1. A Case of Quinacrine-induced Psychosis: Case Report
- Author
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Anangamanjari D Pedapudi, Ankita A Patel, and Jonathan T. Stewart
- Subjects
Pharmacology ,Drug ,Psychosis ,Induced psychosis ,Pediatrics ,medicine.medical_specialty ,business.industry ,media_common.quotation_subject ,Toxicology ,medicine.disease ,Psychiatric history ,medicine ,Pharmacology (medical) ,business ,Treatment resistant ,Adverse drug reaction ,media_common - Abstract
Background: Quinacrine is an older antimalarial drug that remains in use for a variety of illnesses including treatment-resistant giardiasis. Case Presentation: We report a patient with no prior psychiatric history who developed mild, prodromal psychiatric symptoms when treated with quinacrine for treatment-resistant giardiasis. Symptoms resolved when the drug was stopped, recurred with greater severity (requiring involuntary psychiatric hospitalization) when restarted and promptly resolved again when the drug was finally stopped. Conclusion: Although quinacrine remains in use today, providers may be unaware of its potential for serious neuropsychiatric toxicity.
- Published
- 2021
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