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Start Over Author "Livi, Lorenzo" Publisher biomed central
6 results on '"Livi, Lorenzo"'

3. Loss of HER2 and decreased T-DM1 efficacy in HER2 positive advanced breast cancer treated with dual HER2 blockade: the SePHER Study

Author

Bon, Giulia, Pizzuti, Laura, Laquintana, Valentina, Loria, Rossella, Porru, Manuela, Marchiò, Caterina, Krasniqi, Eriseld, Barba, Maddalena, Maugeri-Saccà, Marcello, Gamucci, Teresa, Berardi, Rossana, Livi, Lorenzo, Ficorella, Corrado, Natoli, Clara, Cortesi, Enrico, Generali, Daniele, La Verde, Nicla, Cassano, Alessandra, Bria, Emilio, Moscetti, Luca, Michelotti, Andrea, Adamo, Vincenzo, Zamagni, Claudio, Tonini, Giuseppe, Barchiesi, Giacomo, Mazzotta, Marco, Marinelli, Daniele, Tomao, Silverio, Marchetti, Paolo, Valerio, Maria Rosaria, Mirabelli, Rosanna, Russo, Antonio, Fabbri, Maria Agnese, D’Ostilio, Nicola, Veltri, Enzo, Corsi, Domenico, Garrone, Ornella, Paris, Ida, Sarobba, Giuseppina, Giotta, Francesco, Garufi, Carlo, Cazzaniga, Marina, Del Medico, Pietro, Roselli, Mario, Sanguineti, Giuseppe, Sperduti, Isabella, Sapino, Anna, De Maria, Ruggero, Leonetti, Carlo, Di Leo, Angelo, Ciliberto, Gennaro, Falcioni, Rita, and Vici, Patrizia

Published
2020
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4. International validation of the EORTC QLQ-PRT20 module for assessment of quality of life symptoms relating to radiation proctitis: a phase IV study

Author

Halkett, Georgia K. B., Wigley, Charles Adam, Aoun, Samar M, Portaluri, Maurizio, Tramacere, Francesco, Livi, Lorenzo, Detti, Beatrice, Arcangeli, Stefano, Lund, Jo-Asmund, Kristensen, Are, McFadden, Nathalie, Grun, Arne, Bydder, Sean, Sackerer, Irina, Greimel, Elfriede, Spry, Nigel, and on behalf of the EORTC Quality of Life Group

Published
2018
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6. Sodium hyaluronate and chondroitin sulfate replenishment therapy can improve nocturia in men with post-radiation cystitis: results of a prospective pilot study.

Author

Gacci, Mauro, Saleh, Omar, Giannessi, Claudia, Detti, Beatrice, Livi, Lorenzo, Pasquetti, Eleonora Monteleone, Masoni, Tatiana, Agro, Enrico Finazzi, Li Marzi, Vincenzo, Minervini, Andrea, Carini, Marco, Gravas, Stavros, Oelke, Matthias, and Serni, Sergio

Subjects
PROSTATE cancer treatment, NOCTURIA, THERAPEUTIC use of hyaluronic acid, CHONDROITIN sulfates, NIGHT people, INTERSTITIAL cystitis, CANCER radiotherapy, GLYCOSAMINOGLYCANS, PATIENTS, THERAPEUTICS
Abstract

Background: Radiotherapy is one of the treatment options for prostate cancer (PCa) but up to 25 % of men report about severe nocturia (nocturnal voiding). The combination of hyaluronic acid (HA) and chondroitin sulfate (CS) resembles glycosaminoglycan (GAG) replenishment therapy. The aim of our study was to evaluate the impact of HA and CS on nocturia, in men with nocturia after PCa radiotherapy. Mnethods: Twenty-three consecutive patients with symptomatic cystitis after external radiotherapy for PCa were enrolled. Patients underwent bladder instillation therapy with HA and CS weekly for the first month and, afterwards, on week 6, 8 and 12. Nocturnal voiding frequency was assessed by item 3 (Q3) of the Interstitial Cystitis Symptoms Index (ICSI) and item 2 (Q2) of the Interstitial Cystitis Problem Index (ICPI). Data were analyzed with paired-samples T-test and adjusted for age. Results: Eighteen patients (78 %) reported about nocturia. Pre- and post-treatment ICSI-Q3 was 2.13 ± 0.28 and 1.61 ± 0.21 (-24.4 %, p = 0.001). With logistic regression analysis, both age and baseline ICSI-Q3 had a significant impact on nocturnal voiding frequency (r = 0.293, p = 0.011 and r = 0.970, p < 0.001). Pre- and post-treatment ICPI-Q2 was 1.87 ± 0.26 and 1.30 ± 0.25 (-30.5 %, p = 0.016); logistic regression analysis was without significant findings. Conclusion: Bladder instillation treatment with a combination of HA and CS was effective in reducing nocturnal voiding frequency in men with post-radiation bladder pain for PCa. Randomized, controlled trials with sham treatment are needed to confirm our result. [ABSTRACT FROM AUTHOR]

Published
2015
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