1. Aspirin hypersensitivity in Iranian patients with chronic rhinosinusitis and nasal polyposis: prevalence and comorbid factors
- Author
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Ahmad Bahrami, hossein esmaeilzadeh, Negar Mortazavi, Mohammad Nabavi, M Fallahpour, Mohammad Hassan Bemanian, Saba Arshi, and Nima Rezaei
- Subjects
Pulmonary and Respiratory Medicine ,Allergy ,medicine.medical_specialty ,Aspirin ,Chronic rhinosinusitis ,business.industry ,Immunology ,Total ige ,Aspirin hypersensitivity ,medicine.disease ,Gastroenterology ,digestive system diseases ,surgical procedures, operative ,Internal medicine ,Poster Presentation ,otorhinolaryngologic diseases ,medicine ,Immunology and Allergy ,In patient ,Aspirin exacerbated respiratory disease ,Nasal polyps ,business ,medicine.drug - Abstract
Background Aspirin (ASA) hypersensitivity is frequent in patients with chronic rhinosinusitis and nasal polyps (CRSwNP), which is called aspirin exacerbated respiratory disease (AERD). However, there are few studies on evaluating the prevalence of ASA hypersensitivity in patients with nasal polyps (NPs), using the oral aspirin challenge test. This study was designed to determine the frequency of ASA hypersensitivity and factors associated with ASA hypersensitivity in patients with CRSwNP. Methods Eighty Iranian patients (43 women and 37 men) with CRSwNP were enrolled in this study. Extension of NPs was evaluated by endoscopic examination. A single day, oral aspirin challenge (OAC) was used to detect ASA hypersensitivity. Atopic evaluation was performed, using skin prick test, nasal smear, blood eosinophil count, and serum total IgE. Results
- Published
- 2014