44 results on '"Petersen, Steffen E."'
Search Results
2. Society for Cardiovascular Magnetic Resonance (SCMR) guidelines for reporting cardiovascular magnetic resonance examinations
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Hundley, W. Gregory, Bluemke, David A., Bogaert, Jan, Flamm, Scott D., Fontana, Marianna, Friedrich, Matthias G., Grosse-Wortmann, Lars, Karamitsos, Theodoros D., Kramer, Christopher M., Kwong, Raymond Y., McConnell, Michael, Nagel, Eike, Neubauer, Stefan, Nijveldt, Robin, Pennell, Dudley J., Petersen, Steffen E., Raman, Subha V., and van Rossum, Albert
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- 2022
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3. Evidence-based cardiovascular magnetic resonance cost-effectiveness calculator for the detection of significant coronary artery disease
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Pandya, Ankur, Yu, Yuan-Jui, Ge, Yin, Nagel, Eike, Kwong, Raymond Y., Bakar, Rafidah Abu, Grizzard, John D., Merkler, Alexander E., Ntusi, Ntobeko, Petersen, Steffen E., Rashedi, Nina, Schwitter, Juerg, Selvanayagam, Joseph B., White, James A., Carr, James, Raman, Subha V., Simonetti, Orlando P., Bucciarelli-Ducci, Chiara, Sierra-Galan, Lilia M., Ferrari, Victor A., Bhatia, Mona, and Kelle, Sebastian
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- 2022
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4. Cardiovascular magnetic resonance reference values of mitral and tricuspid annular dimensions: the UK Biobank cohort
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Ricci, Fabrizio, Aung, Nay, Gallina, Sabina, Zemrak, Filip, Fung, Kenneth, Bisaccia, Giandomenico, Paiva, Jose Miguel, Khanji, Mohammed Y., Mantini, Cesare, Palermi, Stefano, Lee, Aaron M., Piechnik, Stefan K., Neubauer, Stefan, and Petersen, Steffen E.
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- 2021
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5. NHS Health Check attendance is associated with reduced multiorgan disease risk: a matched cohort study in the UK Biobank.
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McCracken, Celeste, Raisi-Estabragh, Zahra, Szabo, Liliana, Robson, John, Raman, Betty, Topiwala, Anya, Roca-Fernández, Adriana, Husain, Masud, Petersen, Steffen E., Neubauer, Stefan, and Nichols, Thomas E.
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HEART failure ,FATTY liver ,COHORT analysis ,MYOCARDIAL infarction ,CHRONIC kidney failure ,ACUTE kidney failure ,DISEASE incidence - Abstract
Background: The NHS Health Check is a preventive programme in the UK designed to screen for cardiovascular risk and to aid in primary disease prevention. Despite its widespread implementation, the effectiveness of the NHS Health Check for longer-term disease prevention is unclear. In this study, we measured the rate of new diagnoses in UK Biobank participants who underwent the NHS Health Check compared with those who did not. Methods: Within the UK Biobank prospective study, 48,602 NHS Health Check recipients were identified from linked primary care records. These participants were then covariate-matched on an extensive range of socio-demographic, lifestyle, and medical factors with 48,602 participants without record of the check. Follow-up diagnoses were ascertained from health records over an average of 9 years (SD 2 years) including hypertension, diabetes, hypercholesterolaemia, stroke, dementia, myocardial infarction, atrial fibrillation, heart failure, fatty liver disease, alcoholic liver disease, liver cirrhosis, liver failure, acute kidney injury, chronic kidney disease (stage 3 +), cardiovascular mortality, and all-cause mortality. Time-varying survival modelling was used to compare adjusted outcome rates between the groups. Results: In the immediate 2 years after the NHS Health Check, higher diagnosis rates were observed for hypertension, high cholesterol, and chronic kidney disease among health check recipients compared to their matched counterparts. However, in the longer term, NHS Health Check recipients had significantly lower risk across all multiorgan disease outcomes and reduced rates of cardiovascular and all-cause mortality. Conclusions: The NHS Health Check is linked to reduced incidence of disease across multiple organ systems, which may be attributed to risk modification through earlier detection and treatment of key risk factors such as hypertension and high cholesterol. This work adds important evidence to the growing body of research supporting the effectiveness of preventative interventions in reducing longer-term multimorbidity. [ABSTRACT FROM AUTHOR]
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- 2024
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6. Right ventricular shape and function: cardiovascular magnetic resonance reference morphology and biventricular risk factor morphometrics in UK Biobank
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Mauger, Charlène, Gilbert, Kathleen, Lee, Aaron M., Sanghvi, Mihir M., Aung, Nay, Fung, Kenneth, Carapella, Valentina, Piechnik, Stefan K., Neubauer, Stefan, Petersen, Steffen E., Suinesiaputra, Avan, and Young, Alistair A.
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- 2019
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7. Automated quality control in image segmentation: application to the UK Biobank cardiovascular magnetic resonance imaging study
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Robinson, Robert, Valindria, Vanya V., Bai, Wenjia, Oktay, Ozan, Kainz, Bernhard, Suzuki, Hideaki, Sanghvi, Mihir M., Aung, Nay, Paiva, José Miguel, Zemrak, Filip, Fung, Kenneth, Lukaschuk, Elena, Lee, Aaron M., Carapella, Valentina, Kim, Young Jin, Piechnik, Stefan K., Neubauer, Stefan, Petersen, Steffen E., Page, Chris, Matthews, Paul M., Rueckert, Daniel, and Glocker, Ben
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- 2019
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8. Society for Cardiovascular Magnetic Resonance (SCMR) expert consensus for CMR imaging endpoints in clinical research: part I - analytical validation and clinical qualification
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Puntmann, Valentina O., Valbuena, Silvia, Hinojar, Rocio, Petersen, Steffen E., Greenwood, John P., Kramer, Christopher M., Kwong, Raymond Y., McCann, Gerry P., Berry, Colin, Nagel, Eike, and on behalf of SCMR Clinical Trial Writing Group
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- 2018
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9. Automated cardiovascular magnetic resonance image analysis with fully convolutional networks
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Bai, Wenjia, Sinclair, Matthew, Tarroni, Giacomo, Oktay, Ozan, Rajchl, Martin, Vaillant, Ghislain, Lee, Aaron M., Aung, Nay, Lukaschuk, Elena, Sanghvi, Mihir M., Zemrak, Filip, Fung, Kenneth, Paiva, Jose Miguel, Carapella, Valentina, Kim, Young Jin, Suzuki, Hideaki, Kainz, Bernhard, Matthews, Paul M., Petersen, Steffen E., Piechnik, Stefan K., Neubauer, Stefan, Glocker, Ben, and Rueckert, Daniel
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- 2018
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10. Automated quality control in image segmentation: application to the UK Biobank cardiac MR imaging study
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Robinson, Robert, Valindria, Vanya V., Bai, Wenjia, Oktay, Ozan, Kainz, Bernhard, Suzuki, Hideaki, Sanghvi, Mihir M., Aung, Nay, Paiva, Jos$é$ Miguel, Zemrak, Filip, Fung, Kenneth, Lukaschuk, Elena, Lee, Aaron M., Carapella, Valentina, Kim, Young Jin, Piechnik, Stefan K., Neubauer, Stefan, Petersen, Steffen E., Page, Chris, Matthews, Paul M., Rueckert, Daniel, Glocker, Ben, Engineering & Physical Science Research Council (EPSRC), GlaxoSmithKline, National Institute for Health Research, UK DRI Ltd, Commission of the European Communities, and Innovate UK
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FOS: Computer and information sciences ,Population imaging ,Nuclear Medicine & Medical Imaging ,Segmentation ,Computer Vision and Pattern Recognition (cs.CV) ,Computer Science - Computer Vision and Pattern Recognition ,Automatic quality control ,1102 Cardiovascular Medicine And Haematology ,cs.CV - Abstract
Background: The trend towards large-scale studies including population imaging poses new challenges in terms of quality control (QC). This is a particular issue when automatic processing tools, e.g. image segmentation methods, are employed to derive quantitative measures or biomarkers for later analyses. Manual inspection and visual QC of each segmentation isn't feasible at large scale. However, it's important to be able to automatically detect when a segmentation method fails so as to avoid inclusion of wrong measurements into subsequent analyses which could lead to incorrect conclusions. Methods: To overcome this challenge, we explore an approach for predicting segmentation quality based on Reverse Classification Accuracy, which enables us to discriminate between successful and failed segmentations on a per-cases basis. We validate this approach on a new, large-scale manually-annotated set of 4,800 cardiac magnetic resonance scans. We then apply our method to a large cohort of 7,250 cardiac MRI on which we have performed manual QC. Results: We report results used for predicting segmentation quality metrics including Dice Similarity Coefficient (DSC) and surface-distance measures. As initial validation, we present data for 400 scans demonstrating 99% accuracy for classifying low and high quality segmentations using predicted DSC scores. As further validation we show high correlation between real and predicted scores and 95% classification accuracy on 4,800 scans for which manual segmentations were available. We mimic real-world application of the method on 7,250 cardiac MRI where we show good agreement between predicted quality metrics and manual visual QC scores. Conclusions: We show that RCA has the potential for accurate and fully automatic segmentation QC on a per-case basis in the context of large-scale population imaging as in the UK Biobank Imaging Study., Comment: 14 pages, 7 figures, Journal of Cardiovascular Magnetic Resonance
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- 2019
11. The science of clinical practice: disease diagnosis or patient prognosis? Evidence about 'what is likely to happen' should shape clinical practice
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Croft, Peter, Altman, Douglas G, Deeks, Jonathan J, Dunn, Kate M, Hay, Alastair D, Hemingway, Harry, LeResche, Linda, Peat, George, Perel, Pablo, Petersen, Steffen E, Riley, Richard D, Roberts, Ian, Sharpe, Michael, Stevens, Richard J, Van Der Windt, Danielle A, Von Korff, Michael, and Timmis, Adam
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Medicine(all) ,Opinion ,Evidence-based medicine ,Overdiagnosis ,Decision Making ,Outcomes of care ,Professional Practice ,Stratified medicine ,Prognosis ,Contested diagnoses ,R1 ,Information ,Diagnosis ,Humans ,Diagnostic Errors ,Clinical decision-making - Abstract
BACKGROUND: Diagnosis is the traditional basis for decision-making in clinical practice. Evidence is often lacking about future benefits and harms of these decisions for patients diagnosed with and without disease. We propose that a model of clinical practice focused on patient prognosis and predicting the likelihood of future outcomes may be more useful. DISCUSSION: Disease diagnosis can provide crucial information for clinical decisions that influence outcome in serious acute illness. However, the central role of diagnosis in clinical practice is challenged by evidence that it does not always benefit patients and that factors other than disease are important in determining patient outcome. The concept of disease as a dichotomous 'yes' or 'no' is challenged by the frequent use of diagnostic indicators with continuous distributions, such as blood sugar, which are better understood as contributing information about the probability of a patient's future outcome. Moreover, many illnesses, such as chronic fatigue, cannot usefully be labelled from a disease-diagnosis perspective. In such cases, a prognostic model provides an alternative framework for clinical practice that extends beyond disease and diagnosis and incorporates a wide range of information to predict future patient outcomes and to guide decisions to improve them. Such information embraces non-disease factors and genetic and other biomarkers which influence outcome. SUMMARY: Patient prognosis can provide the framework for modern clinical practice to integrate information from the expanding biological, social, and clinical database for more effective and efficient care.
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- 2015
12. Reference ranges for cardiac structure and function using cardiovascular magnetic resonance (CMR) in Caucasians from the UK Biobank population cohort.
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Petersen, Steffen E., Nay Aung, Sanghvi, Mihir M., Zemrak, Filip, Fung, Kenneth, Miguel Paiva, Jose, Francis, Jane M., Khanji, Mohammed Y., Lukaschuk, Elena, Lee, Aaron M., Carapella, Valentina, Young Jin Kim, Leeson, Paul, Piechnik, Stefan K., and Neubauer, Stefan
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HEART atrium , *HEART ventricles , *AGE distribution , *STATISTICAL correlation , *LEFT heart ventricle , *HEART physiology , *RIGHT heart ventricle , *MAGNETIC resonance imaging , *REFERENCE values , *RESEARCH funding , *SEX distribution , *T-test (Statistics) , *WHITE people , *DATA analysis software , *STROKE volume (Cardiac output) , *INTRACLASS correlation , *PHYSIOLOGY , *ANATOMY - Abstract
Background: Cardiovascular magnetic resonance (CMR) is the gold standard method for the assessment of cardiac structure and function. Reference ranges permit differentiation between normal and pathological states. To date, this study is the largest to provide CMR specific reference ranges for left ventricular, right ventricular, left atrial and right atrial structure and function derived from truly healthy Caucasian adults aged 45-74. Methods: Five thousand sixty-five UK Biobank participants underwent CMR using steady-state free precession imaging at 1.5 Tesla. Manual analysis was performed for all four cardiac chambers. Participants with non-Caucasian ethnicity, known cardiovascular disease and other conditions known to affect cardiac chamber size and function were excluded. Remaining participants formed the healthy reference cohort; reference ranges were calculated and were stratified by gender and age (45-54, 55-64, 65-74). Results: After applying exclusion criteria, 804 (16.²%) participants were available for analysis. Left ventricular (LV) volumes were larger in males compared to females for absolute and indexed values. With advancing age, LV volumes were mostly smaller in both sexes. LV ejection fraction was significantly greater in females compared to males (mean ± standard deviation [SD] of 61 ± 5% vs 58 ± 5%) and remained static with age for both genders. In older age groups, LV mass was lower in men, but remained virtually unchanged in women. LV mass was significantly higher in males compared to females (mean ± SD of 53 ± 9 g/m² vs 4² ± 7 g/m²). Right ventricular (RV) volumes were significantly larger in males compared to females for absolute and indexed values and were smaller with advancing age. RV ejection fraction was higher with increasing age in females only. Left atrial (LA) maximal volume and stroke volume were significantly larger in males compared to females for absolute values but not for indexed values. LA ejection fraction was similar for both sexes. Right atrial (RA) maximal volume was significantly larger in males for both absolute and indexed values, while RA ejection fraction was significantly higher in females. Conclusions: We describe age- and sex-specific reference ranges for the left ventricle, right ventricle and atria in the largest validated normal Caucasian population. [ABSTRACT FROM AUTHOR]
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- 2017
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13. The global cardiovascular magnetic resonance registry (GCMR) of the society for cardiovascular magnetic resonance (SCMR): its goals, rationale, data infrastructure, and current developments.
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Kwong, Raymond Y., Petersen, Steffen E., Schulz-Menger, Jeanette, Arai, Andrew E., Bingham, Scott E., Yucheng Chen, Yuna L. Choi, Cury, Ricardo C., Ferreira, Vanessa M., Flamm, Scott D., Steel, Kevin, Bandettini, W. Patricia, Martin, Edward T., Nallamshetty, Leelakrishna, Neubauer, Stefan, Raman, Subha V., Schelbert, Erik B., Valeti, Uma S., Jie Jane Cao, and Reichek, Nathaniel
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ARRHYTHMIA diagnosis , *CHEST pain diagnosis , *CARDIOMYOPATHIES , *CARDIOVASCULAR disease diagnosis , *DATABASE management , *DECISION making , *ELECTROPHYSIOLOGY , *MAGNETIC resonance imaging , *MANAGEMENT , *SURVEYS , *ORGANIZATIONAL goals , *CONTRAST media , *DIAGNOSIS - Abstract
Background: With multifaceted imaging capabilities, cardiovascular magnetic resonance (CMR) is playing a progressively increasing role in the management of various cardiac conditions. A global registry that harmonizes data from international centers, with participation policies that aim to be open and inclusive of all CMR programs, can support future evidence-based growth in CMR. Methods: The Global CMR Registry (GCMR) was established in 2013 under the auspices of the Society for Cardiovascular Magnetic Resonance (SCMR). The GCMR team has developed a web-based data infrastructure, data use policy and participation agreement, data-harmonizing methods, and site-training tools based on results from an international survey of CMR programs. Results: At present, 17 CMR programs have established a legal agreement to participate in GCMR, amongst them 10 have contributed CMR data, totaling 62,456 studies. There is currently a predominance of CMR centers with more than 10 years of experience (65%), and the majority are located in the United States (63%). The most common clinical indications for CMR have included assessment of cardiomyopathy (21%), myocardial viability (16%), stress CMR perfusion for chest pain syndromes (16%), and evaluation of etiology of arrhythmias or planning of electrophysiological studies (15%) with assessment of cardiomyopathy representing the most rapidly growing indication in the past decade. Most CMR studies involved the use of gadolinium-based contrast media (95%). Conclusions: We present the goals, mission and vision, infrastructure, preliminary results, and challenges of the GCMR. Trial registration: Identification number on ClinicalTrials.gov: NCT02806193. Registered 17 June 2016. [ABSTRACT FROM AUTHOR]
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- 2017
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14. Cost-minimization analysis of three decision strategies for cardiac revascularization: results of the "suspected CAD" cohort of the european cardiovascular magnetic resonance registry.
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Moschetti, Karine, Petersen, Steffen E., Pilz, Guenter, Kwong, Raymond Y., Wasserfallen, Jean-Blaise, Lombardi, Massimo, Korosoglou, Grigorios, Van Rossum, Albert C., Bruder, Oliver, Mahrholdt, Heiko, and Schwitter, Juerg
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DIAGNOSIS , *CORONARY disease , *CORONARY heart disease treatment , *ANGINA pectoris , *CHEST pain , *CHI-squared test , *DATABASES , *MEDICAL information storage & retrieval systems , *MAGNETIC resonance imaging , *RESEARCH funding , *DECISION making in clinical medicine , *COST analysis , *REVASCULARIZATION (Surgery) , *DESCRIPTIVE statistics , *CORONARY angiography , *ONE-way analysis of variance - Abstract
Background: Coronary artery disease (CAD) continues to be one of the top public health burden. Perfusion cardiovascular magnetic resonance (CMR) is generally accepted to detect CAD, while data on its cost effectiveness are scarce. Therefore, the goal of the study was to compare the costs of a CMR-guided strategy vs two invasive strategies in a large CMR registry. Methods: In 3'647 patients with suspected CAD of the EuroCMR-registry (59 centers/18 countries) costs were calculated for diagnostic examinations (CMR, X-ray coronary angiography (CXA) with/without FFR), revascularizations, and complications during a 1-year follow-up. Patients with ischemia-positive CMR underwent an invasive CXA and revascularization at the discretion of the treating physician (=CMR + CXA-strategy). In the hypothetical invasive arm, costs were calculated for an initial CXA and a FFR in vessels with ≥50 % stenoses (=CXA + FFR-strategy) and the same proportion of revascularizations and complications were applied as in the CMR + CXA-strategy. In the CXA-only strategy, costs included those for CXA and for revascularizations of all ≥50 % stenoses. To calculate the proportion of patients with ≥50 % stenoses, the stenosis-FFR relationship from the literature was used. Costs of the three strategies were determined based on a third payer perspective in 4 healthcare systems. Results: Revascularizations were performed in 6.2 %, 4.5 %, and 12.9 % of all patients, patients with atypical chest pain (n =1'786), and typical angina (n = 582), respectively; whereas complications (=all-cause death and non-fatal infarction) occurred in 1.3 %, 1.1 %, and 1.5 %, respectively. The CMR + CXA-strategy reduced costs by 14 %, 34 %, 27 %, and 24 % in the German, UK, Swiss, and US context, respectively, when compared to the CXA + FFR-strategy; and by 59 %, 52 %, 61 % and 71 %, respectively, versus the CXA-only strategy. In patients with typical angina, cost savings by CMR + CXA vs CXA + FFR were minimal in the German (2.3 %), intermediate in the US and Swiss (11.6 % and 12.8 %, respectively), and remained substantial in the UK (18.9 %) systems. Sensitivity analyses proved the robustness of results. Conclusions: A CMR + CXA-strategy for patients with suspected CAD provides substantial cost reduction compared to a hypothetical CXA + FFR-strategy in patients with low to intermediate disease prevalence. However, in the subgroup of patients with typical angina, cost savings were only minimal to moderate. [ABSTRACT FROM AUTHOR]
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- 2016
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15. UK Biobank's cardiovascular magnetic resonance protocol.
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Petersen, Steffen E., Matthews, Paul M., Francis, Jane M., Robson, Matthew D., Zemrak, Filip, Boubertakh, Redha, Young, Alistair A., Hudson, Sarah, Weale, Peter, Garratt, Steve, Collins, Rory, Piechnik, Stefan, and Neubauer, Stefan
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CARDIOVASCULAR disease diagnosis , *EXPERIMENTAL design , *LONGITUDINAL method , *MAGNETIC resonance imaging , *RESEARCH methodology , *DESCRIPTIVE statistics - Abstract
Background: UK Biobank's ambitious aim is to perform cardiovascular magnetic resonance (CMR) in 100,000 people previously recruited into this prospective cohort study of half a million 40-69 year-olds. Methods/design: We describe the CMR protocol applied in UK Biobank's pilot phase, which will be extended into the main phase with three centres using the same equipment and protocols. The CMR protocol includes white blood CMR (sagittal anatomy, coronary and transverse anatomy), cine CMR (long axis cines, short axis cines of the ventricles, coronal LVOT cine), strain CMR (tagging), flow CMR (aortic valve flow) and parametric CMR (native T1 map). Discussion: This report will serve as a reference to researchers intending to use the UK Biobank resource or to replicate the UK Biobank cardiovascular magnetic resonance protocol in different settings. [ABSTRACT FROM AUTHOR]
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- 2016
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16. Cardiovascular magnetic resonance imaging of myocardial oedema following acute myocardial infarction: Is whole heart coverage necessary?
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Hamshere, Stephen, Jones, Daniel A., Pellaton, Cyril, Longchamp, Danielle, Burchell, Tom, Mohiddin, Saidi, Moon, James C., Kastrup, Jens, Locca, Didier, Petersen, Steffen E., Westwood, Mark, and Mathur, Anthony
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CONFIDENCE intervals ,STATISTICAL correlation ,EDEMA ,FISHER exact test ,MAGNETIC resonance imaging ,MYOCARDIAL infarction ,RESEARCH evaluation ,STATISTICAL hypothesis testing ,INTER-observer reliability ,DATA analysis software ,DESCRIPTIVE statistics ,CORONARY angiography ,INTRACLASS correlation - Abstract
Background: AAR measurement is useful when assessing the efficacy of reperfusion therapy and novel cardioprotective agents after myocardial infarction. Multi-slice (Typically 10-12) T2-STIR has been used widely for its measurement, typically with a short axis stack (SAX) covering the entire left ventricle, which can result in long acquisition times and multiple breath holds. This study sought to compare 3-slice T2-short-tau inversion recovery (T2- STIR) technique against conventional multi-slice T2-STIR technique for the assessment of area at risk (AAR). Methods: CMR imaging was performed on 167 patients after successful primary percutaneous coronary intervention. 82 patients underwent a novel 3-slice SAX protocol and 85 patients underwent standard 10-slice SAX protocol. AAR was obtained by manual endocardial and epicardial contour mapping followed by a semi-automated selection of normal myocardium; the volume was expressed as mass (%) by two independent observers. Results: 85 patients underwent both 10-slice and 3-slice imaging assessment showing a significant and strong correlation (intraclass correlation coefficient = 0.92;p < 0.0001) and a low Bland-Altman limit (mean difference -0.03 ± 3.21 %, 95 % limit of agreement,- 6.3 to 6.3) between the 2 analysis techniques. A further 82 patients underwent 3-slice imaging alone, both the 3-slice and the 10-slice techniques showed statistically significant correlations with angiographic risk scores (3-slice to BARI r = 0.36, 3-slice to APPROACH r = 0.42, 10-slice to BARI r = 0.27, 10-slice to APPROACH r= 0.46). There was low inter-observer variability demonstrated in the 3-slice technique, which was comparable to the 10-slice method (z = 1.035, p = 0.15). Acquisition and analysis times were quicker in the 3-slice compared to the 10-slice method (3-slice median time: 100 seconds (IQR: 65-171 s) vs (10-slice time: 355 seconds (IQR: 275-603 s); p < 0.0001. Conclusions: AAR measured using 3-slice T2-STIR technique correlates well with standard 10-slice techniques, with no significant bias demonstrated in assessing the AAR. The 3-slice technique requires less time to perform and analyse and is therefore advantageous for both patients and clinicians. [ABSTRACT FROM AUTHOR]
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- 2016
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17. Fractal frontiers in cardiovascular magnetic resonance: towards clinical implementation.
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Captur, Gabriella, Karperien, Audrey L., Chunming Li, Zemrak, Filip, Tobon-Gomez, Catalina, Xuexin Gao, Bluemke, David A., Elliott, Perry M., Petersen, Steffen E., and Moon, James C.
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CARDIOVASCULAR disease diagnosis ,COMPUTER software ,DIGITAL diagnostic imaging ,DIGITAL image processing ,MAGNETIC resonance imaging ,MATHEMATICS - Abstract
Many of the structures and parameters that are detected, measured and reported in cardiovascular magnetic resonance (CMR) have at least some properties that are fractal, meaning complex and self-similar at different scales. To date however, there has been little use of fractal geometry in CMR; by comparison, many more applications of fractal analysis have been published in MR imaging of the brain. This review explains the fundamental principles of fractal geometry, places the fractal dimension into a meaningful context within the realms of Euclidean and topological space, and defines its role in digital image processing. It summarises the basic mathematics, highlights strengths and potential limitations of its application to biomedical imaging, shows key current examples and suggests a simple route for its successful clinical implementation by the CMR community. By simplifying some of the more abstract concepts of deterministic fractals, this review invites CMR scientists (clinicians, technologists, physicists) to experiment with fractal analysis as a means of developing the next generation of intelligent quantitative cardiac imaging tools. [ABSTRACT FROM AUTHOR]
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- 2015
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18. Extracellular volume quantification in isolated hypertension - changes at the detectable limits?
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Treibel, Thomas A., Zemrak, Filip, Sado, Daniel M., Banypersad, Sanjay M., White, Steven K., Maestrini, Viviana, Barison, Andrea, Patel, Vimal, Herrey, Anna S., Davies, Ceri, Caulfield, Mark J., Petersen, Steffen E., and Moon, James C.
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ECHOCARDIOGRAPHY ,EXTRACELLULAR fluid ,HYPERTENSION ,MAGNETIC resonance imaging ,RESEARCH funding ,T-test (Statistics) ,CONTROL groups ,DATA analysis software ,DESCRIPTIVE statistics ,MANN Whitney U Test - Abstract
Background: Diffuse myocardial fibrosis (DMF) is important in cardiovascular disease, however until recently could only be assessed by invasive biopsy. We hypothesised that DMF measured by T1 mapping is elevated in isolated systemic hypertension. Methods: In a study of well-controlled hypertensive patients from a specialist tertiary centre, 46 hypertensive patients (median age 56, range 21 to 78, 52 % male) and 50 healthy volunteers (median age 45, range 28 to 69, 52 % male) underwent clinical CMR at 1.5 T with T1 mapping (ShMOLLI) using the equilibrium contrast technique for extracellular volume (ECV) quantification. Patients underwent 24-hours Automated Blood Pressure Monitoring (ABPM), echocardiographic assessment of diastolic function, aortic stiffness assessment and measurement of NT-pro-BNP and collagen biomarkers. Results: Late gadolinium enhancement (LGE) revealed significant unexpected underlying pathology in 6 out of 46 patients (13 %; myocardial infarction n = 3; hypertrophic cardiomyopathy (HCM) n = 3); these were subsequently excluded. Limited, non-ischaemic LGE patterns were seen in 11 out of the remaining 40 (28 %) patients. Hypertensives on therapy (mean 2.2 agents) had a mean ABPM of 152/88 mmHg, but only 35 % (14/40) had left ventricular hypertrophy (LVH; LV mass male > 90 g/m²; female > 78 g/m²). Native myocardial T1 was similar in hypertensives and controls (955 ± 30 ms versus 965 ± 38 ms, p = 0.16). The difference in ECV did not reach significance (0.26 ± 0.02 versus 0.27 ± 0.03, p = 0.06). In the subset with LVH, the ECV was significantly higher (0.28 ± 0.03 versus 0.26 ± 0.02, p < 0.001). Conclusion: In well-controlled hypertensive patients, conventional CMR discovered significant underlying diseases (chronic infarction, HCM) not detected by echocardiography previously or even during this study. T1 mapping revealed increased diffuse myocardial fibrosis, but the increases were small and only occurred with LVH. [ABSTRACT FROM AUTHOR]
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- 2015
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19. Comparative cost-effectiveness analyses of cardiovascular magnetic resonance and coronary angiography combined with fractional flow reserve for the diagnosis of coronary artery disease.
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Moschetti, Karine, Favre, David, Pinget, Christophe, Pilz, Guenter, Petersen, Steffen E., Wagner, Anja, Schwitter, Juerg J., and Wasserfallen, Jean-Blaise
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CORONARY disease ,DIAGNOSIS ,ALGORITHMS ,COMPARATIVE studies ,COST effectiveness ,MAGNETIC resonance imaging ,MATHEMATICS ,RESEARCH funding ,DATA analysis software ,STATISTICAL models ,DESCRIPTIVE statistics ,CORONARY angiography - Abstract
Background According to recent guidelines, patients with coronary artery disease (CAD) should undergo revascularization if significant myocardial ischemia is present. Both, cardiovascular magnetic resonance (CMR) and fractional flow reserve (FFR) allow for a reliable ischemia assessment and in combination with anatomical information provided by invasive coronary angiography (CXA), such a work-up sets the basis for a decision to revascularize or not. The cost-effectiveness ratio of these two strategies is compared. Methods Strategy 1) CMR to assess ischemia followed by CXA in ischemia-positive patients (CMR + CXA), Strategy 2) CXA followed by FFR in angiographically positive stenoses (CXA + FFR). The costs, evaluated from the third party payer perspective in Switzerland, Germany, the United Kingdom (UK), and the United States (US), included public prices of the different outpatient procedures and costs induced by procedural complications and by diagnostic errors. The effectiveness criterion was the correct identification of hemodynamically significant coronary lesion(s) (= significant CAD) complemented by full anatomical information. Test performances were derived from the published literature. Cost-effectiveness ratios for both strategies were compared for hypothetical cohorts with different pretest likelihood of significant CAD. Results CMR + CXA and CXA + FFR were equally cost-effective at a pretest likelihood of CAD of 62% in Switzerland, 65% in Germany, 83% in the UK, and 82% in the US with costs of CHF 5'794, € '517, £ 2'680, and $ 2'179 per patient correctly diagnosed. Below these thresholds, CMR + CXA showed lower costs per patient correctly diagnosed than CXA + FFR. Conclusions The CMR + CXA strategy is more cost-effective than CXA + FFR below a CAD prevalence of 62%, 65%, 83%, and 82% for the Swiss, the German, the UK, and the US health care systems, respectively. These findings may help to optimize resource utilization in the diagnosis of CAD. [ABSTRACT FROM AUTHOR]
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- 2014
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20. Imaging in population science: cardiovascular magnetic resonance in 100,000 participants of UK Biobank - rationale, challenges and approaches.
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Petersen, Steffen E., Matthews, Paul M., Bamberg, Fabian, Bluemke, David A., Francis, Jane M., Friedrich, Matthias G., Leeson, Paul, Nagel, Eike, Plein, Sven, Rademakers, Frank E., Young, Alistair A., Garratt, Steve, Peakman, Tim, Sellors, Jonathan, Collins, Rory, and Neubauer, Stefan
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RESEARCH methodology , *MEDICAL care costs , *QUALITY control , *PHENOTYPES , *MAGNETIC resonance angiography - Abstract
UK Biobank is a prospective cohort study with 500,000 participants aged 40 to 69. Recently an enhanced imaging study received funding. Cardiovascular magnetic resonance (CMR) will be part of a multi-organ, multi-modality imaging visit in 3-4 dedicated UK Biobank imaging centres that will acquire and store imaging data from 100,000 participants (subject to successful piloting). In each of UK Biobank's dedicated bespoke imaging centres, it is proposed that 15-20 participants will undergo a 2 to 3 hour visit per day, seven days a week over a period of 5-6 years. The imaging modalities will include brain MRI at 3 Tesla, CMR and abdominal MRI at 1.5 Tesla, carotid ultrasound and DEXA scans using carefully selected protocols. We reviewed the rationale, challenges and proposed approaches for concise phenotyping using CMR on such a large scale. Here, we discuss the benefits of this imaging study and review existing and planned population based cardiovascular imaging in prospective cohort studies. We will evaluate the CMR protocol, feasibility, process optimisation and costs. Procedures for incidental findings, quality control and data processing and analysis are also presented. As is the case for all other data in the UK Biobank resource, this database of images and related information will be made available through UK Biobank's Access Procedures to researchers (irrespective of their country of origin and whether they are academic or commercial) for health-related research that is in the public interest. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
- View/download PDF
21. Global and regional left ventricular myocardial deformation measures by magnetic resonance feature tracking in healthy volunteers: comparison with tagging and relevance of gender.
- Author
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Augustine, Daniel, Lewandowski, Adam J., Lazdam, Merzaka, Rai, Aitzaz, Francis, Jane, Myerson, Saul, Noble, Alison, Becher, Harald, Neubauer, Stefan, Petersen, Steffen E., and Leeson, Paul
- Subjects
MAGNETIC resonance imaging evaluation ,ANALYSIS of variance ,MYOCARDIUM ,PROBABILITY theory ,RESEARCH evaluation ,RESEARCH funding ,STATISTICS ,T-test (Statistics) ,DATA analysis ,INTER-observer reliability ,REPEATED measures design ,DATA analysis software ,DESCRIPTIVE statistics - Abstract
Background: Feature Tracking software offers measurements of myocardial strain, velocities and displacement from cine cardiovascular magnetic resonance (CMR) images. We used it to record deformation parameters in healthy adults and compared values to those obtained by tagging. Methods: We used TomTec 2D Cardiac Performance Analysis software to derive global, regional and segmental myocardial deformation parameters in 145 healthy volunteers who had steady state free precession (SSFP) cine left ventricular short (basal, mid and apical levels) and long axis views (horizontal long axis, vertical long axis and left ventricular out flow tract) obtained on a 1.5 T Siemens Sonata scanner. 20 subjects also had tagged acquisitions and we compared global and regional deformation values obtained from these with those from Feature Tracking. Results: For globally averaged measurements of strain, only those measured circumferentially in short axis slices showed reasonably good levels of agreement between FT and tagging (limits of agreement ?0.06 to 0.04). Longitudinal strain showed wide limits of agreement (-0.16 to 0.03) with evidence of overestimation of strain by FT relative to tagging as the mean of both measures increased. Radial strain was systematically overestimated by FT relative to tagging with very wide limits of agreement extending to as much as 100% of the mean value (-0.01 to 0.23). Reproducibility showed similar relative trends with acceptable global inter-observer variability for circumferential measures (coefficient of variation 4.9%) but poor reproducibility in the radial direction (coefficient of variation 32.3%). Ranges for deformation parameters varied between basal, mid and apical LV levels with higher levels at base compared to apex, and between genders by both FT and tagging. Conclusions: FT measurements of circumferential but not longitudinally or radially directed global strain showed reasonable agreement with tagging and acceptable inter-observer reproducibility. We record provisional ranges of FT deformation parameters at global, regional and segmental levels. They show evidence of variation with gender and myocardial region in the volunteers studied, but have yet to be compared with tagging measurements at the segmental level. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
- View/download PDF
22. Contrast-enhanced CMR in patients after percutaneous closure of the left atrial appendage: A pilot study.
- Author
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Mohrs, Oliver K., Wunderlich, Nina, Petersen, Steffen E., Pottmeyer, Anselm, and Kauczor, Hans-Ulrich
- Subjects
ARTERIAL occlusions ,ARTERIAL diseases ,BLOOD circulation ,CATHETERS ,FEASIBILITY studies - Abstract
Background: To evaluate the feasibility and value of first-pass contrast-enhanced dynamic and post-contrast 3D CMR in patients after transcatheter occlusion of left atrial appendage (LAA) to identify incorrect placement and persistent leaks. Methods: 7 patients with different occluder systems (n = 4 PLAATO; n = 2 Watchman; n = 1 ACP) underwent 2 contrast-enhanced (Gd-DOTA) CMR sequences (2D TrueFISP first-pass perfusion and 3D-TurboFLASH) to assess localization, artifact size and potential leaks of the devices. Perfusion CMR was analyzed visually and semiquantitatively to identify potential leaks. Results: All occluders were positioned within the LAA. The ACP occluder presented the most extensive artifact size. Visual assessment revealed a residual perfusion of the LAA apex in 4 cases using first-pass perfusion and 3DTurboFLASH indicating a suboptimal LAA occlusion. By assessing signal-to-time-curves the cases with a visually detected leak showed a 9-fold higher signal-peak in the LAA apex (567 ± 120% increase from baseline signal) than those without a leak (61 ± 22%; p < 0.03). In contrast, the signal increase in LAA proximal to the occluder showed no difference (leak 481 ± 201% vs. no leak 478 ± 125%; p = 0.48). Conclusion: This CMR pilot study provides valuable non-invasive information in patients after transcatheter occlusion of the LAA to identify correct placement and potential leaks. We recommend incorporating CMR in future clinical studies to evaluate new device types. [ABSTRACT FROM AUTHOR]
- Published
- 2011
- Full Text
- View/download PDF
23. Determinants of left ventricular mass in obesity; a cardiovascular magnetic resonance study.
- Author
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Rider, Oliver J., Francis, Jane M., Ali, Mohammed K., Byrne, James, Clarke, Kieran, Neubauer, Stefan, and Petersen, Steffen E.
- Subjects
LEFT heart ventricle ,OBESITY ,MAGNETIC resonance imaging ,CARDIOVASCULAR diseases risk factors ,SERUM ,BLOOD pressure ,INSULIN ,MEDICAL imaging systems ,CARDIAC imaging - Abstract
Background: Obesity is linked to increased left ventricular mass, an independent predictor of mortality. As a result of this, understanding the determinants of left ventricular mass in the setting of obesity has both therapeutic and prognostic implications. Using cardiovascular magnetic resonance our goal was to elucidate the main predictors of left ventricular mass in severely obese subjects free of additional cardiovascular risk factors. Methods: 38 obese (BMI 37.8 ± 6.9 kg/m²) and 16 normal weight controls subjects, (BMI 21.7 ± 1.8 kg/m²), all without cardiovascular risk factors, underwent cardiovascular magnetic resonance imaging to assess left ventricular mass, left ventricular volumes and visceral fat mass. Left ventricular mass was then compared to serum and anthropometric markers of obesity linked to left ventricular mass, i.e. height, age, blood pressure, total fat mass, visceral fat mass, lean mass, serum leptin and fasting insulin level. Results: As expected, obesity was associated with significantly increased left ventricular mass (126 ± 27 vs 90 ± 20 g; p < 0.001). Stepwise multiple regression analysis showed that over 75% of the cross sectional variation in left ventricular mass can be explained by lean body mass (β = 0.51, p < 0.001), LV stroke volume (β = 0.31 p = 0.001) and abdominal visceral fat mass (β = 0.20, p = 0.02), all of which showed highly significant independent associations with left ventricular mass (overall R² = 0.77). Conclusion: The left ventricular hypertrophic response to obesity in the absence of additional cardiovascular risk factors is mainly attributable to increases in lean body mass, LV stroke volume and visceral fat mass. In view of the well documented link between obesity, left ventricular hypertrophy and mortality, these findings have potentially important prognostic and therapeutic implications for primary and secondary prevention. [ABSTRACT FROM AUTHOR]
- Published
- 2009
- Full Text
- View/download PDF
24. Simplifying cardiovascular magnetic resonance pulse sequence terminology.
- Author
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Friedrich, Matthias G., Bucciarelli-Ducci, Chiara, White, James A., Plein, Sven, Moon, James C., Almeida, Ana G., Kramer, Christopher M., Neubauer, Stefan, Pennell, Dudley J., Petersen, Steffen E., Kwong, Raymond Y., Ferrari, Victor A., Schulz-Menger, Jeanette, Sakuma, Hajime, Schelbert, Erik B., Larose, ric, Eitel, Ingo, Carbone, Iacopo, Taylor, Andrew J., and Young, Alistair
- Subjects
CARDIOVASCULAR disease diagnosis ,COMMUNICATION ,MAGNETIC resonance imaging ,MEDICAL care ,PATIENTS ,PHYSICIANS - Abstract
We propose a set of simplified terms to describe applied Cardiovascular Magnetic Resonance (CMR) pulse sequence techniques in clinical reports, scientific articles and societal guidelines or recommendations. Rather than using various technical details in clinical reports, the description of the technical approach should be based on the purpose of the pulse sequence. In scientific papers or other technical work, this should be followed by a more detailed description of the pulse sequence and settings. The use of a unified set of widely understood terms would facilitate the communication between referring physicians and CMR readers by increasing the clarity of CMR reports and thus improve overall patient care. Applied in research articles, its use would facilitate non-expert readers? understanding of the methodology used and its clinical meaning. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
25. Visualisation of aortic flow disturbance in Marfan syndrome by 4D phase-contrast CMR.
- Author
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Pitcher, Alex, Cassar, Tom E., Suttie, Joseph, Francis, Jane M., Leeson, Paul, Blair, Edward, Wordsworth, B. Paul, Forfar, J. Colin, Myerson, Saul G., Markl, Michael, Neubauer, Stefan, and Petersen, Steffen E.
- Subjects
MARFAN syndrome - Abstract
The article presents an abstract on a paper titled "Visualisation of Aortic Flow Disturbance in Marfan Syndrome by 4D Phase-Contrast CMR," presented at the 2011 Society for Cardiovascular Magnetic Resonance (CMR)/Euro CMR Joint Scientific Sessions held in France.
- Published
- 2011
- Full Text
- View/download PDF
26. Stress myocardial perfusion cardiac magnetic resonance imaging vs. coronary CT angiography in the diagnostic work-up of patients with stable chest pain: comparative effectiveness and costs.
- Author
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Genders, Tessa S., Petersen, Steffen E., Pugliese, Francesca, Ghosh Dastidar, Amardeep, Fleischmann, Kirsten E., Nieman, Koen, and Hunink, Myriam
- Subjects
- *
DIAGNOSIS , *BLOOD vessels , *CHEST pain , *COMPUTED tomography , *CONFERENCES & conventions , *CORONARY disease , *COST effectiveness , *MAGNETIC resonance imaging , *QUALITY-adjusted life years , *CORONARY angiography , *ECONOMICS - Abstract
An abstract of the article "Stress myocardial perfusion cardiac magnetic resonance imaging vs. coronary CT angiography in the diagnostic work-up of patients with stable chest pain: comparative effectiveness and costs," by Tessa S. Genders and colleagues is presented.
- Published
- 2013
- Full Text
- View/download PDF
27. Diffuse interstitial fibrosis in well-controlled hypertension.
- Author
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Treibe, Thomas A., Zemrak, Filip, White, Steven K., Sado, Daniel, Banypersad, Sanjay M., Maestrini, Viviana, Caulfield, Mark, Petersen, Steffen E., and Moon, James
- Subjects
FIBROSIS ,CARDIOVASCULAR disease diagnosis ,CONFERENCES & conventions ,HYPERTENSION ,MAGNETIC resonance imaging ,MYOCARDIUM ,DIAGNOSIS - Abstract
An abstract of the article "Diffuse interstitial fibrosis in well-controlled hypertension," by Thomas A. Treibe, Filip Zemrak, Steven K. White, Daniel Sado, Sanjay M. Banypersad, Viviana Maestrini, Mark Caufield, Steffen E. Petersen and James Moon is presented.
- Published
- 2013
- Full Text
- View/download PDF
28. European Cardiovascular Magnetic Resonance (EuroCMR) registry - multi national tesults from 57 centers in 15 countries.
- Author
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Wagner, Anja, Bruder, Oliver, Lombardi, Massimo, Schwitter, Juerg, van Rossum, Albert C., Pilz, Guenter, Nothnagel, Detlev, Petersen, Steffen E., Nagel, Eike, Prasad, Sanjay K., Frank, Herbert, Dill, Thorsten, Schneider, Steffen, and Mahrholdt, Heiko
- Subjects
CARDIOVASCULAR disease diagnosis ,CONFERENCES & conventions ,MAGNETIC resonance imaging - Abstract
An abstract of the article "European Cardiovascular Magnetic Resonance (EuroCMR) registry - multi national results from 57 centers in 15 countries," by Anja Wagner and colleagues is presented.
- Published
- 2013
- Full Text
- View/download PDF
29. Interstitial expansion in pressure overload left ventricular hypertrophy.
- Author
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Treibel, Thomas A., White, Steven K., Sado, Daniel, Zemrak, Filip, Banypersad, Sanjay M., Flett, Andrew, Caulfield, Mark, Herrey, Anna S., Petersen, Steffen E., and Moon, James
- Subjects
BLOOD pressure ,CONFERENCES & conventions ,EXTRACELLULAR fluid ,HEART ventricles ,LEFT ventricular hypertrophy - Abstract
An abstract of the article "Interstitial expansion in pressure overload left ventricular hypertrophy," by Thomas A. Treibel and colleagues is presented.
- Published
- 2013
- Full Text
- View/download PDF
30. Cardiac magnetic resonance myocardial feature tracking: feasibility for use in left ventricular non-compaction.
- Author
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Stone, Ian S., Boubertakh, Redha, Stephenson, Edward J., Zemrak, Filip, Weerackody, Roshan, Sekhri, Neha, Westwood, Mark A., Davies, Ceri, Mohiddin, Saidi A., and Petersen, Steffen E.
- Subjects
MYOCARDIUM physiology ,CARDIOMYOPATHIES ,CONFERENCES & conventions ,MAGNETIC resonance imaging ,DIAGNOSIS - Abstract
An abstract of the article "Cardiac magnetic resonance myocardial feature tracking: feasibility for use in left ventricular non-compaction," by Ian S. Stone, Redha Boubertakh, Edward J. Stephenson, and colleagues is presented.
- Published
- 2013
- Full Text
- View/download PDF
31. Cardiac magnetic resonance myocardial featuretracking: the effect of treatment in patients with adult-onset growth hormone deficiency and acromegaly.
- Author
-
Javaid, Mahvesh R., Stone, Ian S., Grossman, Ashley B., Korbonits, Marta, Thomas, Julia D., Petersen, Steffen E., and Davies, Ceri
- Subjects
ACROMEGALY ,AGE factors in disease ,CONFERENCES & conventions ,MAGNETIC resonance imaging ,HUMAN growth hormone - Abstract
An abstract of the article "Cardiac magnetic resonance myocardial featuretracking: the effect of treatment in patients with adult-onset growth hormone deficiency and acromegaly," by Mahvesh R. Javaid and colleagues is presented.
- Published
- 2013
- Full Text
- View/download PDF
32. CMR right ventricular strain assessment using feature tracking cine images: agreement with echocardiography.
- Author
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Augustine, Daniel, Suttie, Joseph J., Cox, Peter, Lewandowski, Adam J., Holloway, Cameron, Petersen, Steffen E., Myerson, Saul, Neubauer, Stefan, and Leeson, Paul
- Subjects
ECHOCARDIOGRAPHY - Abstract
An abstract of the conference paper "CMR right ventricular strain assessment using feature tracking cine images: Agreement with echocardiography," by Daniel Augustine and colleagues is presented.
- Published
- 2012
- Full Text
- View/download PDF
33. Magnetic resonance imaging pre and post pulmonary vein isolation for atrial fibrillation: diagnostic accuracy to detect and characterize ablation lesions.
- Author
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Jones, Daniel A., Hunter, Ross J., Boubertakh, Redha, Malcolme-Lawes, Louisa, Kanagaratnam, Prapa, Peters, Nicholas S., Juli, Christoph, Baker, Victoria, Earley, Mark, Sporton, Simon, Davies, Ceri, Westwood, Mark, Schilling, Richard J., and Petersen, Steffen E.
- Subjects
MAGNETIC resonance imaging - Abstract
An abstract of the conference paper "Magnetic resonance imaging pre and post pulmonary vein isolation for atrial fibrillation: Diagnostic accuracy to detect and characterize ablation lesions," by Daniel A. Jones and colleagues is presented.
- Published
- 2012
- Full Text
- View/download PDF
34. Gender specific differences in left ventricular remodelling in obesity may explain differences in obesity related mortality.
- Author
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Rider, Oliver J., Lewandowski, Adam J., Nethononda, Richard, Petersen, Steffen E., Pitcher, Alex, Holloway, Cameron, Banerjee, Rajarshi, Byrne, James P., Leeson, Paul, and Neubauer, Stefan
- Subjects
LEFT heart ventricle ,OBESITY - Abstract
An abstract of the conference paper "Gender specific differences in left ventricular remodelling in obesity may explain differences in obesity related mortality," by Alex Pitcher, and colleagues is presented.
- Published
- 2012
- Full Text
- View/download PDF
35. The natural time course of myocardial oedema in the 12 months post ST-elevation MI in patients treated with primary angioplasty.
- Author
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Burchell, Thomas R., Westwood, Mark, Petersen, Steffen E., Mohiddin, Saidi A., and Davies, Ceri
- Subjects
EDEMA ,ANGIOPLASTY ,PATIENTS - Abstract
An abstract of the conference paper "The natural time course of myocardial oedema in the 12 months post ST-elevation MI in patients treated with primary angioplasty," by Thomas R. Burchell and colleagues is presented.
- Published
- 2012
- Full Text
- View/download PDF
36. Cardiovascular changes in patients with acromegaly assessed by CMR.
- Author
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Zemrak, Filip, Thomas, Julia, Dattani, Abhishek, Burchell, Thomas R., Petersen, Steffen E., Grossman, Ashley, Korbonits3, Marta, and Davies, Ceri
- Subjects
CARDIOVASCULAR system ,ACROMEGALY ,PATIENTS - Abstract
An abstract of the conference paper "Cardiovascular changes in patients with acromegaly assessed by CMR," by Filip Zemrak and colleagues is presented.
- Published
- 2012
- Full Text
- View/download PDF
37. Does change in heart rate and blood pressure during adenosine stress perfusion cardiovascular magnetic resonance (A-CMRP) imaging predict perfusion defects?
- Author
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Rathod, Krishnaraj S., Davies, Ceri, Petersen, Steffen E., Westwood, Mark, and Sekhri, Neha
- Subjects
HEART beat ,MAGNETIC resonance - Abstract
An abstract of the conference paper "Does change in heart rate and blood pressure during adenosine stress perfusion cardiovascular magnetic resonance (A-CMRP) imaging predict perfusion defects?," by Ceri Davies and colleagues is presented.
- Published
- 2012
- Full Text
- View/download PDF
38. Aortic dissection: visualisation of aortic blood flow and quantification of wall shear stress using time-resolved, 3D phase-contrast MRI.
- Author
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Pitcher, Alex, Cassar, Tom E., Leeson, Paul, Francis, Jane M., Blair, Edward, Wordsworth, Paul B., Forfar, J Colin, Petersen, Steffen E., Markl, Michael, and Neubauer, Stefan
- Subjects
AORTIC dissection - Abstract
An abstract of the paper "Aortic Dissection: Visualisation of Aortic Blood Flow and Quantification of Wall Shear Stress Using Time-resolved, 3D Phase-contrast MRI," by Alex Pitcher and colleagues, from the 2011 SCMR/Euro CMR Joint Scientific Sessions, held in Nice, France, from February 3-6, 2011, is presented.
- Published
- 2011
- Full Text
- View/download PDF
39. Comparing analysis methods for quantification of myocardial oedema in patients following reperfused ST-elevation MI.
- Author
-
Burchell, Tom, Flett, Andrew S., Petersen, Steffen E., Davies, L. Ceri, Mohiddin, Saidi A., Mathur, Anthony, and Westwood, Mark A.
- Subjects
EDEMA - Abstract
An abstract of the paper "Comparing Analysis Methods for Quantification of Myocardial Oedema in Patients Following Reperfused ST-Elevation MI," by Tom Burchell and colleagues is presented.
- Published
- 2011
- Full Text
- View/download PDF
40. Simplifying cardiovascular magnetic resonance pulse sequence terminology
- Author
-
Friedrich, Matthias G, Bucciarelli-Ducci, Chiara, White, James A, Plein, Sven, Moon, James C, Almeida, Ana G, Kramer, Christopher M, Neubauer, Stefan, Pennell, Dudley J, Petersen, Steffen E, Kwong, Raymond Y, Ferrari, Victor A, Schulz-Menger, Jeanette, Sakuma, Hajime, Schelbert, Erik B, Larose, Éric, Eitel, Ingo, Carbone, Iacopo, Taylor, Andrew J, Young, Alistair, de Roos, Albert, and Nagel, Eike
- Abstract
We propose a set of simplified terms to describe applied Cardiovascular Magnetic Resonance (CMR) pulse sequence techniques in clinical reports, scientific articles and societal guidelines or recommendations. Rather than using various technical details in clinical reports, the description of the technical approach should be based on the purpose of the pulse sequence. In scientific papers or other technical work, this should be followed by a more detailed description of the pulse sequence and settings. The use of a unified set of widely understood terms would facilitate the communication between referring physicians and CMR readers by increasing the clarity of CMR reports and thus improve overall patient care. Applied in research articles, its use would facilitate non-expert readers’ understanding of the methodology used and its clinical meaning.
- Published
- 2014
- Full Text
- View/download PDF
41. Clinical utilisation of adenosine stress CMR and its influence on patient management in a tertiary cardiac centre.
- Author
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Sekhri, Neha, Timmis, Adam, Mahmood, Anjum, Sammut, Eva C., Westwood, Mark A., Davies, Ceri, Mohiddin, Saidi A., Weerackody, Roshan, Wragg, Andrew, Jones, Dan, Boubertakh, Redha, Petersen, Steffen E., and Mathur, Anthony
- Subjects
CARDIOVASCULAR disease diagnosis ,CONFERENCES & conventions ,HEART function tests ,MAGNETIC resonance imaging ,TERTIARY care - Abstract
An abstract of the article "Clinical utilisation of adenosine stress CMR and its influence on patient management in a tertiary cardiac centre," by Neha Sekhri, Adam Timmis, Anjum Mahmood, Eva C. Sammut, Mark A. Westwood, Ceri Davis, Saidi A. Mohiddin, Roshan Weerackody is presented.
- Published
- 2013
- Full Text
- View/download PDF
42. Quality of reporting in cardiac MRI, CT and SPECT diagnostic accuracy studies: Analysis of the impact of STARD criteria.
- Author
-
Maclean, Edd N., Stone, Ian S., Ceelen, Felix, Garcia-Albeniz, Xabier, Sommer, Wieland H., and Petersen, Steffen E.
- Subjects
BLOOD vessels ,CARDIOVASCULAR disease diagnosis ,COMPUTED tomography ,CONFERENCES & conventions ,MAGNETIC resonance imaging ,SINGLE-photon emission computed tomography - Abstract
An abstract of the article "Quality of reporting in cardiac MRI, CT and SPECT diagnostic accuracy studies: Analysis of the impact of STARD criteria," by Edd N. Maclean and colleagues is presented.
- Published
- 2013
- Full Text
- View/download PDF
43. Cardiovascular changes in patients with adult-onset growth hormone deficiency assessed by CMR.
- Author
-
Dattani, Abhishek, Thomas, Julia, Zemrak, Filip, Burchell, Thomas R., Petersen, Steffen E., Grossman, Ashley, Korbonits, Marta, and Davies, Ceri
- Subjects
SOMATOTROPIN - Abstract
An abstract of the article "Cardiovascular changes in patients with adult-onset growth hormone deficiency assessed by CMR," by Abhishek Dattani and colleagues is presented.
- Published
- 2012
- Full Text
- View/download PDF
44. Cardiac magnetic resonance perfusion imaging using a single intravenous line.
- Author
-
Weerackody, Roshan, Rathod, Krishnaraj S., Petersen, Steffen E., Mohiddin, Saidi A., Davies, Ceri, and Westwood, Mark
- Subjects
CARDIAC magnetic resonance imaging ,PERFUSION - Abstract
An abstract of the conference paper "Cardiac magnetic resonance perfusion imaging using a single intravenous line," by Roshan Weerackody and colleagues is presented.
- Published
- 2012
- Full Text
- View/download PDF
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