1. Biomaterials for hollow organ tissue engineering
- Author
-
Richard M. Day, Eseelle K. Hendow, Bernice Wright, Pauline Guhmann, Nina Parmar, and Panagiotis Sofokleous
- Subjects
0301 basic medicine ,Biocompatible ,Scaffold ,Medicine (miscellaneous) ,02 engineering and technology ,Dermatology ,Review ,Bioinformatics ,Regenerative medicine ,Biomaterials ,03 medical and health sciences ,Rheumatology ,Tissue engineering ,Medicine ,Hepatology ,Manufacturing process ,business.industry ,Gastroenterology ,Biomaterial ,021001 nanoscience & nanotechnology ,Biocompatible material ,030104 developmental biology ,Native tissue ,0210 nano-technology ,business ,Biomedical engineering - Abstract
Tissue engineering is a rapidly advancing field that is likely to transform how medicine is practised in the near future. For hollow organs such as those found in the cardiovascular and respiratory systems or gastrointestinal tract, tissue engineering can provide replacement of the entire organ or provide restoration of function to specific regions. Larger tissue-engineered constructs often require biomaterial-based scaffold structures to provide support and structure for new tissue growth. Consideration must be given to the choice of material and manufacturing process to ensure the de novo tissue closely matches the mechanical and physiological properties of the native tissue. This review will discuss some of the approaches taken to date for fabricating hollow organ scaffolds and the selection of appropriate biomaterials.
- Published
- 2016