43 results on '"Courneya, Kerry S."'
Search Results
2. Rationale and design of the Diet Restriction and Exercise-induced Adaptations in Metastatic breast cancer (DREAM) study: a 2-arm, parallel-group, phase II, randomized control trial of a short-term, calorie-restricted, and ketogenic diet plus exercise during intravenous chemotherapy versus usual care
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Kirkham, Amy A., King, Karen, Joy, Anil A., Pelletier, André B., Mackey, John R., Young, Kelvin, Zhu, Xiaofu, Meza-Junco, Judith, Basi, Sanraj K., Hiller, Julie Price, Brkin, Tina, Michalowski, Bonnie, Pituskin, Edith, Paterson, D. Ian, Courneya, Kerry S., Thompson, Richard B., and Prado, Carla M.
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- 2021
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3. Aerobic and resistance exercise improves Reynolds risk score in overweight or obese breast cancer survivors
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Lee, Kyuwan, Sami, Nathalie, Tripathy, Debu, Demark-Wahnefried, Wendy, Norris, Mary K., Courneya, Kerry S., and Dieli-Conwright, Christina M.
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- 2020
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4. Translating research into practice: outcomes from the Healthy Living after Cancer partnership project
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Eakin, Elizabeth G., Reeves, Marina M., Goode, Ana D., Winkler, Elisabeth A. H., Vardy, Janette L., Boyle, Frances, Haas, Marion R., Hiller, Janet E., Mishra, Gita D., Jefford, Michael, Koczwara, Bogda, Saunders, Christobel M., Chapman, Kathy, Hing, Liz, Boltong, Anna G., Lane, Katherine, Baldwin, Polly, Millar, Lesley, McKiernan, Sandy, Demark-Wahnefried, Wendy, Courneya, Kerry S., Job, Jennifer, Reid, Natasha, Robson, Erin, Moretto, Nicole, Gordon, Louisa, and Hayes, Sandra C.
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- 2020
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5. Patterns and predictors of exercise behavior during 24 months of follow-up after a supervised exercise program during breast cancer chemotherapy
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An, Ki-Yong, Kang, Dong-Woo, Morielli, Andria R., Friedenreich, Christine M., Reid, Robert D., McKenzie, Donald C., Gelmon, Karen, Mackey, John R., and Courneya, Kerry S.
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- 2020
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6. Correction to: Rationale and design of the Caloric Restriction and Exercise protection from Anthracycline Toxic Effects (CREATE) study: a 3-arm parallel group phase II randomized controlled trial in early breast cancer
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Kirkham, Amy A., Ian Paterson, D., Prado, Carla M., Mackey, John R., Courneya, Kerry S., Pituskin, Edith, and Thompson, Richard B.
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- 2019
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7. Peer support for the maintenance of physical activity and health in cancer survivors: the PEER trial - a study protocol of a randomised controlled trial
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Adlard, Kirsten N., Jenkins, David G., Salisbury, Chloe E., Bolam, Kate A., Gomersall, Sjaan R., Aitken, Joanne F., Chambers, Suzanne K., Dunn, Jeff C., Courneya, Kerry S., and Skinner, Tina L.
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- 2019
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8. The impact of exercise on growth factors (VEGF and FGF2): results from a 12-month randomized intervention trial
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Brenner, Darren R., Ruan, Yibing, Adams, Scott C., Courneya, Kerry S., and Friedenreich, Christine M.
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- 2019
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9. Rationale and design of the Caloric Restriction and Exercise protection from Anthracycline Toxic Effects (CREATE) study: a 3-arm parallel group phase II randomized controlled trial in early breast cancer
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Kirkham, Amy A., Paterson, D. Ian, Prado, Carla M., Mackey, John M., Courneya, Kerry S., Pituskin, Edith, and Thompson, Richard B.
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- 2018
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10. Aerobic and resistance exercise improves physical fitness, bone health, and quality of life in overweight and obese breast cancer survivors: a randomized controlled trial
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Dieli-Conwright, Christina M, Courneya, Kerry S, Demark-Wahnefried, Wendy, Sami, Nathalie, Lee, Kyuwan, Sweeney, Frank C, Stewart, Christina, Buchanan, Thomas A, Spicer, Darcy, Tripathy, Debu, Bernstein, Leslie, and Mortimer, Joanne E
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- 2018
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11. A qualitative study examining newly diagnosed breast cancer patients' experiences of participating in the Alberta Moving Beyond Breast Cancer (AMBER) prospective cohort study.
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Corcoran, Lynn, Friedenreich, Christine M., McNeely, Margaret L., Culos-Reed, Nicole S., Bell, Gordon, Dickau, Leanne, Courneya, Kerry S., and Vallance, Jeff K.
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PATIENTS' attitudes ,BREAST cancer ,CANCER patients ,COHORT analysis ,LONGITUDINAL method - Abstract
Background: Decisions to participate in cancer trials are associated with uncertainty, distress, wanting to help find a cure, the hope for benefit, and altruism. There is a gap in the literature regarding research examining participation in prospective cohort studies. The aim of this study was to examine the experiences of newly diagnosed women with breast cancer participating in the AMBER Study to identify potential strategies to support patients' recruitment, retention, and motivation. Methods: Newly diagnosed breast cancer patients were recruited from the Alberta Moving Beyond Breast Cancer (AMBER) cohort study. Data were collected using semi-structured conversational interviews with 21 participants from February to May 2020. Transcripts were imported into NVivo software for management, organization, and coding. Inductive content analysis was undertaken. Results: Five main concepts associated with recruitment, retention, and motivation to participate were identified. These main concepts included: (1) personal interest in exercise and nutrition; (2) investment in individual results; (3) personal and professional interest in research; (4) burden of assessments; (5) importance of research staff. Conclusions: Breast cancer survivors participating in this prospective cohort study had numerous reasons for participating and these reasons could be considered in future studies to enhance participant recruitment and retention. Improving recruitment and retention in prospective cancer cohort studies could result in more valid and generalizable study findings that could improve the care of cancer survivors. [ABSTRACT FROM AUTHOR]
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- 2023
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12. Effects of prescribed aerobic exercise volume on physical activity and sedentary time in postmenopausal women: a randomized controlled trial
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McNeil, Jessica, Farris, Megan S., Ruan, Yibing, Merry, Heather, Lynch, Brigid M., Matthews, Charles E., Courneya, Kerry S., and Friedenreich, Christine M.
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- 2018
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13. Believability of messages about preventing breast cancer and heart disease through physical activity.
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Berry, Tanya R., Jones, Kelvin E., Courneya, Kerry S., McGannon, Kerry R., Norris, Colleen M., Rodgers, Wendy M., and Spence, John C.
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- 2018
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14. Exercise during and after neoadjuvant rectal cancer treatment (the EXERT trial): study protocol for a randomized controlled trial.
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Morielli, Andria R., Usmani, Nawaid, Boulé, Normand G., Severin, Diane, Tankel, Keith, Nijjar, Tirath, Joseph, Kurian, Fairchild, Alysa, and Courneya, Kerry S.
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RECTAL cancer ,CHEMORADIOTHERAPY ,HAND-foot syndrome ,CANCER patients ,CARDIOPULMONARY system - Abstract
Background: Standard treatment for locally advanced rectal cancer includes 5-6 weeks of neoadjuvant chemoradiotherapy (NACRT) followed by total mesorectal excision 6-8 weeks later. NACRT improves local disease control and surgical outcomes but also causes side effects including fatigue, diarrhea, hand-foot syndrome, and physical deconditioning that may impede quality of life (QoL), treatment completion, treatment response, and long-term prognosis. Interventions to improve treatment outcomes and manage side effects that are safe, tolerable and low-cost are highly desirable. Exercise has been shown to improve some of these outcomes in other cancer patient groups but no study to date has examined the potential benefits (and harms) of exercise training during and after NACRT for rectal cancer.Methods/design: The Exercise During and After Neoadjuvant Rectal Cancer Treatment (EXERT) trial is a single-center, prospective, two-armed, phase II randomized controlled trial designed to test the preliminary efficacy of exercise training in this clinical setting and to further evaluate its feasibility and safety. Participants will be 60 rectal cancer patients scheduled to receive long-course NACRT followed by total mesorectal excision. Participants will be randomly assigned to exercise training or usual care. Participants in the exercise training group will be asked to complete three supervised, high-intensity interval training sessions/week during NACRT and ≥ 150 min/week of unsupervised, moderate-to-vigorous-intensity, continuous exercise training after NACRT prior to surgery. Participants in the usual care group will be asked not to increase their exercise from baseline. Assessments will be completed pre NACRT, post NACRT, and pre surgery. The primary endpoint will be cardiorespiratory fitness (VO2 peak) at the post-NACRT time point assessed by a graded exercise test. Secondary endpoints will include functional fitness assessed by the Senior's Fitness Test, QoL assessed by the European Organisation of Research and Treatment of Cancer, and symptom management assessed by the M.D. Anderson Symptom Inventory. Exploratory clinical endpoints will include treatment toxicities, treatment completion, treatment response, and surgical complications.Discussion: If the preliminary findings of EXERT are positive, additional research will be warranted to confirm whether exercise is an innovative treatment to maintain QoL, manage side effects, and/or improve treatment outcomes in rectal cancer patients.Trial Registration: ClinicalTrials.gov, ID: NCT03082495 . Registered on 9 February, 2017. [ABSTRACT FROM AUTHOR]- Published
- 2018
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15. Correlates of meeting the combined and independent aerobic and strength exercise guidelines in hematologic cancer survivors.
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Vallerand, James R., Rhodes, Ryan E., Walker, Gordon J., and Courneya, Kerry S.
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AEROBIC exercises ,ANALYSIS of variance ,CANCER patients ,CHI-squared test ,COMPARATIVE studies ,CONFIDENCE intervals ,EPIDEMIOLOGICAL research ,HEALTH behavior ,HEALTH policy ,MOTIVATION (Psychology) ,MULTIVARIATE analysis ,POSTAL service ,PROBABILITY theory ,QUESTIONNAIRES ,REFLECTION (Philosophy) ,RESEARCH funding ,SCALE analysis (Psychology) ,STATISTICS ,LOGISTIC regression analysis ,DATA analysis ,SOCIOECONOMIC factors ,EDUCATIONAL attainment ,BODY mass index ,PLANNED behavior theory ,CROSS-sectional method ,DESCRIPTIVE statistics ,HEMATOLOGIC malignancies ,RESISTANCE training ,ODDS ratio - Abstract
Background: Most previous research on the correlates of physical activity has examined the aerobic or strength exercise guidelines separately. Such an approach does not allow an examination of the correlates of meeting the combined guidelines versus a single guideline, or one guideline versus the other. Here, we report the prevalence and correlates of meeting the combined and independent exercise guidelines in hematologic cancer survivors (HCS). Methods: In a population-based, cross-sectional survey of 606 HCS from Alberta, Canada using a mailed questionnaire, we obtained separate assessments of aerobic and strength exercise behaviors, as well as separate assessments for motivations, regulations, and reflective processes using the multi-process action control framework (M-PAC). Results: Overall, 22% of HCS met the combined exercise guideline, 22% met aerobic-only, 10% met strength-only, and 46% met neither exercise guideline. HCS were more likely to meet the combined guideline over the aerobic-only guideline if they had no children living at home, and over both the aerobic and strength-only guidelines if they had completed university. As hypothesized, those meeting the combined guideline also had a more favorable strength- specific M-PAC profile (i.e., motivations, regulations, and reflective processes) than those meeting the aerobic-only guideline, and a more favorable aerobic-specific M-PAC profile than those meeting the strength-only guideline. Interestingly and unexpectedly, HCS meeting the combined guidelines also reported significantly greater aerobic- specific perceived control, planning, and obligation/regret than those meeting the aerobic-only guideline, and greater strength-specific perceived control, planning, and obligation/regret than those meeting the strength-only guideline. Conclusions: Few HCS are meeting the combined exercise guidelines. M-PAC based variables are strong correlates of meeting the combined guidelines compared to aerobic or strength only guidelines. Strategies to help HCS meet the combined guidelines may need to promote more favorable behavioral regulations and reflective processes for both types of exercise rather than just the type of exercise in which HCS are deficient. [ABSTRACT FROM AUTHOR]
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- 2017
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16. Perceived benefits and barriers to exercise for recently treated patients with multiple myeloma: a qualitative study
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Craike, Melinda J., Hose, Kaye, Courneya, Kerry S., Harrison, Simon J., Livingston, Patricia M., Craike, Melinda J., Hose, Kaye, Courneya, Kerry S., Harrison, Simon J., and Livingston, Patricia M.
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Background: Understanding the physical activity experiences of patients with multiple myeloma (MM) is essential to inform the development of evidence-based interventions and to quantify the benefits of physical activity. The aim of this study was to gain an in-depth understanding of the physical activity experiences and perceived benefits and barriers to physical activity for patients with MM. Methods: This was a qualitative study that used a grounded theory approach. Semi-structured interviews were conducted in Victoria, Australia by telephone from December 2011-February 2012 with patients who had been treated for MM within the preceding 2 – 12 months. Interviews were transcribed and analysed using the constant comparison coding method to reduce the data to themes. Gender differences and differences between treatment groups were explored. Results: Twenty-four interviews were completed. The sample comprised 13 females (54%), with a mean age of 62 years (SD = 8.8). Sixteen (67%) participants had received an autologous stem cell transplant (ASCT). All participants currently engaged in a range of light to moderate intensity physical activity; walking and gardening were the most common activities. Recovery from the symptoms of MM and side effects of therapy, psychological benefits, social factors and enjoyment were important benefits of physical activity. Barriers to physical activity predominately related to the symptoms of MM and side effects of therapy, including pain, fatigue, and fear of infection. Low self- motivation was also a barrier. Women participated in a more diverse range of physical activities than men and there were gender differences in preferred type of physical activity. Women were more likely to report psychological and social benefits; whereas men reported physical activity as a way to keep busy and self- motivation was a barrier. Patients treated with an ASCT more often reported affective benefits of participation in p
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- 2013
17. The Alberta Moving Beyond Breast Cancer (AMBER) Cohort Study: Recruitment, Baseline Assessment, and Description of the First 500 Participants.
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Courneya, Kerry S., McNeely, Margaret L., Culos-Reed, S. Nicole, Vallance, Jeff K., Bell, Gordon J., Mackey, John R., Matthews, Charles E., Morielli, Andria R., Cook, Diane, MacLaughlin, Sarah, Farris, Megan S., Voaklander, Stephanie, O'Reilly, Rachel, and Friedenreich, Christine M.
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BREAST cancer diagnosis , *BREAST cancer patients , *PHYSICAL activity , *SEDENTARY behavior , *LYMPHEDEMA , *BLOOD collection , *BREAST tumor treatment , *BREAST tumors , *EXERCISE , *HEALTH status indicators , *LONGITUDINAL method , *PHYSICAL fitness , *RESEARCH funding , *PATIENT selection , *SEDENTARY lifestyles , *CANCER & psychology - Abstract
Background: To our knowledge, the Alberta Moving Beyond Breast Cancer (AMBER) Study is the first and only prospective cohort study of breast cancer survivors that includes objectively-measured physical activity (PA), sedentary behavior, health-related fitness (HRF), and biologic mechanisms focused on understanding breast cancer outcomes. The purpose of the present study was to report on the feasibility of recruitment, baseline measurement completion, and the representativeness of the first 500 participants.Methods: AMBER is enrolling newly diagnosed stage I (≥T1c) to IIIc breast cancer survivors in Alberta, Canada. Baseline assessments are completed soon after diagnosis and include cardiorespiratory fitness, musculoskeletal fitness, body composition, objective and self-reported PA and sedentary behavior, lymphedema, and blood collection.Results: Between July 2012 and November 2014, AMBER recruited its first 500 participants from a pool of 1,447 (35 %) eligible breast cancer survivors. Baseline HRF assessments were completed on ≥85 % of participants with the exception of upper body strength. Collection of ≥4 days/week of monitoring for the Actigraph GT3X® and ActivPAL® were obtained from 90 % of participants. Completion rates were also high for blood (99 %), lymphedema (98 %), and questionnaires (95 %) including patient-reported outcomes and correlates of exercise. The first 500 participants in AMBER are an average age of 56 years, 60 % are overweight or obese, and 58 % have disease stage II or III.Conclusion: Despite the modest recruitment rate and younger age, AMBER has demonstrated that many newly diagnosed breast cancer survivors are willing and able to complete a wide array of sophisticated and physically demanding HRF and PA assessments soon after diagnosis. AMBER is a unique breast cancer survivor cohort that may inform future randomized controlled trials on lifestyle and breast cancer outcomes as well as PA behavior change in breast cancer survivors. Moreover, AMBER may also inform guidelines on PA, sedentary behavior, and HRF for improving breast cancer outcomes and survivorship. [ABSTRACT FROM AUTHOR]- Published
- 2016
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18. Physical activity in advanced cancer patients: a systematic review protocol.
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Lowe, Sonya S., Tan, Maria, Faily, Joan, Watanabe, Sharon M., and Courneya, Kerry S.
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ONCOLOGY ,TUMORS ,PALLIATIVE treatment - Abstract
Background: Progressive, incurable cancer is associated with increased fatigue, increased muscle weakness, and reduced physical functioning, all of which negatively impact quality of life. Physical activity has demonstrated benefits on cancer-related fatigue and physical functioning in early-stage cancer patients; however, its impact on these outcomes in end-stage cancer has not been established. The aim of this systematic review is to determine the potential benefits, harms, and effects of physical activity interventions on quality of life outcomes in advanced cancer patients. Methods/design: A systematic review of peer-reviewed literature on physical activity in advanced cancer patients will be undertaken. Empirical quantitative studies will be considered for inclusion if they present interventional or observational data on physical activity in advanced cancer patients. Searches will be conducted in the following electronic databases: CINAHL; CIRRIE Database of International Rehabilitation Research; Cochrane Database of Systematic Reviews (CDSR); Database of Abstracts of Reviews of Effects (DARE); Cochrane Central Register of Controlled Trials (CENTRAL); EMBASE; MEDLINE; PEDro: the Physiotherapy Evidence Database; PQDT; PsycInfo; PubMed; REHABDATA; Scopus; SPORTDiscus; and Web of Science, to identify relevant studies of interest. Additional strategies to identify relevant studies will include citation searches and evaluation of reference lists of included articles. Titles, abstracts, and keywords of identified studies from the search strategies will be screened for inclusion criteria. Two independent reviewers will conduct quality appraisal using the Effective Public Health Practice Project Quality Assessment Tool for Quantitative Studies (EPHPP) and the Cochrane risk of bias tool. A descriptive summary of included studies will describe the study designs, participant and activity characteristics, and objective and patient-reported outcomes. Discussion: This systematic review will summarize the current evidence base on physical activity interventions in advanced cancer patients. The findings from this systematic review will identify gaps to be explored by future research studies and inform future practice guideline development of physical activity interventions in advanced cancer patients. [ABSTRACT FROM AUTHOR]
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- 2016
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19. Physical activity interests and preferences of cancer patients with brain metastases: a cross-sectional survey.
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Lowe, Sonya S., Danielson, Brita, Beaumont, Crystal, Watanabe, Sharon M., and Courneya, Kerry S.
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BRAIN ,CHI-squared test ,STATISTICAL correlation ,INTERVIEWING ,LUNG tumors ,METASTASIS ,PALLIATIVE treatment ,RESEARCH funding ,TUMORS ,ACCELEROMETRY ,CROSS-sectional method ,PHYSICAL activity ,DATA analysis software ,PATIENTS' attitudes ,DESCRIPTIVE statistics ,DISEASE complications - Abstract
Background: Physical activity has been shown to positively impact cancer-related fatigue, physical functioning and quality of life outcomes in early stage cancer patients, however its role at the end stage of cancer has yet to be determined. Brain metastases are amongst the most common neurological complications of advanced cancer, with significant deterioration in fatigue and quality of life. The purpose of the present study was to examine the physical activity interests and preferences of cancer patients with brain metastases initiating palliative whole brain radiotherapy. Methods: Thirty-one patients aged 18 years or older, cognitively intact, diagnosed with brain metastases, and with Palliative Performance Scale scores of greater than 30 %, were recruited from a multidisciplinary outpatient brain metastases clinic. An interviewer-administered survey was used to assess physical activity interests and preferences of participants who were embarking upon palliative whole brain radiotherapy. Results: 87 % (n = 27) of participants felt that physical activity was important, however there was limited interest in n participating in a structured program at the onset of palliative whole brain radiotherapy. Lung cancer diagnosis was associated with being less interested in participating in a physical activity program, and feeling less able to participate in a physical activity program at the onset of palliative whole brain radiotherapy. Conclusions: Cancer patients with brain metastases demonstrate limited interest and varied preferences for physical activity during palliative whole brain radiotherapy. Additional pilot work with this patient population is needed before physical activity interventions can be tested in clinical research. [ABSTRACT FROM AUTHOR]
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- 2016
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20. Healthy Living after Cancer: a dissemination and implementation study evaluating a telephone-delivered healthy lifestyle program for cancer survivors.
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Eakin, Elizabeth G., Hayes, Sandra C., Haas, Marion R., Reeves, Marina M., Vardy, Janette L., Boyle, Frances, Hiller, Janet E., Mishra, Gita D., Goode, Ana D., Jefford, Michael, Koczwara, Bogda, Saunders, Christobel M., Demark-Wahnefried, Wendy, Courneya, Kerry S., Schmitz, Kathryn H., Girgis, Afaf, White, Kate, Chapman, Kathy, Boltong, Anna G., and Lane, Katherine
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CANCER patients ,CANCER invasiveness ,PHYSICAL activity ,REGULATION of body weight ,EVIDENCE-based medicine ,LIFESTYLES & health ,TUMORS & psychology ,COST effectiveness ,DIET ,EXERCISE ,EXPERIMENTAL design ,HEALTH promotion ,TELEPHONES ,TUMORS ,SOCIAL support ,LIFESTYLES ,ECONOMICS - Abstract
Background: Given evidence shows physical activity, a healthful diet and weight management can improve cancer outcomes and reduce chronic disease risk, the major cancer organisations and health authorities have endorsed related guidelines for cancer survivors. Despite these, and a growing evidence base on effective lifestyle interventions, there is limited uptake into survivorship care.Methods/design: Healthy Living after Cancer (HLaC) is a national dissemination and implementation study that will evaluate the integration of an evidence-based lifestyle intervention for cancer survivors into an existing telephone cancer information and support service delivered by Australian state-based Cancer Councils. Eligible participants (adults having completed cancer treatment with curative intent) will receive 12 health coaching calls over 6 months from Cancer Council nurses/allied health professionals targeting national guidelines for physical activity, healthy eating and weight control. Using the RE-AIM evaluation framework, primary outcomes are service-level indicators of program reach, adoption, implementation/costs and maintenance, with secondary (effectiveness) outcomes of patient-reported anthropometric, behavioural and psychosocial variables collected at pre- and post-program completion. The total participant accrual target across four participating Cancer Councils is 900 over 3 years.Discussion: The national scope of the project and broad inclusion of cancer survivors, alongside evaluation of service-level indicators, associated costs and patient-reported outcomes, will provide the necessary practice-based evidence needed to inform future allocation of resources to support healthy living among cancer survivors.Trial Registration: Australian and New Zealand Clinical Trials Registry (ANZCTR)--ACTRN12615000882527 (registered on 24/08/2015). [ABSTRACT FROM AUTHOR]- Published
- 2015
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21. Predictors of physical activity at 12 month follow-up after a supervised exercise intervention in postmenopausal women.
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Aparicio-Ting, Fabiola E., Farris, Megan, Courneya, Kerry S., Schiller, Ashley, and Friedenreich, Christine M.
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BREAST tumor prevention ,BODY composition ,AEROBIC exercises ,BIOMARKERS ,CARDIOPULMONARY system ,CLINICAL trials ,COMPUTED tomography ,CONFIDENCE intervals ,EXERCISE tests ,FISHER exact test ,FORECASTING ,HEALTH attitudes ,HEALTH behavior ,HEALTH promotion ,LONGITUDINAL method ,MULTIVARIATE analysis ,PROBABILITY theory ,QUESTIONNAIRES ,RECREATION ,RESEARCH evaluation ,RESEARCH funding ,STATISTICAL sampling ,SELF-efficacy ,SELF-evaluation ,STATISTICS ,T-test (Statistics) ,WOMEN'S health ,LOGISTIC regression analysis ,TREADMILLS ,BODY mass index ,RANDOMIZED controlled trials ,PLANNED behavior theory ,OXYGEN consumption ,POSTMENOPAUSE ,WAIST-hip ratio ,EXERCISE intensity ,DATA analysis software ,PHYSICAL activity ,DESCRIPTIVE statistics ,ABDOMINAL adipose tissue ,PHOTON absorptiometry ,ODDS ratio ,PSYCHOLOGY - Abstract
Background: Few studies have examined recreational physical activity (RPA) after participating in a structured exercise intervention. More specifically, little is known about the long-term effects of exercise interventions in post-menopausal women. This study had two objectives: 1) To compare RPA in postmenopausal women in the exercise group and the control group 12 months after the end of the Alberta Physical Activity and Breast Cancer Prevention (ALPHA) Trial; and 2) To apply the Theory of Planned Behaviour (TPB) to identify predictors of RPA 12 months post-intervention among women in the exercise group. Methods: Self-reported RPA 12-months post-intervention from a validated questionnaire was used to estimate RPA levels for control group (118/160, 74% response) and exercise group participants (126/160, 79% response). Bivariate analysis was used to compare RPA between exercise and control group participants and to identify TPB variables for multivariate analysis. Logistic regression was applied to TPB data collected from self- administered questionnaires at end of trial by exercise group participants (126/160, 79% response) to identify predictors of long-term RPA. Results: At 12 months post-intervention, 62% of women in the exercise group were active compared to 58% of controls (p = 0.52). Of the TPB constructs examined, self-efficacy (OR =2.98 (1.08-8.20)) and behavioural beliefs (OR = 1.46 (1.03-2.06)) were identified as predictors of RPA for exercise group participants. Conclusions: Levels of RPA in the exercise and control groups were comparable 12 months post intervention, indicating that participation in the ALPHA trial was associated with increased physical activity in previously inactive women, regardless of randomization into either the exercise group or in the control group. Exercise interventions that promote self-efficacy and positive behavioural beliefs have the potential to have long-term impacts on physical activity behaviour, although further research is needed to examine additional psychological, social and environmental predictors of long-term RPA in post-menopausal women. Trial registration: ClinicalTrials.gov NCT00522262. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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22. Study design and methods for the Breast Cancer and Exercise Trial in Alberta (BETA).
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Friedenreich, Christine M., MacLaughlin, Sarah, Neilson, Heather K., Stanczyk, Frank Z., Yutaka Yasui, Duha, Aalo, Lynch, Brigid M., Kallal, Ciara, and Courneya, Kerry S.
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BREAST cancer diagnosis ,BREAST cancer risk factors ,BREAST cancer treatment ,PHYSICAL activity ,CLINICAL trials ,FOLLOW-up studies (Medicine) - Abstract
Background Exercise has favorable effects on biomarkers associated with a lower risk of breast cancer, however it is unclear if higher doses of exercise provide additional effects. No clinical trial has systematically examined how different exercise volumes influence the mechanisms underlying breast cancer etiology. The Breast Cancer and Exercise Trial in Alberta (BETA) - a follow-up study to the Alberta Physical Activity and Breast Cancer Prevention (ALPHA) Trial - is examining how a one-year, high versus moderate volume aerobic exercise intervention influences several biomechanisms hypothesized to influence breast cancer risk in a group of postmenopausal women. Secondary aims are to compare intervention effects on psychosocial and quality of life outcomes as well as understand exercise adherence at 12 and 24 months, and maintenance of all study outcomes at 24 months. Methods/Design The BETA Trial is a two-center, two-armed randomized controlled exercise intervention trial conducted in 400 previously inactive, postmenopausal women aged 50-74 years, in Alberta, Canada. Participants were randomly assigned to a one-year aerobic exercise intervention of either high volume (300 minutes/week) or moderate volume (150 minutes/week). Blood draws and accelerometry were performed at baseline, six and 12 months. Baseline and 12- month measurements were taken of adiposity (including dual energy X-ray absorptiometry and computed tomography scans), physical fitness, dietary intake, self-reported physical activity and sedentary behavior, quality of life, perceived stress, happiness, sleep, and determinants of exercise adherence. Exercise maintenance was assessed and all study measurements were repeated at 24 months. Blood will be analyzed for endogenous estrogens, insulin resistance indicators, and inflammatory markers. Discussion The BETA Trial will compare the impact of a high versus moderate volume of aerobic exercise on a variety of biological, physiological, and psychological outcomes of relevance to postmenopausal women. A tightly controlled exercise intervention and objective outcome measurements are methodological strengths. The BETA Trial will inform future prevention initiatives by assessing adherence to a high volume of exercise over 12 months by postmenopausal women, and the ability of these women to maintain activity over the longer- term. The ultimate objective is to inform public health guidelines for reducing breast cancer risk through physical activity. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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23. Home-based functional walking program for advanced cancer patients receiving palliative care: a case series.
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Lowe, Sonya S., Watanabe, Sharon M., Baracos, Vickie E., and Courneya, Kerry S.
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ACCELEROMETERS ,CANCER patients ,CLINICAL trials ,GRIP strength ,RESEARCH methodology ,PALLIATIVE treatment ,QUESTIONNAIRES ,RESEARCH funding ,WALKING ,PILOT projects ,PRE-tests & post-tests ,DESCRIPTIVE statistics - Abstract
Background: Although meta-analyses have demonstrated that physical activity can positively impact quality of life outcomes in early stage cancer patients, it is not yet known whether these benefits can be extended to patients with advanced cancer. In a previous pilot survey of patients with advanced cancer with a median survival of 104 days, participants felt willing and able to participate in a physical activity intervention, and reported a strong preference for walking and home-based programming. Here, we report on the initial development and feasibility of a home-based functional walking program in patients with advanced cancer receiving palliative care. Methods: Nine adult patients were recruited from outpatient palliative care clinics and palliative home care. A pilot intervention trial was conducted over a 6-week period. The McGill Quality of Life Questionnaire (MQOL), Late Life Function and Disability Instrument (LLFDI), Edmonton Symptom Assessment System (ESAS), Seniors Fitness Test, four-test balance scale, and grip strength, were performed pre- and post-intervention. Participants wore activPAL™ accelerometers to monitor ambulatory activity levels. Results: Of the nine recruited participants, three participants dropped out prior to baseline testing due to hospital admission and feeling overwhelmed, and three participants dropped out during the intervention due to severe symptoms. Only three participants completed the intervention program, pre- and post-intervention assessments: two reported improvements in total MQOL scores, yet all three shared an overall trend towards worsening symptom and total fatigue scores post-intervention. Two participants passed away within 90 days of completing the intervention. Conclusions: This case series demonstrates the challenges of a physical activity intervention in patients with advanced cancer receiving palliative care. Further feasibility research is required in this patient population. Trial registration: This study is registered under ClinicalTrials.gov as NCT00438620. [ABSTRACT FROM AUTHOR]
- Published
- 2013
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24. The Alberta moving beyond breast cancer (AMBER) cohort study: a prospective study of physical activity and health-related fitness in breast cancer survivors.
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Courneya, Kerry S., Vallance, Jeff K., Culos-Reed, S. Nicole, McNeely, Margaret L., Bell, Gordon J., Mackey, John R., Yasui, Yutaka, Yuan, Yan, Matthews, Charles E., Lau, David CW, Cook, Diane, and Friedenreich, Christine M.
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BREAST cancer , *PHYSICAL activity , *CANCER patients , *PHYSICAL fitness , *LYMPHEDEMA , *MENTAL depression - Abstract
Background: Limited research has examined the association between physical activity, health-related fitness, and disease outcomes in breast cancer survivors. Here, we present the rationale and design of the Alberta Moving Beyond Breast Cancer (AMBER) Study, a prospective cohort study designed specifically to examine the role of physical activity and health-related fitness in breast cancer survivorship from the time of diagnosis and for the balance of life. The AMBER Study will examine the role of physical activity and health-related fitness in facilitating treatment completion, alleviating treatment side effects, hastening recovery after treatments, improving long term quality of life, and reducing the risks of disease recurrence, other chronic diseases, and premature death. Methods/Design: The AMBER Study will enroll 1500 newly diagnosed, incident, stage I-IIIc breast cancer survivors in Alberta, Canada over a 5 year period. Assessments will be made at baseline (within 90 days of surgery), 1 year, and 3 years consisting of objective and self-reported measurements of physical activity, health-related fitness, blood collection, lymphedema, patient-reported outcomes, and determinants of physical activity. A final assessment at 5 years will measure patient-reported data only. The cohort members will be followed for an additional 5 years for disease outcomes. Discussion: The AMBER cohort will answer key questions related to physical activity and health-related fitness in breast cancer survivors including: (1) the independent and interactive associations of physical activity and health-related fitness with disease outcomes (e.g., recurrence, breast cancer-specific mortality, overall survival), treatment completion rates, symptoms and side effects (e.g., pain, lymphedema, fatigue, neuropathy), quality of life, and psychosocial functioning (e.g., anxiety, depression, self-esteem, happiness), (2) the determinants of physical activity and health-related fitness including demographic, medical, social cognitive, and environmental variables, (3) the mediators of any observed associations between physical activity, health-related fitness, and health outcomes including biological, functional, and psychosocial, and (4) the moderators of any observed associations including demographic, medical, and biological/disease factors. Taken together, these data will provide a comprehensive inquiry into the outcomes, determinants, mechanisms, and moderators of physical activity and health-related fitness in breast cancer survivors. [ABSTRACT FROM AUTHOR]
- Published
- 2012
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25. Correlates of physical activity in a population-based sample of kidney cancer survivors: an application of the theory of planned behavior.
- Author
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Trinh, Linda, Plotnikoff, Ronald C., Rhodes, Ryan E., North, Scott, and Courneya, Kerry S.
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CANCER patients ,CHI-squared test ,CONFIDENCE intervals ,STATISTICAL correlation ,EPIDEMIOLOGY ,KIDNEY tumors ,MULTIVARIATE analysis ,QUESTIONNAIRES ,RESEARCH funding ,SCALE analysis (Psychology) ,DATA analysis ,STRUCTURAL equation modeling ,PLANNED behavior theory ,PHYSICAL activity - Abstract
Background: Over half of kidney cancer survivors (KCS) are completely inactive and only a quarter are meeting physical activity (PA) guidelines. This highlights the need to identify and understand the determinants of PA in this understudied population. The purpose of this study is to determine the social cognitive correlates of PA intention and behavior in KCS using the Theory of Planned Behavior (TPB). Methods: All 1,985 KCS diagnosed between 1996 and 2010 in Alberta, Canada were mailed a self-report survey that consisted of the Godin Leisure Time Exercise Questionnaire and standard TPB items for intention, planning, perceived behavioral control (PBC), affective and instrumental attitudes, and descriptive and injunctive norms. Standard demographic and medical variables were also collected. Results: Completed surveys were received from 703 of 1,654 (43%) eligible KCS. The TPB was tested using structural equation modelling and demonstrated an adequate-to-good fit to the data [χ
2 ² = 256.88, p < .001; TLI = 0.97; CFI = 0.98; RMSEA = 0.06, 90% CI = 0.05-0.06]. There were significant pathways to PA from PBC (β = 0.18, p = 0.02), planning (ß = 0.22, p < 0.01), and intention (β = 0.31, p < 0.01); and to planning from intention (β = 0.81, p < 0.01). In addition, there were significant model pathways to intention from instrumental attitude (β = 0.28, p = 0.03), descriptive norm (β = 0.09, p = 0.01), and PBC (β = 0.52, p < 0.01). Overall, the TPB accounted for 69%, 63%, and 42% of the variance in intention, planning and PA, respectively. Conclusion: The TPB appears to be a useful model for explaining PA in KCS. All TPB constructs except injunctive norm and affective attitude were useful for explaining intention with PBC emerging as the largest correlate. Developing PA interventions based on the TPB may be effective in promoting PA in KCS and may lead to important improvements in health. [ABSTRACT FROM AUTHOR]- Published
- 2012
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26. Efficacy of a referral and physical activity program for survivors of prostate cancer [ENGAGE]: Rationale and design for a cluster randomised controlled trial.
- Author
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Livingston, Patricia M., Salmon, Jo, Courneya, Kerry S., Gaskin, Cadeyrn J., Craike, Melinda, Botti, Mari, Broadbent, Suzanne, and Kent, Bridie
- Subjects
PROSTATE cancer patients ,PHYSICAL activity ,EXERCISE ,QUALITY of life ,CANCER in men - Abstract
Background: Despite evidence that physical activity improves the health and well-being of prostate cancer survivors, many men do not engage in sufficient levels of activity. The primary aim of this study (ENGAGE) is to determine the efficacy of a referral and physical activity program among survivors of prostate cancer, in terms of increasing participation in physical activity. Secondary aims are to determine the effects of the physical activity program on psychological well-being, quality of life and objective physical functioning. The influence of individual and environmental mediators on participation in physical activity will also be determined. Methods/Design: This study is a cluster randomised controlled trial. Clinicians of prostate cancer survivors will be randomised into either the intervention or control condition. Clinicians in the intervention condition will refer eligible patients (n = 110) to participate in an exercise program, comprising 12 weeks of supervised exercise sessions and unsupervised physical activity. Clinicians allocated to the control condition will provide usual care to eligible patients (n = 110), which does not involve the recommendation of the physical activity program. Participants will be assessed at baseline, 12 weeks, 6 months, and 12 months on physical activity, quality of life, anxiety, depression, self-efficacy, outcome expectations, goals, and socio-structural factors. Discussion: The findings of this study have implications for clinicians and patients with different cancer types or other chronic health conditions. It will contribute to our understanding on the potential impact of clinicians promoting physical activity to patients and the long term health benefits of participating in physical activity programs. [ABSTRACT FROM AUTHOR]
- Published
- 2011
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27. Efficacy, effectiveness, and behavior change trials in exercise research.
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Courneya, Kerry S.
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- *
HEALTH behavior , *PHYSICAL fitness , *EXERCISE , *BEHAVIOR modification - Abstract
Background: The widespread incorporation of behavioral support interventions into exercise trials has sometimes caused confusion concerning the primary purpose of a trial. The purpose of the present paper is to offer some conceptual and methodological distinctions among three types of exercise trials with a view towards improving their design, conduct, reporting, and interpretation. Discussion: Exercise trials can be divided into "health outcome trials" or "behavior change trials" based on their primary outcome. Health outcome trials can be further divided into efficacy and effectiveness trials based on their potential for dissemination into practice. Exercise efficacy trials may achieve high levels of exercise adherence by supervising the exercise over a short intervention period ("traditional" exercise efficacy trials) or by the adoption of an extensive behavioral support intervention designed to accommodate unsupervised exercise and/or an extended intervention period ("contemporary" exercise efficacy trials). Exercise effectiveness trials may emanate from the desire to test exercise interventions with proven efficacy ("traditional" exercise effectiveness trials) or the desire to test behavioral support interventions with proven feasibility ("contemporary" exercise effectiveness trials). Efficacy, effectiveness, and behavior change trials often differ in terms of their primary and secondary outcomes, theoretical models adopted, selection of participants, nature of the exercise and comparison interventions, nature of the behavioral support intervention, sample size calculation, and interpretation of trial results. Summary: Exercise researchers are encouraged to clarify the primary purpose of their trial to facilitate its design, conduct, and interpretation. [ABSTRACT FROM AUTHOR]
- Published
- 2010
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28. Alberta Diabetes and Physical Activity Trial (ADAPT): A randomized theory-based efficacy trial for adults with type 2 diabetes - rationale, design, recruitment, evaluation, and dissemination.
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Plotnikoff, Ronald C., Courneya, Kerry S., Sigal, Ronald J., Johnson, Jeffrey A., Birkett, Nicholas, Lau, David, Raine, Kim, Johnson, Steven T., and Karunamuni, Nandini
- Subjects
- *
RANDOMIZED controlled trials , *DIABETES , *PHYSICAL activity , *HOTLINES (Counseling) , *QUESTIONNAIRES , *TEACHING aids , *PEDOMETERS , *LOGBOOKS - Abstract
Background: The primary aim of this study was to compare the efficacy of three physical activity (PA) behavioural intervention strategies in a sample of adults with type 2 diabetes. Method/Design: Participants (N = 287) were randomly assigned to one of three groups consisting of the following intervention strategies: (1) standard printed PA educational materials provided by the Canadian Diabetes Association [i.e., Group 1/control group)]; (2) standard printed PA educational materials as in Group 1, pedometers, a log book and printed PA information matched to individuals' PA stage of readiness provided every 3 months (i.e., Group 2); and (3) PA telephone counseling protocol matched to PA stage of readiness and tailored to personal characteristics, in addition to the materials provided in Groups 1 and 2 (i.e., Group 3). PA behaviour measured by the Godin Leisure Time Exercise Questionnaire and related social-cognitive measures were assessed at baseline, 3, 6, 9, 12 and 18-months (i.e., 6-month follow-up). Clinical (biomarkers) and health-related quality of life assessments were conducted at baseline, 12-months, and 18-months. Linear Mixed Model (LMM) analyses will be used to examine time-dependent changes from baseline across study time points for Groups 2 and 3 relative to Group 1. Discussion: ADAPT will determine whether tailored but low-cost interventions can lead to sustainable increases in PA behaviours. The results may have implications for practitioners in designing and implementing theory-based physical activity promotion programs for this population. Clinical Trials Registration: ClinicalTrials.gov identifier: NCT00221234 [ABSTRACT FROM AUTHOR]
- Published
- 2010
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29. A test of cognitive mediation in a 12-month physical activity workplace intervention: does it explain behaviour change in women?
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Plotnikoff, Ronald C., Pickering, Michael A., Rhodes, Ryan E., Courneya, Kerry S., and Spence, John C.
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PHYSICAL activity ,THEORY ,ORGANIZATIONAL behavior ,LEISURE ,RANDOMIZED controlled trials - Abstract
Background: Attempts to demonstrate the efficacy of interventions aimed at increasing physical activity (PA) have been mixed. Further, studies are seldom designed in a manner that facilitates the understanding of how or why a treatment is effective or ineffective and PA intervention designs should be guided by a heavier reliance upon behavioral theory. The use of a mediating variable framework offers a systematic methodological approach to testing the role of theory, and could also identify the effectiveness of specific intervention components. The primary purpose of this paper was to test the mediating role that cognitive constructs may have played in regards to the positive effect that a workplace behavioral intervention had on leisure-time PA for women. A subsidiary purpose was to examine the cross-sectional relationships of these cognitive constructs with PA behavior. Methods: The Physical Activity Workplace Study was a randomized controlled trial which compared the effects of stage-matched and standard print materials upon self-reported leisure-time PA, within a workplace sample at 6 and 12-months. In this secondary analysis we examined the mediation effects of 14 psychosocial constructs across 3 major social-cognitive theories which were operationalized for the intervention materials and measured at baseline, 6 and 12-months. We examined change in PA and change in the psychological constructs employing a mediation strategy proposed by Baron and Kenny for: (1) the first 6-months (i.e., initial change), (2) the second 6-months (i.e., delayed change), and (3) the entire 12-months (overall change) of the study on 323 women (n = 213 control/standard materials group; n = 110 stage-matched materials group). Results: Of the 14 constructs and 42 tests (including initial, delayed and overall change) two positive results were identified (i.e., overall change in pros, initial change in experiential powerful intervention approaches processes), with very small effect sizes. However, these mediating results were eliminated after adjusting for the multiple statistical tests. Conclusions: The intervention did not change these mediators in any substantive way, and show a similar pattern to prior research where interventions generally do not result in a change in mediation of behavior change. It is important to report mediation results in randomized controlled trials whether the findings are null or positive. Future studies may wish to focus on more detailed dose-response issues between mediators and behavior, the inclusion of moderators that could affect individual change, or different mediator constructs at higher levels of measurement specificity. Continued work on innovative and more powerful PA intervention approaches are needed. [ABSTRACT FROM AUTHOR]
- Published
- 2010
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30. A randomized trial of a lifestyle intervention in obese endometrial cancer survivors: quality of life outcomes and mediators of behavior change.
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von Gruenigen, Vivian E., Gibbons, Heidi E., Kavanagh, Mary Beth, Janata, Jeffrey W., Lerner, Edith, and Courneya, Kerry S.
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OVERWEIGHT persons ,QUALITY of life ,BEHAVIOR modification ,MENTAL depression ,SELF-efficacy ,WEIGHT loss - Abstract
Background: To examine the effects of a 6 month lifestyle intervention on quality of life, depression, self-efficacy and eating behavior changes in overweight and obese endometrial cancer survivors. Methods: Early stage endometrial cancer survivors were randomized to intervention (n = 23) or usual care (n = 22) groups. Chi-square, Student's t-test and repeated measures analysis of variance were used in intent-to-treat analyses. Outcomes were also examined according to weight loss. Results: Morbidly obese patients had significantly lower self-efficacy, specifically when feeling physical discomfort. There was a significant improvement for self-efficacy related to social pressure (p = .03) and restraint (p = .02) in the LI group. There was a significant difference for emotional well-being quality of life (p = .02), self-efficacy related to negative emotions (p < .01), food availability (p = .03), and physical discomfort (p = .01) in women who lost weight as compared to women who gained weight. Improvement in restraint was also reported in women who lost weight (p < .01). Conclusion: This pilot lifestyle intervention had no effect on quality of life or depression but did improve self-efficacy and some eating behaviors. [ABSTRACT FROM AUTHOR]
- Published
- 2009
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31. Diabetes NetPLAY: A physical activity website and linked email counselling randomized intervention for individuals with type 2 diabetes.
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Liebreich, Tanis, Plotnikoff, Ronald C., Courneya, Kerry S., and Boulé, Normand
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INTERNET counseling ,DIABETES ,SOCIAL cognition theory (Communication) ,INSULIN resistance ,EMAIL ,COMPUTER network resources - Abstract
Background -: This pilot study evaluated the feasibility (recruitment, retention, adherence and satisfaction) and preliminary efficacy of a 12-week website and email-linked counselling intervention on physical activity behaviour change in individuals with type 2 diabetes. Methods -: A total of 49 individuals with type 2 diabetes (59% female, average age 54.1 years) were randomized to the Diabetes NetPLAY intervention or control condition. The intervention condition received information grounded in the Social Cognitive Theory (SCT), personalized weekly emails, an on-line logbook and message board. Key outcomes included physical activity behaviour and related cognition changes. The control condition was provided links to the Canadian Diabetes Association's Clinical Practice Guidelines for Physical Activity and Canada's Guide to Physical Activity. Results -: Intervention participants indicated high levels of satisfaction for this mode of delivery and study results demonstrated the feasibility of web-based mediums for the delivery of physical activity information in this population. The intervention group demonstrated a significant improvement in total vigorous and moderate minutes of physical activity (p = 0.05) compared to the control group over the 12-week study. Among the SCT variables, behavioural capacity, showed a significant increase (p < 0.001) among intervention participants. Conclusion -: Web-based interventions for individuals with type 2 diabetes are feasible and show promise for improving positive physical activity outcomes. [ABSTRACT FROM AUTHOR]
- Published
- 2009
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32. Lifestyle behaviors, obesity, and perceived health among men with and without a diagnosis of prostate cancer: a population-based, cross-sectional study.
- Author
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Rogers, Laura Q., Courneya, Kerry S., Paragi-Gururaja, Rammarayan, Markwell, Stephen J., and Imeokparia, Remi
- Subjects
- *
CROSS-sectional method , *OBESITY , *PROSTATE cancer , *CANCER patients , *NUTRITION disorders - Abstract
Background: A better understanding of how prostate cancer survivors differ from men without prostate cancer and whether these potential differences vary across demographic subgroups will help to focus and prioritize future public health interventions for improving the health and well-being of prostate cancer survivors. Therefore, our study aims were to compare lifestyle behaviors, body mass index (BMI), and perceived health in men with and without a diagnosis of prostate cancer in a national, population-based sample and to explore whether these comparisons differ for demographic subgroups. Methods: In a cross-sectional study, men aged ≥ 40 were identified from the Behavioral Risk Factor Surveillance System (BRFSS) 2002 data (n = 63,662). Respondents reporting history of prostate cancer (n = 2,524) were compared with non prostate cancer controls (n = 61,138) with regard to daily fruit and vegetable servings (FVPD), smoking, alcohol, sedentary behavior, BMI, and perceived health. Multivariable logistic regression calculated adjusted odds ratios (OR) and 95% confidence intervals (CI) for the entire sample and for age, race, education, and urbanicity subgroups. Results: Men with prostate cancer did not differ from men without prostate cancer with regard to smoking, alcohol, sedentary behavior, and obesity but were more likely to consume ≥ 5 FVPD (OR, 95% CI: 1.30, 1.09-1.56) and report poor or fair health (OR, 95% CI: 1.62, 1.33-1.97). Subgroup analyses demonstrated attenuation of the higher likelihood of ≥ 5 FVPD among prostate cancer survivors in rural respondents (OR, 95% CI: 0.98, 0.72-1.33). Poorer perceived health was greatest if ≤ 65 years of age (OR, 95% CI: 2.54, 1.79-3.60) and nonsignificant if black (OR, 95% CI: 1.41, 0.70-2.82). Smoking and alcohol which were not significant for the sample as a whole, demonstrated significant associations in certain subgroups. Conclusion: Although efforts to enhance perceived health and healthy lifestyle behaviors among prostate cancer survivors are warranted, demographic subgroups such as prostate cancer survivors ≤ 65 and rural populations may require more aggressive interventions. [ABSTRACT FROM AUTHOR]
- Published
- 2008
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33. Prediction of leisure-time walking: an integration of social cognitive, perceived environmental, and personality factors.
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Rhodes, Ryan E., Courneya, Kerry S., Blanchard, Chris M., and Plotnikoff, Ronald C.
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- *
WALKING , *HEALTH behavior , *PERSONALITY , *HEALTH planning , *ATTITUDE (Psychology) , *POPULATION - Abstract
Background: Walking is the primary focus of population-based physical activity initiatives but a theoretical understanding of this behaviour is still elusive. The purpose of this study was to integrate personality, the perceived environment, and planning into a theory of planned behaviour (TPB) framework to predict leisure-time walking. Methods: Participants were a random sample (N = 358) of Canadian adults who completed measures of the TPB, planning, perceived neighbourhood environment, and personality at Time 1 and self-reported walking behaviour two months later. Results: Analyses using structural equation modelling provided evidence that leisure-time walking is largely predicted by intention (standardized effect = .42) with an additional independent contribution from proximity to neighbourhood retail shops (standardized effect = .18). Intention, in turn, was predicted by attitudes toward walking and perceived behavioural control. Effects of perceived neighbourhood aesthetics and walking infrastructure on walking were mediated through attitudes and intention. Moderated regression analysis showed that the intention-walking relationship was moderated by conscientiousness and proximity to neighbourhood recreation facilities but not planning. Conclusion: Overall, walking behaviour is theoretically complex but may best be addressed at a population level by facilitating strong intentions in a receptive environment even though individual differences may persist. [ABSTRACT FROM AUTHOR]
- Published
- 2007
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34. Correlates of exercise motivation and behavior in a population-based sample of endometrial cancer survivors: an application of the Theory of Planned Behavior.
- Author
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Karvinen, Kristina H., Courneya, Kerry S., Campbell, Kristin L., Pearcey, Robert G., Dundas, George, Capstick, Valerie, and Tonkin, Katia S.
- Subjects
- *
HEALTH surveys , *CANCER patients , *MOTIVATION (Psychology) , *EXERCISE , *HEALTH behavior , *SOCIAL factors - Abstract
Background: Despite evidence of the benefits of exercise in cancer survivors, exercise participation rates end to decline after treatments. Few studies have examined the determinants of exercise in less common cancer sites. In this study, we examined medical, demographic, and social cognitive correlates of exercise in endometrial cancer survivors using the Theory of Planned Behavior (TPB). Methods: A mailed survey was completed by 354 endometrial cancer survivors (1 to 10 years postdiagnosis) residing in Alberta, Canada. The study was cross-sectional. Exercise behavior was assessed using the Godin Leisure Time Exercise Questionnaire and the TPB constructs were assessed with standard self-report scales. Multiple regression analyses were used to determine the independent associations of the TPB constructs with intention and behavior. Results: Chi-square analyses indicated that marital status (p = .003), income level (p = .013), and body mass index (BMI) (p = .020) were associated with exercise. The TPB explained 34.1% of the variance in exercise behavior with intention (β = .38, p < .001) and self-efficacy (β = .18, p = .029) being independent correlates. For intention, 38.3% of the variance was explained by the TPB with self-efficacy (β = .34, p < .001) and affective attitude (β = .30, p < .001) being the independent correlates. The TPB mediated the associations of marital status and BMI with exercise but not income level. Age and BMI moderated the associations of the TPB with intention and behavior. Conclusion: The TPB may be a useful framework for understanding exercise in endometrial cancer survivors. Exercise behavior change interventions based on the TPB should be tested in this growing population. [ABSTRACT FROM AUTHOR]
- Published
- 2007
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35. Peer support for the maintenance of physical activity and health in cancer survivors: the PEER trial - a study protocol of a randomised controlled trial
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Adlard, Kirsten N., Jenkins, David G., Salisbury, Chloe E., Bolam, Kate A., Gomersall, Sjaan R., Aitken, Joanne F., Chambers, Suzanne K., Dunn, Jeff C., Courneya, Kerry S., Skinner, Tina L., Adlard, Kirsten N., Jenkins, David G., Salisbury, Chloe E., Bolam, Kate A., Gomersall, Sjaan R., Aitken, Joanne F., Chambers, Suzanne K., Dunn, Jeff C., Courneya, Kerry S., and Skinner, Tina L.
- Abstract
Adlard, K. N., Jenkins, D. G., Salisbury, C. E., Bolam, K. A., Gomersall, S. R., Aitken, J. F., ... Skinner, T. L. (2019). Peer support for the maintenance of physical activity and health in cancer survivors: the PEER trial-a study protocol of a randomised controlled trial. BMC Cancer, 19, Article 656. Available here
36. Perceived benefits and barriers to exercise for recently treated patients with multiple myeloma: a qualitative study.
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Craike, Melinda J, Hose, Kaye, Courneya, Kerry S, Harrison, Simon J, and Livingston, Patricia M
- Abstract
Background: Understanding the physical activity experiences of patients with multiple myeloma (MM) is essential to inform the development of evidence-based interventions and to quantify the benefits of physical activity. The aim of this study was to gain an in-depth understanding of the physical activity experiences and perceived benefits and barriers to physical activity for patients with MM.Methods: This was a qualitative study that used a grounded theory approach. Semi-structured interviews were conducted in Victoria, Australia by telephone from December 2011-February 2012 with patients who had been treated for MM within the preceding 2-12 months. Interviews were transcribed and analysed using the constant comparison coding method to reduce the data to themes. Gender differences and differences between treatment groups were explored.Results: Twenty-four interviews were completed. The sample comprised 13 females (54%), with a mean age of 62 years (SD = 8.8). Sixteen (67%) participants had received an autologous stem cell transplant (ASCT). All participants currently engaged in a range of light to moderate intensity physical activity; walking and gardening were the most common activities. Recovery from the symptoms of MM and side effects of therapy, psychological benefits, social factors and enjoyment were important benefits of physical activity. Barriers to physical activity predominately related to the symptoms of MM and side effects of therapy, including pain, fatigue, and fear of infection. Low self- motivation was also a barrier. Women participated in a more diverse range of physical activities than men and there were gender differences in preferred type of physical activity. Women were more likely to report psychological and social benefits; whereas men reported physical activity as a way to keep busy and self-motivation was a barrier. Patients treated with an ASCT more often reported affective benefits of participation in physical activity and fatigue as a barrier. Patients treated with other therapies (e.g., chemotherapy, radiotherapy) were more likely to report pain as a barrier.Conclusions: Patients with MM experience debilitating effects of their condition and therapy, which influences their level and intensity of physical activity participation. Physical activity programs should be individualised; take into consideration gender differences and the impact of different types of therapy on physical activity; and focus on meeting the psychological, coping and recovery needs of patients. [ABSTRACT FROM AUTHOR]- Published
- 2013
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37. Predictors of adherence to different types and doses of supervised exercise during breast cancer chemotherapy.
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Courneya KS, Segal RJ, Gelmon K, Mackey JR, Friedenreich CM, Yasui Y, Reid RD, Proulx C, Trinh L, Dolan LB, Wooding E, Vallerand JR, and McKenzie DC
- Subjects
- Adult, Antineoplastic Combined Chemotherapy Protocols, Body Mass Index, Canada, Exercise Therapy methods, Female, Humans, Middle Aged, Multivariate Analysis, Prospective Studies, Quality of Life, Regression Analysis, Breast Neoplasms therapy, Exercise, Patient Compliance
- Abstract
Background: Exercise is beneficial for breast cancer patients during chemotherapy but adherence to different types and doses of exercise is a challenge. The purpose of this study was to examine predictors of adherence to different types and doses of exercise during breast cancer chemotherapy in a multicenter randomized controlled trial., Methods: Breast cancer patients in Edmonton, Vancouver, and Ottawa, Canada receiving chemotherapy (N = 301) were randomized to a standard dose of 25-30 minutes of aerobic exercise (STAN), a higher dose of 50-60 minutes of aerobic exercise (HIGH), or a higher dose of 50-60 minutes of combined aerobic and resistance exercise (COMB). Predictors included demographic, medical, fitness, and quality of life variables. Exercise adherence was measured as the percentage of supervised exercise sessions completed., Results: Overall adherence to the supervised exercise sessions was 73% (SD = 24%). In a multivariate regression model, six independent predictors explained 26.4% (p < 0.001) of the variance in exercise adherence. Higher exercise adherence was achieved by breast cancer patients in Vancouver (p < 0.001), with fewer endocrine symptoms (p = 0.009), randomized to STAN (p = 0.009), with fewer exercise limitations (p = 0.009), receiving shorter chemotherapy protocols (p = 0.015), and with higher VO2peak (p = 0.017). Disease stage (p for interaction = 0.015) and body mass index (p for interaction = 0.030) interacted with group assignment to predict adherence. For disease stage, patients with stage I/IIa disease adhered equally well to all three exercise interventions whereas patients with stage IIb/III disease adhered better to the STAN intervention than the two higher dose exercise interventions. For body mass index, healthy weight patients adhered equally well to all three exercise interventions whereas overweight patients adhered best to STAN and worst to COMB; and obese patients adhered best to STAN and worst to HIGH., Conclusions: Determinants of exercise adherence in breast cancer patients receiving chemotherapy are multidisciplinary and may vary by the exercise prescription.
- Published
- 2014
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38. Predicting OptimaL cAncer RehabIlitation and Supportive care (POLARIS): rationale and design for meta-analyses of individual patient data of randomized controlled trials that evaluate the effect of physical activity and psychosocial interventions on health-related quality of life in cancer survivors.
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Buffart LM, Kalter J, Chinapaw MJ, Heymans MW, Aaronson NK, Courneya KS, Jacobsen PB, Newton RU, Verdonck-de Leeuw IM, and Brug J
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- Humans, Motor Activity, Quality of Life, Randomized Controlled Trials as Topic, Stress, Psychological therapy, Survivors psychology, Data Collection methods, Meta-Analysis as Topic, Neoplasms psychology, Neoplasms rehabilitation, Research Design
- Abstract
Background: Effective interventions to improve quality of life of cancer survivors are essential. Numerous randomized controlled trials have evaluated the effects of physical activity or psychosocial interventions on health-related quality of life of cancer survivors, with generally small sample sizes and modest effects. Better targeted interventions may result in larger effects. To realize such targeted interventions, we must determine which interventions that are presently available work for which patients, and what the underlying mechanisms are (that is, the moderators and mediators of physical activity and psychosocial interventions). Individual patient data meta-analysis has been described as the 'gold standard' of systematic review methodology. Instead of extracting aggregate data from study reports or from authors, the original research data are sought directly from the investigators. Individual patient data meta-analyses allow for adequate statistical analysis of intervention effects and moderators of such effects.Here, we report the rationale and design of the Predicting OptimaL cAncer RehabIlitation and Supportive care (POLARIS) Consortium. The primary aim of POLARIS is 1) to conduct meta-analyses based on individual patient data to evaluate the effect of physical activity and psychosocial interventions on the health-related quality of life of cancer survivors; 2) to identify important demographic, clinical, personal, or intervention-related moderators of the effect; and 3) to build and validate clinical prediction models identifying the most relevant predictors of intervention success., Methods/design: We will invite investigators of randomized controlled trials that evaluate the effects of physical activity and/or psychosocial interventions on health-related quality of life compared with a wait-list, usual care or attention control group among adult cancer survivors to join the POLARIS consortium and share their data for use in pooled analyses that will address the proposed aims. We are in the process of identifying eligible randomized controlled trials through literature searches in four databases. To date, we have identified 132 eligible and unique trials., Discussion: The POLARIS consortium will conduct the first individual patient data meta-analyses in order to generate evidence essential to targeting physical activity and psychosocial programs to the individual survivor's characteristics, capabilities, and preferences., Registration Prospero: International prospective register of systematic reviews, CRD42013003805.
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- 2013
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39. A randomized controlled trial on the effectiveness of strength training on clinical and muscle cellular outcomes in patients with prostate cancer during androgen deprivation therapy: rationale and design.
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Thorsen L, Nilsen TS, Raastad T, Courneya KS, Skovlund E, and Fosså SD
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- Body Composition physiology, Combined Modality Therapy adverse effects, Combined Modality Therapy methods, Exercise Therapy methods, Fatigue, Feasibility Studies, Humans, Male, Muscle Strength physiology, Muscle, Skeletal anatomy & histology, Prostatic Neoplasms physiopathology, Prostatic Neoplasms psychology, Quality of Life, Androgen Antagonists therapeutic use, Muscle, Skeletal physiopathology, Prostatic Neoplasms therapy, Resistance Training methods
- Abstract
Background: Studies indicate that strength training has beneficial effects on clinical health outcomes in prostate cancer patients during androgen deprivation therapy. However, randomized controlled trials are needed to scientifically determine the effectiveness of strength training on the muscle cell level. Furthermore, close examination of the feasibility of a high-load strength training program is warranted. The Physical Exercise and Prostate Cancer (PEPC) trial is designed to determine the effectiveness of strength training on clinical and muscle cellular outcomes in non-metastatic prostate cancer patients after high-dose radiotherapy and during ongoing androgen deprivation therapy., Methods/design: Patients receiving androgen deprivation therapy for 9-36 months combined with external high-dose radiotherapy for locally advanced prostate cancer are randomized to an exercise intervention group that receives a 16 week high-load strength training program or a control group that is encouraged to maintain their habitual activity level. In both arms, androgen deprivation therapy is continued until the end of the intervention period.Clinical outcomes are body composition (lean body mass, bone mineral density and fat mass) measured by Dual-energy X-ray Absorptiometry, serological outcomes, physical functioning (muscle strength and cardio-respiratory fitness) assessed with physical tests and psycho-social functioning (mental health, fatigue and health-related quality of life) assessed by questionnaires. Muscle cellular outcomes are a) muscle fiber size b) regulators of muscle fiber size (number of myonuclei per muscle fiber, number of satellite cells per muscle fiber, number of satellite cells and myonuclei positive for androgen receptors and proteins involved in muscle protein degradation and muscle hypertrophy) and c) regulators of muscle fiber function such as proteins involved in cellular stress and mitochondrial function. Muscle cellular outcomes are measured on muscle cross sections and muscle homogenate from muscle biopsies obtained from muscle vastus lateralis., Discussion: The findings from the PEPC trial will provide new knowledge on the effects of high-load strength training on clinical and muscle cellular outcomes in prostate cancer patients during androgen deprivation therapy., Trial Registration: ClinicalTrials.gov: NCT00658229.
- Published
- 2012
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40. Determinants of quality of life in adults with type 1 and type 2 diabetes.
- Author
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Imayama I, Plotnikoff RC, Courneya KS, and Johnson JA
- Subjects
- Alberta, Female, Health Status Indicators, Humans, Life Style, Longitudinal Studies, Male, Middle Aged, Personal Satisfaction, Regression Analysis, Surveys and Questionnaires, Diabetes Mellitus, Type 1 physiopathology, Diabetes Mellitus, Type 1 psychology, Diabetes Mellitus, Type 2 physiopathology, Diabetes Mellitus, Type 2 psychology, Motor Activity, Quality of Life
- Abstract
Background: Limited evidence exists on the determinants of quality of life (QoL) specific to adults with type 1 diabetes (T1D). Further, it appears no study has compared the determinants of QoL between T1D and type 2 diabetes (T2D) groups. The objectives of this study were to examine: (1) determinants of QoL in adults with T1D; and, (2) differences in QoL determinants between T1D and T2D groups., Methods: The Alberta Longitudinal Exercise and Diabetes Research Advancement (ALEXANDRA) study, a longitudinal study of adults with diabetes in Alberta, Canada. Adults (18 years and older) with T1D (N = 490) and T2D (N = 1,147) provided information on demographics (gender, marital status, education, and annual income), personality (activity trait), medical factors (diabetes duration, insulin use, number of comorbidities, and body mass index), lifestyle behaviors (smoking habits, physical activity, and diet), health-related quality of life (HRQL) and life satisfaction. Multiple regression models identified determinants of HRQL and life satisfaction in adults with T1D. These determinants were compared with determinants for T2D adults reported in a previous study from this population data set. Factors significantly associated with HRQL and life satisfaction in either T1D or T2D groups were further tested for interaction with diabetes type., Results: In adults with T1D, higher activity trait (personality) score (β = 0.28, p < 0.01), fewer comorbidities (β = -0.27, p < 0.01), lower body mass index (BMI)(β = -0.12, p < 0.01), being a non-smoker (β = -0.14, p < 0.01), and higher physical activity levels (β = 0.16, p < 0.01) were associated with higher HRQL. Having a partner (β = 0.11, p < 0.05), high annual income (β = 0.16, p < 0.01), and high activity trait (personality) score (β = 0.27, p < 0.01) were significantly associated with higher life satisfaction. There was a significant age × diabetes type interaction for HRQL. The T2D group had a stronger positive relationship between advancing age and HRQL compared to the T1D group. No interaction was significant for life satisfaction., Conclusions: Health services should target medical and lifestyle factors and provide support for T1D adults to increase their QoL. Additional social support for socioeconomically disadvantaged individuals living with this disease may be warranted. Health practitioners should also be aware that age has different effects on QoL between T1D and T2D adults.
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- 2011
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41. A randomised controlled trial of a tele-based lifestyle intervention for colorectal cancer survivors ('CanChange'): study protocol.
- Author
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Hawkes AL, Pakenham KI, Courneya KS, Gollschewski S, Baade P, Gordon LG, Lynch BM, Aitken JF, and Chambers SK
- Subjects
- Female, Follow-Up Studies, Humans, Male, Prospective Studies, Research Design, Clinical Protocols, Colorectal Neoplasms psychology, Life Style, Survivors psychology
- Abstract
Background: Colorectal cancer survivors may suffer from a range of ongoing psychosocial and physical problems that negatively impact on quality of life. This paper presents the study protocol for a novel telephone-delivered intervention to improve lifestyle factors and health outcomes for colorectal cancer survivors., Methods/design: Approximately 350 recently diagnosed colorectal cancer survivors will be recruited through the Queensland Cancer Registry and randomised to the intervention or control condition. The intervention focuses on symptom management, lifestyle and psychosocial support to assist participants to make improvements in lifestyle factors (physical activity, healthy diet, weight management, and smoking cessation) and health outcomes. Participants will receive up to 11 telephone-delivered sessions over a 6 month period from a qualified health professional or 'health coach'. Data collection will occur at baseline (Time 1), post-intervention or six months follow-up (Time 2), and at 12 months follow-up for longer term effects (Time 3). Primary outcome measures will include physical activity, cancer-related fatigue and quality of life. A cost-effective analysis of the costs and outcomes for survivors in the intervention and control conditions will be conducted from the perspective of health care costs to the government., Discussion: The study will provide valuable information about an innovative intervention to improve lifestyle factors and health outcomes for colorectal cancer survivors., Trial Registration: ACTRN12608000399392.
- Published
- 2009
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42. Aerobic physical activity and resistance training: an application of the theory of planned behavior among adults with type 2 diabetes in a random, national sample of Canadians.
- Author
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Plotnikoff RC, Courneya KS, Trinh L, Karunamuni N, and Sigal RJ
- Abstract
Background: Aerobic physical activity (PA) and resistance training are paramount in the treatment and management of type 2 diabetes (T2D), but few studies have examined the determinants of both types of exercise in the same sample., Objective: The primary purpose was to investigate the utility of the Theory of Planned Behavior (TPB) in explaining aerobic PA and resistance training in a population sample of T2D adults., Methods: A total of 244 individuals were recruited through a random national sample which was created by generating a random list of household phone numbers. The list was proportionate to the actual number of household telephone numbers for each Canadian province (with the exception of Quebec). These individuals completed self-report TPB constructs of attitude, subjective norm, perceived behavioral control and intention, and a 3-month follow-up that assessed aerobic PA and resistance training., Results: TPB explained 10% and 8% of the variance respectively for aerobic PA and resistance training; and accounted for 39% and 45% of the variance respectively for aerobic PA and resistance training intentions., Conclusion: These results may guide the development of appropriate PA interventions for aerobic PA and resistance training based on the TPB.
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- 2008
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43. Understanding breast cancer patients' preference for two types of exercise training during chemotherapy in an unblinded randomized controlled trial.
- Author
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Courneya KS, Reid RD, Friedenreich CM, Gelmon K, Proulx C, Vallance JK, McKenzie DC, and Segal RJ
- Abstract
Background: Patient preference for group assignment may affect outcomes in unblinded trials but few studies have attempted to understand such preferences. The purpose of the present study was to examine factors associated with breast cancer patients' preference for two types of exercise training during chemotherapy., Methods: Breast cancer patients (N = 242) completed a battery of tests including a questionnaire that assessed patient preference and the theory of planned behavior (TPB) prior to being randomized to usual care, resistance exercise training (RET), or aerobic exercise training (AET)., Results: 99 (40.9%) participants preferred RET, 88 (36.4%) preferred AET, and 55 (22.7%) reported no preference. Past exercisers (p = 0.023), smokers (p = 0.004), and aerobically fitter participants (p = 0.005) were more likely to prefer RET. As hypothesized, participants that preferred AET had more favorable TPB beliefs about AET whereas participants that preferred RET had more favorable TPB beliefs about RET. In multivariate modeling, patient preference for RET versus AET was explained (R2 = .46; p < 0.001) by the difference in motivation for RET versus AET (beta = .56; p < 0.001), smoking status (beta = .13; p = 0.007), and aerobic fitness (beta = .12; p = 0.018). Motivational difference between RET versus AET, in turn, was explained (R2 = .48; p < 0.001) by differences in instrumental attitude (beta = .27; p < 0.001), affective attitude (beta = .25; p < 0.001), and perceived behavioral control (beta = .24; p < 0.001)., Conclusion: Breast cancer patients' preference for RET versus AET during chemotherapy was predicted largely by a difference in motivation for each type of exercise which, in turn, was based on differences in their beliefs about the anticipated benefits, enjoyment, and difficulty of performing each type of exercise during chemotherapy. These findings may help explain patient preference effects in unblinded behavioral trials., Trial Registration: ClinicalTrials.gov Identifier NCT00115713.
- Published
- 2008
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