Search

Your search keyword '"Miyazato, Yusuke"' showing total 4 results
Start Over Author "Miyazato, Yusuke" Publisher biomed central
4 results on '"Miyazato, Yusuke"'

3. Ancylostoma ceylanicum, novel etiological agent for traveler’s diarrhea—report of four Japanese patients who returned from Southeast Asia and Papua New Guinea

Author

Yoshikawa, Masahide, Ouji, Yukiteru, Hirai, Nobuyasu, Nakamura-Uchiyama, Fukumi, Yamada, Minoru, Arizono, Naoki, Akamatsu, Naoaki, Yoh, Takaharu, Kaya, Daisuke, Nakatani, Toshiya, Kikuchi, Eiryo, Katanami, Yuichi, Satoh, Kimitoshi, Maki, Ryosuke, Miyazato, Yusuke, Oba, Yuichiro, Kasahara, Kei, and Mikasa, Keiichi

Published
2018
Full Text
View/download PDF

4. Chromosomal coharboring of blaIMP-60 and mcr-9 in Enterobacter asburiae isolated from a Japanese woman with empyema: a case report.

Author

Miyazato, Yusuke, Iwamoto, Noriko, Usui, Masaru, Sato, Toyotaka, Miyoshi-Akiyama, Tohru, Nagashima, Maki, Mezaki, Kazuhisa, Hayakawa, Kayoko, and Ohmagari, Norio

Subjects
*ANTIBIOTICS, *PROTEINS, *CHROMOSOMES, *COLISTIN, *GRAM-negative bacteria, *NUCLEOTIDES, *GENES, *EMPYEMA, *DRUG resistance in microorganisms, *MICROBIAL sensitivity tests, *PHARMACODYNAMICS
Abstract

Background: Polymyxin E (colistin) is a last-resort antibiotic to treat infections caused by carbapenemase-producing Enterobacteriaceae (CPE). However, reports of CPEs resistant to colistin have been increasing, and the mcr genes are emerging as resistance mechanisms. Among them, plasmid-mediate mcr-9 is known to be associated with colistin resistance, whereas reports on chromosomal mcr-9 and its association with colistin resistance in humans are few.Case Presentation: We identified Enterobacter asburiae harboring mcr-9 and blaIMP-60 in the pleural fluid of a patient with empyema. The long-read sequencing technique revealed that these genes were located on its chromosome. Despite the lack of exposure to colistin, the organism showed microcolonies in the inhibition circle in the E-test and disk diffusion test. Antibiotic susceptibility testing by broth microdilution confirmed its resistance to colistin.Conclusion: Our case report showed that mcr-9 can be present not only on plasmids but also on the chromosome in E. asburiae, and that the presence of mcr-9 on its chromosome may influence its susceptibility to colistin. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results