ambrósio, Sara, Almeida, Inês, Marques, Tatiana, Heitor, Mª João, Olivares, Pedro R., Oliveira, Anabela, Cheio, Mónica, Pereira, Olívia R., Pinto, Sara, Oliveira, Adriana, Manso, M. Conceição, Sousa, Carla, Vinha, Ana F., Machado, Mª Manuela, Vieira, Margarida, Fernandes, Beatriz, Tomás, Teresa, Quirino, Diogo, Desouzart, Gustavo, Matos, Rui, Bordini, Magali, Mouroço, Pedro, Matos, Ana R., Serapioni, Mauro, Costa, André, Ribeiro, João, Lobato, João, Martin, Inmaculada Z., Björklund, Anita, Tavares, Aida I., Tavares, Nuno, Valente, João, Ortiga, Angela B., Calvo, Mª Cristina, Natal, Sônia, Pereira, Marta, Prata, Ana R., Nelas, Paula, Carneiro, Juliana, Couto, Cristina, Souza, Géssica M., Almada, Lívia F., Conceição, Milena A., Domingues, Gabriela, Ferreira, Irina, Costa, Ana R., Cardoso, Américo, Meireles, Alexandra, Vieira, Viviane L., Vincha, Kellem R., Cervato-Mancuso, Ana Mª, Faria, Melissa, Reis, Cláudia, Cova, Marco P., Ascenso, Rita T., Almeida, Henrique A., Oliveira, Eunice G., Santana, Miguel, Pereira, Rafael, Jesus, Rita, Tapadas, Rodrigo, Tim-Tim, Carolina, Cezanne, Catarina, Lagoa, Matilde, Lopes, João, Almeida, Henrique, Amado, Sandra, Carrão, Luís, Saboga-Nunes, Luís, Oliveira, Suzete, Escoval, Ana, Assunção, Victor, Luís, Henrique, Luís, Luís, Fotschl, Ulrike, Lirk, Gerald, Silva, Paula A., Ruivo, Joana, Silva, Vânia, Ferraz, Vera, Neves, Joel, Correia, Telma, Amorim, Helena, Pereira, Elsa S., Santos, Leonino S., Reis, Ana S., Rombo, João, Fernandes, Jorge C., Freire, Ana, Francisco, Irene, Louro, Mª Clarisse, Lopes, Saudade, Oliveira, Ana P., Gordo, Sara, Queirós, Paulo, Rodrigues, Teresa, Lobão, Catarina, Moura, Cynthia B., Dreyer, Laysa C., Meneghetti, Vanize, Cabral, Priscila P., Pinto, Francisca, Esteves, Mª Raquel, Galvão, Sofia, Tytgat, Ite, Casas-Novas, Mónica, Bernardo, Helena, Sousa, Gracinda, Sousa, Ana P., Belo, Pedro, Martins, Fátima, Pulido-Fuentes, Montserrat, Cabral, Gil, Prado, Alessandro, Carvalho, Yara M., Campos, Maria, Moreira, Liliana, Ferreira, José, Teixeira, Ana, Tomás, Catarina Cardoso, Oliveira, Emanuel, Sousa, D., Uba-Chupel, M., Furtado, G., Rocha, C., Teixeira, A., Ferreira, P., Alves, Celeste, Gisin, Stefan, Catarino, Elisabete, Carvalho, Nelma, Coucelo, Tiago, Bonfim, Luís, Silva, Carina, Franco, Débora, González, Jesús Alcoba, Jardim, Helena G., Silva, Rita, Baixinho, Cristina L., Presado, Mª Helena, Marques, Mª Fátima, Cardoso, Mário E., Cunha, Marina, Mendes, Joana, Xavier, Ana, Galhardo, Ana, Couto, Margarida, Frade, João G., Nunes, Carla, Mesquita, João R., Nascimento, Maria S., Gonçalves, Guilherme, Castro, Conceição, Mártires, Alice, Monteiro, Mª João, Rainho, Conceição, Caballero, Francisco P., Monago, Fatima M., Guerrero, Jose T., Monago, Rocio M., Trigo, Africa P., Gutierrez, Milagros L., Milanés, Gemma M., Reina, Mercedes G., Villanueva, Ana G., Piñero, Ana S., Aliseda, Isabel R., Ramirez, Francisco B., Ribeiro, Andrea, Quelhas, Ana, Manso, Conceição, Santos, Rafael B., Jimenez, Nuria R., Nuñez, Cristina G., Gomez, Inmaculada R., Fernandez, Mª Jose L., Marquez, Laura A., Moreno, Ana L., Huertas, Mª Jesus Tena, Seabra, Daniel, Salvador, Mª Céu, Braga, Luciene, Parreira, Pedro, Salgueiro-Oliveira, Anabela, Arreguy-Sena, Cristina, Oliveira, Bibiana F., Henriques, Mª Adriana, Santos, Joana, Lebre, Sara, Marques, Alda, Festas, Clarinda, Rodrigues, Sandra, Lumini, José, Figueiredo, Ana G., Hernandez-Martinez, Francisco J., Campi, Liliana, Quintana-Montesdeoca, Mª Pino, Jimenez-Diaz, Juan F., Rodriguez-De-Vera, Bienvenida C., Parente, Alexandra, Mata, Mª Augusta, Pereira, Ana Mª, Fernandes, Adília, Brás, Manuel, Pinto, Mª Rosário, Basto, Marta L., Rei, Ana C., Mónico, Lisete M., Sousa, Gilberta, Morna, Clementina, Freitas, Otília, Freitas, Gregório, Jardim, Ana, Vasconcelos, Rita, Horta, Lina G., Rosa, Roger S., Kranz, Luís F., Nugem, Rita C., Siqueira, Mariana S., Bordin, Ronaldo, Kniess, Rosiane, Lacerda, Josimari T., Guedes, Joana, Machado, Idalina, Almeida, Sidalina, Zilhão, Adriano, Alves, Helder, Ribeiro, Óscar, Amaral, Ana P., Santos, Ana, Monteiro, Joana, Rocha, Mª Clara, Cruz, Rui, Lourenço, Marina, Antunes, Sandra, Mendonça, Verónica, Andrade, Isabel, Osório, Nádia, Valado, Ana, Caseiro, Armando, Gabriel, António, Martins, Anabela C., Mendes, Fernando, Cabral, Lídia, Ferreira, Manuela, Gonçalves, Amadeu, Luz, Tatiana D., Luz, Leonardo, Martins, Raul, Morgado, Alice, Vale-Dias, Maria L., Porta-Nova, Rui, Fleig, Tânia C., Reuter, Éboni M., Froemming, Miriam B., Guerreiro, Sabrina L., Carvalho, Lisiane L., Guedelha, Daniel, Coelho, P., Pereira, A., Calha, António, Cordeiro, Raul, Gonçalves, Ana, Certo, Ana, Galvão, Ana, Welter, Aline, Pereira, Elayne, Ribeiro, Sandra, Kretzer, Marcia, Jiménez-Díaz, Juan-Fernando, Jiménez-Rodríguez, Carla, Hernández-Martínez, Francisco-José, Rodríguez-De-Vera, Bienvenida-Del-Carmen, Marques-Rodrigues, Alexandre, Coelho, Patrícia, Bernardes, Tiago, Pereira, Alexandre, Sousa, Patrícia, Filho, João G., Nazario, Nazare, Amaral, Odete, Garrido, António, Veiga, Nélio, Pedro, Ana R., Pereira, Carlos, Almeia, António, Fernandes, Helder M., Vasconcelos, Carlos, Sousa, Nelson, Reis, Victor M., Monteiro, M. João, Mendes, Romeu, Pinto, Isabel C., Pires, Tânia, Gama, João, Preto, Vera, Silva, Norberto, Magalhães, Carlos, Martins, Matilde, Duarte, Mafalda, Paúl, Constança, Martín, Ignácio, Pinheiro, Arminda A., Xavier, Sandra, Azevedo, Julieta, Bento, Elisabete, Marques, Cristiana, Marques, Mariana, Macedo, António, Pereira, Ana T., Almeida, José P., Almeida, António, Alves, Josiane, Saavedra, Francisco, Maia, Ana S., Oliveira, Michelle T., Sousa, Anderson R., Ferreira, Paulo P., Lopes, Luci S., Santiago, Eujcely C., Monteiro, Sílvia, Jesus, Ângelo, Colaço, Armanda, Carvalho, António, Silva, Rita P., Cruz, Agostinho, Ferreira, Ana, Marques, Catarina, Figueiredo, João P., Paixão, Susana, Lopes, Carla, Moreira, Fernando, Ribeiro, Diana, Fernandes, Telma, Amado, Diogo, Leal, Jéssica, Azevedo, Marcelo, Ramalho, Sónia, Mangas, Catarina, Ribeiro, Jaime, Gonçalves, Rita, Nunes, Amélia F, Tuna, Ana R., Martins, Carlos R., Forte, Henriqueta D., Costa, Cláudia, Tenedório, José A., Santana, Paula, Andrade, J.A., Pinto, J.L., Campofiorito, C., Nunes, S., Carmo, A., Kaliniczenco, A., Alves, B., Mendes, F., Jesus, C., Fonseca, F., Gehrke, F., Albuquerque, Carlos, Batista, Rita, Cunha, Madalena, Madureira, António, Ribeiro, Olivério, Martins, Rosa, Madeira, Teresa, Peixoto-Plácido, Catarina, Santos, Nuno, Santos, Osvaldo, Bergland, Astrid, Bye, Asta, Alarcão, Violeta, Goulão, Beatriz, Mendonça, Nuno, Nicola, Paulo, Clara, João G., Gomes, João, Querido, Ana, Tomás, Catarina, Carvalho, Daniel, Cordeiro, Marina, Rosa, Marlene C., Brandão, Daniela, Araújo, Lia, Minghelli, Beatriz, Richaud, Sylvina, Mendes, Ana L., Marta-Simões, Joana, Trindade, Inês A., Ferreira, Cláudia, Carvalho, Teresa, Pinto-Gouveia, José, Fernandes, Morgana C., Medeiros, Anabela, Pimentel, Rafaela, Fernandes, Andreia, Mendonça, Carlos, Andrade, Susana, Menezes, Ruth L., Bravo, Rafael, Miranda, Marta, Ugartemendia, Lierni, Tena, José Mª, Pérez-Caballero, Francisco L., Fuentes-Broto, Lorena, Rodríguez, Ana B., Carmen, Barriga, Carneiro, M.A., Domingues, J.N., Paixão, S., Figueiredo, J., Nascimento, V.B., Mendes, F, Azzalis, L., Martins, Ana R., Nunes, Amélia, Jorge, Arminda, Amorim, Ana, Silva, André, Martinho, Liliana, Monteiro, Luís, Silva, Rafael, Coelho, Carina, Coelho, Inês, Correia, André, Rodrigues, Diana, Marante, Nídia, Silva, Pedro, Carvalho, Sara, Araujo, André Rts, Ribeiro, Maximiano, Coutinho, Paula, Ventura, Sandra, Roque, Fátima, Calvo, Cristina, Reses, Manoela, Conde, Jorge, Figueiredo, João, Silva, David, Seiça, Luís, Soares, Raquel, Mourão, Ricardo, Kraus, Teresa, Abreu, Ana C., Padilha, José M., Alves, Júlia M., Sousa, Paulino, Oliveira, Manuel, Sousa, Joana, Novais, Sónia, Mendes, Felismina, Pinto, Joana, Cruz, Joana, Duarte, Hugo, Dixe, Maria Dos Anjos, Sousa, Pedro, Cruz, Inês, Bastos, Fernanda, Pereira, Filipe, Carvalho, Francisco L., Oliveira, Teresa T., Raposo, Vítor R., Ribeiro, José C., Barroso, Isabel, Rodrigues, Vítor, Neves, Carmo, Oliveira, Teresa C., Oliveira, Bárbara, Morais, Mª Carminda, Baylina, Pilar, Rodrigues, Rogério, Azeredo, Zaida, Vicente, Corália, Dias, Hélia, Sim-Sim, Margarida, Castilho, Amélia, Melo, Rosa, Graveto, João, Gomes, José, Vaquinhas, Marina, Carvalho, Carla, Mónico, Lisete, Brito, Nuno, Sarroeira, Cassilda, Amendoeira, José, Cunha, Fátima, Cândido, Anabela, Fernandes, Patrícia, Silva, Helena R., Silva, Elsa, Lapa, Leila, Antunes, Cristina, Gomes, Mª José, Escanciano, Susana R., Freitas, Maria, Marôco, João, Fernandes, Ana R., Cabral, Cremilde, Alves, Samuel, Ferreira, António, Príncipe, Fernanda, Seppänen, Ulla-Maija, Ferreira, Margarida, Carvalhais, Maribel, Silva, Marilene, Silva, Joana, Neves, Jéssica, Costa, Diana, Santos, Bruno, Duarte, Soraia, Marques, Sílvia, Mendes, Isabel, Louro, Clarisse, Menino, Eva, Dixe, Maria, Dias, Sara S., Valim, Frederico C., Costa, Joyce O., Bernardes, Lúcia G., Prebianchi, Helena, Rosa, Marlene Cristina, Gonçalves, Narcisa, Martins, Maria M., Kurcgant, Paulina, Vieira, André, Bento, Sandrina, Deodato, Sérgio, Rabiais, Isabel, Reis, Laura, Torres, Ana, Soares, Sérgio, Graça, Pedro, Leitão, Céu, Abreu, Renato, Bellém, Fernando, Almeida, Ana, Ribeiro-Varandas, Edna, Tavares, Ana, Henriques, Carolina, Jordão, Célia, Neco, Sofia, Morais, Carminda, Ferreira, Pedro, Silva, Carla R., Brito, Alice, Silva, Antónia, Postolache, Gabriela, Oliveira, Raul, Moreira, Isabel, Pedro, Luísa, Vicente, Sónia, Domingos, Samuel, Postolache, Octavian, Silva, Darlen, Schneider, Dulcineia, Marques, Fátima M., Pinto, Carlos, Vicente, Sara, Breda, São João, Gomes, José H., Salgueiro, Anabela, Duarte, Nuno, Lopes, José C., Nunes, Hélder, Braga, Luciene M., Araújo, Beatriz, Alves, José M., Sousa, Ana S., Ferrito, Cândida, Ferreira, Pedro L., Rodrigues, Alexandre, Oliveira, Isabel, Martins, Cristina, Macedo, Ana P., Araújo, Odete, Augusto, Cláudia, Braga, Fátima, Gomes, Lisa, Silva, Maria A., Rosário, Rafaela, Pimenta, Luís, Carreira, Diana, Teles, Patrícia, Barros, Teresa, Jácome, Cristina, Capelas, Sylvie, Hall, Andreia, Alves, Dina, Lousada, Marisa, Loureiro, Mª Helena, Camarneiro, Ana, Silva, Margarida, Mendes, Aida, Pedreiro, Ana, G. Silva, Anne, Coelho, Elza S., Melo, Flávio, Ribeiro, Fernando, Torres, Rui, Costa, Rui, Pinho, Tânia, Cruz, Bárbara, Carreiras, Diogo, Ventura, Maria, Cruz, x, Brooks, Dina, Pinto, M Rosário, Lima-Basto, Marta, Neves, Miguel, Bizarro, Carla, Margarida, Couto, Amorim, Ana P., Silva, Eduardo, Cruz, Susana, Valente, Jorge, Guerrero, José T., Gonzalez, Estefania P., Monago, Fátima M., Ugalde, Lierni U., Vélez, Marta M., Tena, Maria J., Becerra, Isabel A., Agudelo, Mª Elizabeth, Acedo, Guadalupe, Bajo, Roberto, Malheiro, Isabel, Gaspar, Filomena, Barros, Luísa, Furtado, Guilherme, Uba-Chupel, Mateus, Rama, Luís, Braga, Margarida, Ferreira, José P., Teixeira, Ana Mª, Cruz, João, Barbosa, Tiago, Simões, Ângela, Coelho, Luís, Martinez-Hernandez, Francisco, Rodriguez-De-Vera, Bienvenida, Rodrigues, Alexandrina, Ramalho, André, Petrica, João, Mendes, Pedro, Serrano, João, Santo, Inês, Rosado, António, Mendonça, Paula, Freitas, Kátia, Ferreira, Dora, Brito, António, Fernandes, Renato, Gomes, Sofia, Pinho, Cláudia, Oliveira, Rita, Oliveira, Ana I., Casimiro, Ana P., Martins, Patrícia, Silva, Iryna, Evangelista, Diana, Leitão, Catarina, Velosa, Fábia, Carecho, Nélio, Dixe, Anjos, Catarino, Helena, Soares, Fátima, Gama, Ester, Gordo, Clementina, Moreira, Eliana, Midões, Cristiana, Santos, Marlene, Machado, Sara, Oliveira, Vânia P., Marques, Rita, Charepe, Zaida, Antunes, Ana, Santos, Sofia, Marques, Silvana F., CaroMinghelli, Eulália, Luís, Mª José, Brandão, Teresa, Marinho, Daniel, Monteiro, Diogo, Paulo, Rui, Monteiro, Lina, Ramalho, Fátima, Santos-Rocha, Rita, Morgado, Sónia, Bento, Teresa, Silva, Isabel, Azevedo, Tatiana, Soares, Salete, Pisco, Jacinta, Olszewer, Efrain O., Oliveira, Sebastião T., Santos, Erica, Maia, Carla, Mendes, Maria F., Oliveira, Rita F., Barreira, Eduarda, Pereira, Ana, Vaz, Josiana A., Novo, André, Silva, Luís D., Maia, Bruno, Ferreira, Eduardo, Pires, Filipa, Andrade, Renato, Camarinha, Luís, César, Ana F., Poço, Mariana, Ventura, David, Loura, Raquel, Gomes, Pedro, Gomes, Catarina, Silva, Cláudia, Melo, Elsa, Lindo, João, Domingos, Joana, Mendes, Zaida, Poeta, Susana, Carvalho, Tiago, Dixe, Mª Anjos, Garcia, Inês, Meneses, Rui, Afonso, Carlos, Faria, Luís, Seixas, Adérito, Granjo, Paulo, Gomes, José C., Souza, Nelba R., Furtado, Guilherme E., Rocha, Saulo V., Silva, Paula, Carvalho, Joana, Morais, Marina Ana, Lebre, Paula, Alencar, Liana, Cardoso, Ilda, Daniel, Fernanda, Luz, Tatiana, Ramos, Maurício R., Medeiros, Dayse C., Carmo, Bruno M., Seabra, André, Padez, Cristina, Silva, Manuel C., Rodrigues, António, Coelho, Alexandre, Caminha, Madson, Matheus, Filipe, Mendes, Elenice, Correia, Jony, Rodriguez-De-Vera, Bienvendida C., Jimenez-Rodriguez, Carla, Armas-Gonzalez, Yadira, Rodrigues, Cátia, Pedroso, Rosa, Apolinário-Hagen, Jennifer, Vehreschild, Viktor, Veloso, Milene, Magalhães, Celina, Cabral, Isabel, Ferraz, Maira, Nave, Filipe, Costa, Emília, Matos, Filomena, Pacheco, José, Dias, António, Duarte, João, Silva, Daniel, Alferes, Valentim R., Brêda, Mª São João, Parreira, Pedro M., Pimenta, Rui, Boavida, José, Silva, Catarina, Ribeiro, Maria, Viega-Branco, Maria, Pereira, Filomena, Almeida, Fabrícia M., Estevez, Gustavo L., Kretzer, Marcia R., João, Paulo V., Nogueira, Paulo, Novais, Sandra, Carneiro, Lara, Mota, Maria, Santiago, Luiz, Fontes-Ribeiro, Carlos, Coutinho, André P., Neto, João S., Vasconcelos, Lélia R., Dantas, Estélio, Dinis, Alexandra, Carvalho, Sérgio, Castilho, Paula, Sarreira-Santos, Alexandra, Figueiredo, Amélia, Medeiros-Garcia, Lurdes, Seabra, Paulo, Rodrigues, Rosa, Fernandes, Paula O., Santiago, Conceição, Figueiredo, Mª Henriqueta, Guimarães, Teresa, Coelho, André, Graça, Anabela, Silva, Ana M., Fonseca, Ana R., Vale-Dias, Luz, Minas, Bárbara, Franco-Borges, Graciete, Simões, Cristina, Serra, Ana, Matos, Maria, Jesus, Luís, Tavares, Ana S., Varandas, Edna, Miranda, Cristiana, Guimarães, Pedro, Gonçalves, Rodrigo, San-Martin, Elisabete A., Goulart, Cássia L., Schneiders, Paloma B., Miranda, Natacha F., Silva, Andrea G., Topa, Joana, Nogueira, Conceição, Neves, Sofia, Ventura, Rita, Nazaré, Cristina, Freitas, Alberto, Mercê, Cristiana, Branco, Marco, Almeida, Pedro, Nascimento, Daniela, Pereira, Juliana, Catela, David, Rafael, Helga, Reis, Alcinda C., Mendes, Ana, Valente, Ana R., Sousa, Diana, Baltazar, Ana L., Oliveira, Ana, Aparício, José, Neves, Joana, Ayoub, Rodrigo, Sousa, Luís, Marques-Vieira, Cristina, Severino, Sandy, José, Helena, Cadorio, Inês, Andrade, Diogo, Domingues, Cátia, Schukg, Susann, Abrantes, Ana M., Gonçalves, Ana C., Sales, Tiago, Teixo, Ricardo, Estrela, Jéssica, Laranjo, Mafalda, Casalta-Lopes, João, Rocha, Clara, Simões, Paulo C., Sarmento-Ribeiro, Ana B., Botelho, Mª Filomena, Rosa, Manuel S., Fonseca, Virgínia, Colaço, Diogo, Neves, Vanessa, Jesus, Carlos, Hesse, Camilla, Svensson, Lola, Siba, Wafa A., Pereira, Cristina, Tomaz, Jorge, Duarte, Diana, Lopes, Nuno V., Fonseca-Pinto, Rui, Brandão, Piedade, Martins, Laura, Cardoso, Margarida, Morais, Nuno, Alves, Nuno, Faria, Paula, Mateus, Artur, Morouço, Pedro, Ferreira, Nelson, Cardoso, Andreia, Lopes, Albino, Soares, Valter, Dias, Tiago, Vardasca, Ricardo, Gabriel, Joaquim, Paredes, Hugo, Reis, Arsénio, Marinho, Sara, Filipe, Vítor, Lains, Jorge, Barroso, João, Da Motta, Carolina, Carvalho, Célia B., Peixoto, Ermelindo, Gomes, Ana A., Costa, Vanessa, Couto, Diana, Marques, Daniel R., Leitão, José A., Tavares, José, Azevedo, Maria H., Silva, Carlos F., Freitas, João, Garcia-Gordillo, Miguel A., Collado-Mateo, Daniel, Chen, Gang, Iezzi, Angelo, Sala, José A., Parraça, José A., Gusi, Narcis, Sousa, Jani, Jardim, Jacinto, Pereira, Anabela, Simões, Sónia, Sardo, Pedro, Guedes, Jenifer, Machado, Paulo, Benevides, Joana, Sousa, Marina, Cabral, Joana, Carvalho, Rosa, Alves, Juliana, Azevedo, Mª Helena, Silva, Carlos, Lee, Huei D., Spolaôr, Newton, Oliva, Jefferson T., Chung, Wu F., Bairros, Keila, Silva, Cláudia D., Souza, Clóvis A., Schroeder, Silvana S., Araújo, Elsa, Monteiro, Helena, Costa, Ricardo, Torgal, Jorge, Henriques, Carolina G., Santos, Luísa, Caceiro, Elisa F., Ramalho, Sónia A., Afreixo, Vera, Santos, João, Mota, Priscilla, Pimentel, Francisco, Caldeira, Suzana N., Ribeiro, Lígia C., Aquino, Priscila S., Ribeiro, Samila G., Pinheiro, Ana B., Lessa, Paula A., Oliveira, Mirna F., Brito, Luísa S., Pinto, Ítalo N., Furtado, Alessandra S., Castro, Régia B., Aquino, Caroline Q., Martins, Eveliny S., Pinheiro, Ana B, Oliveira, Lara L., Pinheiro, Patrícia C., Sousa, Caroline R., Freitas, Vívien A., Silva, Tatiane M., Lima, Adman S., Andrade, Karizia V., Oliveira, Camila A., Vidal, Eglidia F., Ganho-Ávila, Ana, Moura-Ramos, Mariana, Gonçalves, Óscar, Almeida, Jorge, Silva, Armando, Brito, Irma, Amado, João, Rodrigo, António, Gomes, Fernando, Luís, Sara, Cavalheiro, Luís, Gonçalves, Rui, Lopes, Rui S., Fiorin, Bruno H., Santos, Marina S., Oliveira, Edmar S., Moreira, Rita L., Oliveira, Elizabete A., Filho, Braulio L., Palmeira, Lara, Garcia, Teresa, Cardoso, Sara, Oliveira, Sara, Campos, Mariana, Gaudêncio, Iris, Martins, Fernando, Ferreira, Lino, Lopes, Nuno, Marques, Ana R., Carvalho, Rui, Costa, Pablo O., Silva, Maiza M., Alvarenga-Martins, Nathália, Pinto, Paulo F., Oliveira, Denize C., Parreira, Pedro D., Gomes, Antônio T., Lage, Isabel, Cabrita, José, Teixeira, Laetitia, Silva, Sara, Cordeiro, Eugénio, Pimentel, João, Ferro-Lebres, Vera, Souza, Juliana A., Tavares, Mariline, Passadouro, Rui, Peralta, Teresa, Ferreira, Carlos, Lourenço, Georgina, Honório, Samuel, Simões, Alexandra, Carvalho, Lucinda, Figueiredo, Daniela, Valente, Carolina, Ribas, Patrícia, Brandão, Frederico, Sousa, Cesar, Mendes, Francisco, Fernandes, Rosina, Martins, Emília, Magalhães, Cátia, Araújo, Patrícia, Grande, Carla, Vieitez, Juan G., Bianchini, Bruna, Costa, Tânia, Almeida, Armando, Baffour, Gabriel, Laranjeira, Carlos, Guerra, Magda, Barbeiro, Ana P., Ferreira, Regina, Lopes, Sara, Nunes, Liliana, Martins, Julian, Magajewski, Flávio, Soares, Célia, Marques, António, Batista, Marco, Castuera, Ruth J., Mesquita, Helena, Faustino, António, Santos, Jorge, Vizzotto, Betina P., Frigo, Leticia, Pivetta, Hedioneia F., Sardo, Dolores, Abreu, Wilson, Figueiredo, Mª Céu, Jimenez-Castuera, Ruth, Silveira, Paulo, Oliveira, Catarina, Rodriguez, Cláudia K., Kretzer, Márcia R., Nazário, Nazaré O., Cruz, Pedro, Vaz, Daniela C., Ruben, Rui B., Avelelas, Francisco, Silva, Susana, Campos, Mª Jorge, Almeida, Maria, Gonçalves, Liliana, Antunes, Lígia, Simões, João, Cardoso, Susana, Loureiro, Isabel, Santos, Flávia, Alves, Gilberto, Soar, Cláudia, Marsi, Teresa O., Silva, Ernestina, Pedrosa, Dora, Leça, Andrea, Gomes, Maria, Fernandes, Paula, Noné, Ana, Combadão, Jaime, Ramalhete, Cátia, Figueiredo, Paulo, Caeiro, Patrícia, Fontana, Karine C., Machado, Patrícia O., Borges, Raphaelle, Barbosa, Flávio, Sá, Dayse, Brunhoso, Germana, Aparício, Graça, Carvalho, Amâncio, Garcia, Ana P., Santos, Adriana, Brás, Carina, Carvalho, Inês, Batalha, Joana, Glória, Margarida, Bexiga, Filipa, Paraíso, Nilson, Lima, Cristóvão F., Dias, Alberto P., Espada, Mário, Marques, Mário, Veiga-Branco, Mª, Lima, Vera, Cruz, Graça, Barreiros, Luísa, Duarte, Catarina, Lima, Teresa Maneca, Medina, María S., Blanco, Valeriana G., Lopes, Elisa, Virgolino, Ana, Ambrósio, Sara, Almeida, Inês, Marques, Tatiana, Heitor, Mª João, Olivares, Pedro R., Oliveira, Anabela, Cheio, Mónica, Pereira, Olívia R., Pinto, Sara, Oliveira, Adriana, Manso, M. Conceição, Sousa, Carla, Vinha, Ana F., Machado, Mª Manuela, Vieira, Margarida, Fernandes, Beatriz, Tomás, Teresa, Quirino, Diogo, Desouzart, Gustavo, Matos, Rui, Bordini, Magali, Mouroço, Pedro, Matos, Ana R., Serapioni, Mauro, Costa, André, Ribeiro, João, Lobato, João, Martin, Inmaculada Z., Björklund, Anita, Tavares, Aida I., Tavares, Nuno, Valente, João, Ortiga, Angela B., Calvo, Mª Cristina, Natal, Sônia, Pereira, Marta, Prata, Ana R., Nelas, Paula, Carneiro, Juliana, Couto, Cristina, Souza, Géssica M., Almada, Lívia F., Conceição, Milena A., Domingues, Gabriela, Ferreira, Irina, Costa, Ana R., Cardoso, Américo, Meireles, Alexandra, Vieira, Viviane L., Vincha, Kellem R., Cervato-Mancuso, Ana Mª, Faria, Melissa, Reis, Cláudia, Cova, Marco P., Ascenso, Rita T., Almeida, Henrique A., Oliveira, Eunice G., Santana, Miguel, Pereira, Rafael, Jesus, Rita, Tapadas, Rodrigo, Tim-Tim, Carolina, Cezanne, Catarina, Lagoa, Matilde, Lopes, João, Almeida, Henrique, Amado, Sandra, Carrão, Luís, Saboga-Nunes, Luís, Oliveira, Suzete, Escoval, Ana, Assunção, Victor, Luís, Henrique, Luís, Luís, Fotschl, Ulrike, Lirk, Gerald, Silva, Paula A., Ruivo, Joana, Silva, Vânia, Ferraz, Vera, Neves, Joel, Correia, Telma, Amorim, Helena, Pereira, Elsa S., Santos, Leonino S., Reis, Ana S., Rombo, João, Fernandes, Jorge C., Freire, Ana, Francisco, Irene, Louro, Mª Clarisse, Lopes, Saudade, Oliveira, Ana P., Gordo, Sara, Queirós, Paulo, Rodrigues, Teresa, Lobão, Catarina, Moura, Cynthia B., Dreyer, Laysa C., Meneghetti, Vanize, Cabral, Priscila P., Pinto, Francisca, Esteves, Mª Raquel, Galvão, Sofia, Tytgat, Ite, Casas-Novas, Mónica, Bernardo, Helena, Sousa, Gracinda, Sousa, Ana P., Belo, Pedro, Martins, Fátima, Pulido-Fuentes, Montserrat, Cabral, Gil, Prado, Alessandro, Carvalho, Yara M., Campos, Maria, Moreira, Liliana, Ferreira, José, and Teixeira, Ana

Abstract

S1 Health literacy and health education in adolescence

Published
2016

14. Filling gaps on ivermectin knowledge: effects on the survival and reproduction of Anopheles aquasalis, a Latin American malaria vector.

Author

Sampaio, Vanderson S., Beltrán, Tatiana P., Kobylinski, Kevin C., Melo, Gisely C., Lima, José B. P., Silva, Sara G. M., Rodriguez, Íria C., Silveira, Henrique, Guerra, Maria G. V. B., Bassat, Quique, Pimenta, Paulo F. P., Lacerda, Marcus V. G., and Monteiro, Wuelton M.

Subjects
MALARIA treatment, INFECTION treatment, PREVENTION of infectious disease transmission, IVERMECTIN, MOSQUITOES
Abstract

Background: Strategies designed to advance towards malaria elimination rely on the detection and treatment of infections, rather than fever, and the interruption of malaria transmission between mosquitoes and humans. Mass drug administration with anti-malarials directed at eliminating parasites in blood, either to entire populations or targeting only those with malaria infections, are considered useful strategies to progress towards malaria elimination, but may be insufficient if applied on their own. These strategies assume a closer contact with populations, so incorporating a vector control intervention tool to those approaches could significantly enhance their efficacy. Ivermectin, an endectocide drug efficacious against a range of Anopheles species, could be added to other drug-based interventions. Interestingly, ivermectin could also be useful to target outdoor feeding and resting vectors, something not possible with current vector control tools, such as impregnated bed nets or indoor residual spraying (IRS). Results: Anopheles aquasalis susceptibility to ivermectin was assessed. In vivo assessments were performed in six volunteers, being three men and three women. The effect of ivermectin on reproductive fitness and mosquito survivorship using membrane feeding assay (MFA) and direct feeding assay (DFA) was assessed and compared. The ivermectin lethal concentration (LC) values were LC50 = 47.03 ng/ml [44.68-49.40], LC25 = 31.92 ng/ml [28.60-34.57] and LC5 = 18.28 ng/ml [14.51-21.45]. Ivermectin significantly reduced the survivorship of An. aquasalis blood-fed 4 h post-ingestion (χ² [N = 880] = 328.16, p < 0.001), 2 days post-ingestion (DPI 2) (χ² [N = 983] = 156.75, p < 0.001), DPI 7 (χ² [N = 935] = 31.17, p < 0.001) and DPI 14 (χ² [N = 898] = 38.63, p < 0.001) compared to the blood fed on the untreated control. The average number of oviposited eggs per female was significantly lower in LC5 group (22.44 [SD = 3.38]) than in control (34.70 [SD = 12.09]) (χ² [N = 199] = 10.52, p < 0.001) as well as the egg hatch rate (LC5 = 74.76 [SD = 5.48]) (Control = 81.91 [SD = 5.92]) (χ² [N = 124] = 64.24, p < 0.001). However, no differences were observed on the number of pupae that developed from larvae (Control = 34.19 [SD = 10.42) and group (LC5 = 33.33 [SD = 11.97]) (χ² [N = 124] = 0.96, p > 0.05). Conclusions: Ivermectin drug reduces mosquito survivorship when blood fed on volunteer blood from 4 h to 14 days post-ingestion controlling for volunteers' gender. Ivermectin at mosquito sub-lethal concentrations (LC5) reduces fecundity and egg hatch rate but not the number of pupae that developed from larvae. DFA had significantly higher effects on mosquito survival compared to MFA. The findings are presented and discussed through the prism of malaria elimination in the Amazon region. [ABSTRACT FROM AUTHOR]

Published
2016
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15. EURISWEB - Web-based epidemiological surveillance of antibiotic-resistant pneumococci in Day Care Centers.

Author

Silva, Sara, Gouveia-Oliveira, Rodrigo, Maretzek, António, Carriço, João, Gudnason, Thorolfur, Kristinsson, Karl G., Ekdahl, Karl, Brito-Avô, António, Tomasz, Alexander, Sanches, Ilda Santos, de Lencastre, Hermínia, and Almeida, Jonas

Subjects
*EPIDEMIOLOGICAL research, *ANTIBIOTICS, *STREPTOCOCCUS pneumoniae, *DAY care centers, *JUVENILE diseases, *ONLINE databases, *WEB development
Abstract

Background: EURIS (European Resistance Intervention Study) was launched as a multinational study in September of 2000 to identify the multitude of complex risk factors that contribute to the high carriage rate of drug resistant Streptococcus pneumoniae strains in children attending Day Care Centers in several European countries. Access to the very large number of data required the development of a web-based infrastructure -- EURISWEB -- that includes a relational online database, coupled with a query system for data retrieval, and allows integrative storage of demographic, clinical and molecular biology data generated in EURIS. Methods: All components of the system were developed using open source programming tools: data storage management was supported by PostgreSQL, and the hypertext preprocessor to generate the web pages was implemented using PHP. The query system is based on a software agent running in the background specifically developed for EURIS. Results: The website currently contains data related to 13,500 nasopharyngeal samples and over one million measures taken from 5,250 individual children, as well as over one thousand pre-made and user-made queries aggregated into several reports, approximately. It is presently in use by participating researchers from three countries (Iceland, Portugal and Sweden). Conclusion: An operational model centered on a PHP engine builds the interface between the user and the database automatically, allowing an easy maintenance of the system. The query system is also sufficiently adaptable to allow the integration of several advanced data analysis procedures far more demanding than simple queries, eventually including artificial intelligence predictive models. [ABSTRACT FROM AUTHOR]

Published
2003
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16. Infection of <italic>Anopheles aquasalis</italic> from symptomatic and asymptomatic <italic>Plasmodium vivax</italic> infections in Manaus, western Brazilian Amazon.

Author

Martins-Campos, Keillen M., Kuehn, Andrea, Almeida, Anne, Duarte, Ana Paula M., Sampaio, Vanderson S., Rodriguez, Íria C., da Silva, Sara G. M., Ríos-Velásquez, Claudia María, Lima, José Bento Pereira, Pimenta, Paulo Filemon Paolucci, Bassat, Quique, Müller, Ivo, Lacerda, Marcus, Monteiro, Wuelton M., and Barbosa Guerra, Maria das Graças V.

Subjects
PLASMODIUM vivax, ANOPHELES, MALARIA prevention, POLYMERASE chain reaction, GERM cells, OOCYSTS
Abstract

Background: Asymptomatic individuals are one of the major challenges for malaria elimination programs in endemic areas. In the absence of clinical symptoms and with a lower parasite density they constitute silent reservoirs considered important for maintaining transmission of human malaria. Studies from Brazil have shown that infected individuals may carry these parasites for long periods. Results: Patients were selected from three periurban endemic areas of the city of Manaus, in the western Brazilian Amazon. Symptomatic and asymptomatic patients with positive thick blood smear and quantitative real-time PCR (qPCR) positive for Plasmodium vivax were invited to participate in the study. A standardised pvs25 gene amplification by qPCR was used for P. vivax gametocytes detection. Anopheles aquasalis were fed using membrane feeding assays (MFA) containing blood from malaria patients. Parasitemia of 42 symptomatic and 25 asymptomatic individuals was determined by microscopic examination of blood smears and qPCR. Parasitemia density and gametocyte density were assessed as determinants of infection rates and oocysts densities. A strong correlation between gametocyte densities (microscopy and molecular techniques) and mosquito infectivity (P < 0.001) and oocysts median numbers (P < 0.05) was found in both groups. The ability to infect mosquitoes was higher in the symptomatic group (41%), but infectivity in the asymptomatic group was also seen (1.42%). Conclusions: Although their infectivity to mosquitoes is relatively low, given the high prevalence of P. vivax asymptomatic carriers they are likely to play and important role in malaria transmission in the city of Manaus. The role of asymptomatic infections therefore needs to be considered in future malaria elimination programs in Brazil. [ABSTRACT FROM AUTHOR]

Published
2018
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