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174 results on '"Cain C"'

46. The effect of apple cider vinegar on lipid profiles and glycemic parameters: a systematic review and meta-analysis of randomized clinical trials

Author

Amir Hadi, Ahmad Esmaillzadeh, Cain C T Clark, Ameneh Najafgholizadeh, and Makan Pourmasoumi

Subjects
Blood Glucose, medicine.medical_specialty, Glycemic indices, 030209 endocrinology & metabolism, Review, Cochrane Library, law.invention, 03 medical and health sciences, Other systems of medicine, 0302 clinical medicine, Clinical trials, Randomized controlled trial, law, Internal medicine, Medicine, Glucose homeostasis, Humans, Insulin, 030212 general & internal medicine, skin and connective tissue diseases, Glycemic, Acetic Acid, Randomized Controlled Trials as Topic, Glycated Hemoglobin, business.industry, Cholesterol, HDL, virus diseases, Lipid profiles, Cholesterol, LDL, Apple cider vinegar, Clinical trial, Meta-analysis, Glycemic index, Cholesterol, Complementary and alternative medicine, Diabetes Mellitus, Type 2, Malus, business, RZ201-999
Abstract

Background Elevated lipid profiles and impaired glucose homeostasis are risk factors for several cardiovascular diseases (CVDs), which, subsequently, represent a leading cause of early mortality, worldwide. The aim of the current study was to conduct a systematic review and meta-analysis of the effect of apple cider vinegar (ACV) on lipid profiles and glycemic parameters in adults. Methods A systematic search was conducted in electronic databases, including Medline, Scopus, Cochrane Library, and Web of Knowledge, from database inception to January 2020. All clinical trials which investigated the effect of ACV on lipid profiles and glycemic indicators were included. Studies were excluded if ACV was used in combination with other interventions or when the duration of intervention was Results Overall, nine studies, including 10 study arms, were included in this meta-analysis. We found that ACV consumption significantly decreased serum total cholesterol (− 6.06 mg/dL; 95% CI: − 10.95, − 1.17; I2: 39%), fasting plasma glucose (− 7.97 mg/dL; 95% CI: − 13.74, − 2.21; I2: 75%), and HbA1C concentrations (− 0.50; 95% CI: − 0.90, − 0.09; I2: 91%). No significant effect of ACV consumption was found on serum LDL-C, HDL-C, fasting insulin concentrations, or HOMA-IR. The stratified analysis revealed a significant reduction of serum TC and TG in a subgroup of patients with type 2 diabetes, those who took ≤15 mL/day of ACV, and those who consumed ACV for > 8-weeks, respectively. Furthermore, ACV consumption significantly decreased FPG levels in a subgroup of studies that administered ACV for > 8-weeks. Further, ACV intake appeared to elicit an increase in FPG and HDL-C concentrations in apparently healthy participants. Conclusion We found a significant favorable effect of ACV consumption on FPG and blood lipid levels.

Published
2021

47. The association between dietary acid load and muscle strength among Iranian adults

Author

Samira Davarzani, Cain C T Clark, Saba Mohammadpour, Sakineh Shab-Bidar, Farhang Djafari, and Kurosh Djafarian

Subjects
0301 basic medicine, medicine.medical_specialty, lcsh:Medicine, 030209 endocrinology & metabolism, Iran, Muscle mass, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Alkalogenic diet, medicine, Limited evidence, lcsh:Science (General), lcsh:QH301-705.5, 030109 nutrition & dietetics, Hand Strength, business.industry, Muscle strength, Confounding, lcsh:R, fungi, Acidogenic diet, Food frequency questionnaire, General Medicine, Acid load, Acid production, Diet, Research Note, Dietary acid load, Endocrinology, Cross-Sectional Studies, lcsh:Biology (General), business, Acids, lcsh:Q1-390
Abstract

Objective There is limited evidence regarding the association between dietary acid load and muscle strength. Thus, in this study, we investigated the association between dietary acid–base load indices and muscle strength among Iranian adults. Results This cross-sectional study was conducted on 270 Iranian adults, aged 18–70 year. Dietary acid load indexes, were calculated by using a validated 168-item semi-quantitative food frequency questionnaire (FFQ). Muscle strength was measured by a digital handgrip dynamometer. There was a significant increase in mean muscle strength of left-hand (MSL), muscle strength of right-hand (MSR) and the mean of the MSL and MSR (MMS) across tertiles of Potential Renal Acid Load (PRAL), Net Endogenous Acid Production (NEAP), and Dietary Acid Load (DAL). Significant linear relationships between PRAL and; MSL (β = 0.24, p 0.001), MSR (β = 0.23, p 0.001) and MMS (β = 0.24, p 0.001), between NEAP and MSL (β = 0.21, p 0.001), MSR (β = 0.19, p = 0.002), and MMS (β = 0.20, p = 0.001) and between DAL and MSL (β = 0.25, p 0.001), MSR (β = 0.23, p 0.001) and MMS (β = 0.24, p

Published
2020

48. Listening to music during a repeated sprint test improves performance and psychophysiological responses in healthy and physically active male adults

Author

Educacion Fisica y Deportiva, Jebabli, Nidhal, Ben Aabderrahman, Abderraouf, Chtourou, Hamdi, Ouerghi, Nejmeddine, Rhibi, Fatma, Govindasamy, Karuppasamy, Saeidi, Ayoub, Clark, Cain C. T., Granacher, Urs, Zouhal, Hassane, Boullosa Álvarez, Daniel Alexandre, Educacion Fisica y Deportiva, Jebabli, Nidhal, Ben Aabderrahman, Abderraouf, Chtourou, Hamdi, Ouerghi, Nejmeddine, Rhibi, Fatma, Govindasamy, Karuppasamy, Saeidi, Ayoub, Clark, Cain C. T., Granacher, Urs, Zouhal, Hassane, and Boullosa Álvarez, Daniel Alexandre

Abstract

[EN] Background It is well-documented that listening to music has the potential to improve physical performance during intense physical exercise. Less information is available on the timing of music application. This study aimed to investigate the effects of listening to preferred music during the warm up of a subsequent test or during the test on performance of repeated sprint sets (RSS) in adult males. Methods In a randomized cross-over design, 19 healthy males (age, 22.1 ± 1.2 years; body mass, 72.7 ± 9.3 kg; height, 1.79 ± 0.06 m; BMI, 22.6 ± 2.2 kg m−2) performed a test including 2 sets of 5*20-m repeated-sprints under one of three conditions: listening to preferred music during the test; listening to preferred music during the warm-up; or not listening to music. The assessed parameters comprised RSS performance indices, blood lactate, heart rate, the pacing strategy profile, rating of perceived exertion, and a feeling scale. Results For performance indices during set 1 of the RSS test, we found a significant decrease in total sum sequence, fast time index and fatigue index in the listening to preferred music condition compared to the no music condition (total sum sequence: p = 0.006, d = 0.93; fast time index: p = 0.003, d = 0.67; fatigue index: p < 0.001; d = 1.30) and the listening to preferred music during the warm-up condition (fast time index: p = 0.002; d = 1.15; fatigue index: p = 0.006; d = 0.74). However, there was no significant effect of listening to preferred music on physical performance during set 2 of the RSS test. Compared to the no music condition, blood lactate concentrations were higher in the listening to preferred music during the test condition (p = 0.025; d = 0.92). In addition, listening to preferred music appears not to have an effect on heart rate, the pacing strategy profile, perceived exertion, and affective responses before, during and after the RSS test. Conclusion Findings from this study revealed that RSS performances were bette

49. The association between dietary antioxidant quality score and intensity and frequency of migraine headaches among women: a cross-sectional study.

Author

Hajishizari S, Mirzababaei A, Abaj F, Bahrampour N, Moradi S, C T Clark C, and Mirzaei K

Subjects
Humans, Female, Cross-Sectional Studies, Adult, Surveys and Questionnaires, Middle Aged, Severity of Illness Index, Migraine Disorders epidemiology, Antioxidants administration & dosage, Antioxidants analysis, Diet statistics & numerical data, Diet methods
Abstract

Background: Migraine is an episodic disorder and a frequent form of headache. An impaired balance between free radical production and an impaired antioxidant defense system leading to oxidative damage may play a major role in migraine etiology. We sought to investigate whether dietary antioxidant quality score (DAQS) is associated with migraine intensity and frequency among women suffering from migraine., Methods: This cross-sectional study was conducted on 265 women. The data related to anthropometric measures and dietary intake were collected. DAQS score was calculated based on FFQ (food frequency questionnaire) vs. the reference daily intake (RDI) quantity. To measure migraine intensity, the migraine disability assessment questionnaire (MIDAS) and visual analog scale (VAS) were used. The frequency of headaches was defined as the days the participants had headaches in the last month and a 30-day headache diary was used., Results: The results of the study demonstrated that VAS, MIDAS, and frequency of headaches were reduced significantly from the low DAQS (poor quality of antioxidants) to high DAQS (high quality of antioxidants) after adjusting covariates. Also, multinomial regression showed there was an inverse association between higher DAQS and the frequency of headaches. In the adjusted model, subjects with the higher DAQS were 69% less likely to have moderate migraine disability, compared with those with the lower DAQS. Linear regression showed, there was an inverse association between vitamin C intake and the grades of pain severity.َAlso in a crude model, a negative association was found between vitamin E and the frequency of headaches., Conclusion: In conclusion, Participants with higher DAQS had lower migraine intensity and headache frequency. In addition, the consumption of vitamin C may potentially associate with decreasing the severity of headaches. Dietary antioxidants should be monitored closely in individuals suffering from migraine., (© 2024. The Author(s).)

Published
2024
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50. Improving routine use of clinical pathway decision support through integration of an EHR with a clinical library resource designed to provide evidence-based guidance within oncology workflows.

Author

Ichiuji M, Asakura L, Cain C, Aye N, Kolevska T, Chen D, Brasfield FM, and Kotak D

Subjects
Humans, Evidence-Based Medicine, Electronic Health Records, Decision Support Systems, Clinical, Critical Pathways, Medical Oncology, Workflow
Abstract

Background: The rapid evolution, complexity, and specialization of oncology treatment makes it challenging for physicians to provide care based on the latest and best evidence. We hypothesized that physicians would use evidence-based trusted care pathways if they were easy to use and integrated into clinical workflow at the point of care., Methods: Within a large integrated care delivery system, we assembled clinical experts to define and update drug treatment pathways, encoded them as flowcharts in an online library integrated with the electronic medical record, communicated expectations that clinicians would use these pathways for every eligible patient, and combined data from multiple sources to understand usage over time., Results: We were able to achieve > 75% utilization of eligible protocols ordered through these pathways within two years, with > 90% of individual oncologists having consulted the pathway at least once, despite no requirements or external incentives associated with pathway usage. Feedback from users contributed to improvements and updates to the guidance., Conclusions: By making our clinical decision support easily accessible and actionable, we find that we have made considerable progress toward our goal of having physicians consult the latest evidence in their treatment decisions., (© 2024. The Author(s).)

Published
2024
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