1. Metabolic syndrome, not menopause, is a risk factor for hypertension in peri-menopausal women
- Author
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Sang-Hyun Ihm, Kee Soo Kang, Kyoung Hwa Ha, Hae Young Lee, Sungha Park, Hyeon Chang Kim, Ho Kyung Sung, Gyu Chul Oh, and Chan Soon Park
- Subjects
medicine.medical_specialty ,lcsh:Internal medicine ,lcsh:Medicine ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,Diabetes mellitus ,Internal medicine ,Epidemiology ,Internal Medicine ,medicine ,030212 general & internal medicine ,Obesity ,Risk factor ,lcsh:RC31-1245 ,Angiology ,business.industry ,Incidence (epidemiology) ,Research ,lcsh:R ,medicine.disease ,Metabolic syndrome ,Menopause ,Hypertension ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background It has been long debated whether menopause itself is a risk factor for hypertension in peri-menopausal women. We aimed to assess the association between menopause and hypertension, and whether metabolic syndrome (MetS) has an influence on its effect. Methods Data for 1502 women aged 42 to 53 from the Korean Genome and Epidemiology Study (KoGES) database were retrospectively analyzed. The KoGES database consists of 10,038 participants, of which 52.6% (5275) were female. Subjects were followed up for 4 years, and compared according to menopausal status. Additionally, 1216 non-hypertensive subjects were separately analyzed to assess whether a change in menopausal status was associated with development of hypertension. Results The prevalence of hypertension, diabetes, and MetS for menopausal and non-menopausal subjects at baseline was 24.4% vs. 16.7%, 5.8% vs. 2.9%, and 25.4% vs. 16.6%, respectively (p
- Published
- 2018