1. Primena lab fermenta (himozina) u terapiji neonatalnih dijareja teladi
- Author
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Ninković, Milan, Zdravković, Nemanja, Žutić, Jadranka, Nikolić, Marko, Jezdimirović, Nemanja, Bojkovski, Jovan, Arsić, Sveta, Ninković, Milan, Zdravković, Nemanja, Žutić, Jadranka, Nikolić, Marko, Jezdimirović, Nemanja, Bojkovski, Jovan, and Arsić, Sveta
- Abstract
Neonatalne dijareje teladi predstavljaju veoma značajan problem koji u govedarskoj proizvodnji nanosi velike gubitke. Infektivna etiologija dijareja, pre svega virusa Corona i Rota, otvaraju vrata enteropatogenim bakterijama izazivajući atrofiju crevnih resica, oštećenje i citolizu enterocita, posledično dovodeći do pojave maldigestije i malresopcije. Dijareje teladi su praćene profuznim sadržajem iz creva, apatijom i dehidratacijom koje, komplikovane sekudarnom bakterijskom infekcijom, mogu dovesti i do letalnog ishoda. Nastanku dijareja doprinosi nagomilavanje osmotskih aktivnih materija zbog nemogućnosti razlaganja himusa u lumenu creva. Usled inflamatornih procesa u digestivnom traktu, dolazi do poremećaja u procesu varenja mleka i proizvodnje lab fermeta (himozina). Nesvareno mleko narušava osmotsku koncentraciju u crevima što prouzrokuje transudaciju tečnosti u lumen i povećanje zapremine tečnog sadržaja. On se ubrzano izbacuje što je klinički manifestovano pojavom dijareje. Cilj ovog rada je prikaže efekte peroralne upotrebe 20% rastvora lab fermenta (himozina) kao potpore u terapiji dijareja kod novorođene teladi. Lab ferment u sirištu teleta ima ulogu u procesu formiranja gruša i postepenoj proteolizi, a samim tim učestvuje u regulaciji osmotskog pritiska u crevima. Peroralnim davanjem 20% rastvora lab fermenta, teladima koja imaju očuvan apetit, potpomaže se proces varenja mleka i formiranja gruša. Zavisno od inteziteta dijareje, pored nadoknade tečnosti i antibiotske terapije, upotreba 20% rastvora lab-fermenta je bila veoma uspešna u bržem i efikasnijem uspostavljanju normalne konzistencije crevnog sadržaja. Takođe je zapaženo da samostalna upotreba lab fermenta kod dijareja nastalih usled presisavanja teladi, dovodi do skraćivanja njihovog trajanja., Neonatal diarrhea in calves is a very significant problem that causes large losses in cattle production. Infectious etiology of diarrhea, primarily Corona and Rota viruses, open the door to enteropathogenic bacteria, causing atrophy of intestinal villi, damage and cytolysis of enterocytes, consequently leading to mal - digestion and mal - absorption. Diarrhea in calves is accompanied by profuse contents from the intestines, apathy and dehydration, which, complicated by secondary bacterial infection, can lead to a fatal outcome. The accumulation of osmotic active substances contributes to the occurrence of diarrhea due to the impossibility of breaking down the chyme in the intestinal lumen. Due to inflammatory processes in the digestive tract, there is a disturbance in the process of milk digestion and the production of lab fermet (chymosin). Undigested milk disrupts the osmotic concentration in the intestine, which causes transudation of fluid into the lumen and an increase in the volume of the fluid content. It is excreted rapidly, which is clinically manifested by the appearance of diarrhea. The aim of this paper is to show the effects of oral use of a 20% solution of lab ferment (chymosin) as a support in the treatment of diarrhea in newborn calves. Lab ferment in calf rennet plays a role in the process of curd formation and gradual proteolysis, and thus participates in the regulation of osmotic pressure in the intestines. By orally giving a 20% solution of lab ferment to calves that have a preserved appetite, the process of milk digestion and curd formation is supported. Depending on the intensity of the diarrhea, in addition to fluid replacement and antibiotic therapy, the use of a 20% lab-ferment solution was very successful in establishing the normal consistency of the intestinal contents, faster and more efficiently. It has also been noted that the independent use of lab ferment in diarrhea, caused by sucking calves leads to a shortening of the disease.
- Published
- 2023